Results 101 to 110 of about 27,494 (299)
Foxc1 is required by pericytes during fetal brain angiogenesis
Biology Open, 2013 Summary Brain pericytes play a critical role in blood vessel stability and blood–brain barrier maturation. Despite this, how brain pericytes function in these different capacities is only beginning to be understood.
Julie A. Siegenthaler +9 more
doaj +1 more source
Pericyte-targeting drug delivery and tissue engineering
, 2016 Eunah Kang,1 Jong Wook Shin2 1School of Chemical Engineering and Material Science, 2Division of Allergic and Pulmonary Medicine, Department of Internal Medicine, College of Medicine, Chung-Ang University, Dongjak-Gu, Seoul, South Korea Abstract ...
Kang E, Shin JW
core
Regulation of pericyte contractility in health and disease [PDF]
, 2021 Pericytes regulate blood flow by constricting and dilating capillaries, especially in the brain, which requires a controlled supply of oxygen and energy substrates, and where the majority of the vascular resistance is in the capillaries.
Hirunpattarasilp, Chanawee
core
Advanced Science, EarlyView.MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei +3 more
wiley +1 more source
American Journal of Physiology-Cell PhysiologyPericytes are mural cells, embedded within the microvascular basement membrane and primarily involved in preservation of vessel integrity and regulation of vascular permeability and blood flow. Their study poses major challenges due to the absence of specific and reliable markers for their identification.
Izabela Tuleta +1 more
openaire +3 more sources
Complex mitochondrial morphology of a retinal deep capillary pericyte
, 2023 3D rendering of a pericyte mitochondria of a deep capillary exhibiting a convoluted shape. The mitochondrial loops and extensions follow the course of the pericyte processes wrapping the vessel ...
Deepayan Kar (16617657)
core +1 more source
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan +6 more
wiley +1 more source
Lung pericyte-like cells are functional interstitial immune sentinel cells
, 2017 Pericytes are perivascular PDGF receptor-β+ (PDGFRβ+) stromal cells required for vasculogenesis and maintenance of microvascular homeostasis in many organs.
Kristen L. Mittelsteadt +10 more
core +1 more source
Advanced Science, EarlyView.A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley +1 more source