Results 121 to 130 of about 27,494 (299)

Jagged1/Notch3 Signaling Modulates Hemangioma-Derived Pericyte Proliferation and Maturation

Cellular Physiology and Biochemistry, 2016
Background: The Notch signaling pathway has been implicated in the pericyte phenotype, but its exact roles in hemangioma-derived pericytes (Hem-pericytes) remain ill defined. Methods: Hem-pericytes were stimulated by immobilized recombinant Jagged1.
Yi Ji, Siyuan Chen, Bo Xiang, Yuan Li, Li Li, Qi Wang   +5 more
doaj   +1 more source

Equine Mesenchymal Stromal Cells retain a pericyte-like phenotype [PDF]

, 2017
Mesenchymal Stem/Stromal Cells (MSCs) have been used in human and equine regenerative medicine, and interest in exploiting their potential has increased dramatically over the years.
Lucy Dawson, Bruno Péault, Amilon, Karin, Tara A. Sheldrake, Nusrat Khan, Donadeu, Xavier, Peault, Bruno, Dawson, Lucy, Cristina L. Esteves, Karin Amilon, Menghini, Timothy, Rink, Elisabeth, Burgunde Elisabeth Rink, Timothy Menghini, Esteves, Cristina L, Sheldrake, Tara A, Khan, Nusrat, Francesc Xavier Donadeu   +17 more
core   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats

Scientific Reports, 2016
Subarachnoid hemorrhage (SAH) usually results from ruptured aneurysm, but how leaked hemoglobin regulates the microcirculation in the pathophysiology of early brain injury after SAH is still unclear.
Qiang Li, Yujie Chen, Bo Li, Chunxia Luo, Shilun Zuo, Xin Liu, John H. Zhang, Huaizhen Ruan, Hua Feng   +8 more
doaj   +1 more source

Comparative transcriptional profiling of key macrophage and fibroblast subpopulations in rheumatoid arthritis‐associated lung disease

Arthritis &Rheumatology, Accepted Article.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib, Ogechukwu Ezenwa, Joshua Sciurba, Eleanor B. Valenzi, John Sembrat, Brittany Cody, Jishnu Das, Robert Lafyatis, Dana P. Ascherman   +8 more
wiley   +1 more source

Role of Hippo/ACSL4 axis in ferroptosis-induced pericyte loss and vascular dysfunction in sepsis

Redox Biology
Sepsis is a critical condition characterized by a systemic inflammatory response to infection, often leading to severe vascular dysfunction and high mortality.
Yiyan Liu, Daiqin Bao, Han She, Zisen Zhang, Shifeng Shao, Zhengbin Wu, Yue Wu, Qinghui Li, Li Wang, Tao Li, Liangming Liu   +10 more
doaj   +1 more source

Pericytes in Muscular Dystrophies

, 2019
The muscular dystrophies are an heterogeneous group of inherited myopathies characterised by the progressive wasting of skeletal muscle tissue. Pericytes have been shown to make muscle in vitro and to contribute to skeletal muscle regeneration in several animal models, although recent data has shown this to be controversial.
Moyle, Louise Anne, Tedesco, Francesco Saverio, Benedetti, Sara   +2 more
openaire   +4 more sources

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Cd248a regulates pericyte development and viability in zebrafish

Communications Biology
CD248 is a pericyte marker during embryonic and tumor neovascularization. Although its expression pattern and function in mammalian pericytes have been extensively studied, its role in zebrafish pericytes remains largely unexplored.
Chao Wang, Yinming Zhong, Yi Zhang, Yiyang Jiang, Chenshiyu Wang, Lele An, Chunhua Luo, Lan Yang, Zhicheng He, Ying Yang, Min Luo, Min Mao, Wenying Wang, Qing Liu, Yu Shi, Yi-Fang Ping   +15 more
doaj   +1 more source