Results 171 to 180 of about 29,574 (291)

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

Role of SCF/c-KIT axis in pericyte TNT-guided vessel branching. [PDF]

Fluids Barriers CNS
Virgintino D, d'Amati A, Annese T, De Giorgis M, Bizzoca A, de Trizio I, Wälchli T, Sgarlata M, Ramchandran R, Perris R, Girolamo F, Errede M.   +11 more
europepmc   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

Degeneration of Interpericyte Tunneling Nanotubes Can Occur in the Absence of Pericyte Loss in Diabetic Retina Disease. [PDF]

Invest Ophthalmol Vis Sci
Qambari H, Hein M, Yu PK, Yu DY, Balaratnasingam C.   +4 more
europepmc   +1 more source

Noninvasive or minimally invasive neuromodulation in animal models of acute ischemic stroke: A systematic review and meta‐analysis

Neuroprotection, EarlyView.
This systematic review and meta‐analysis assessed the cytoprotective effects of neuromodulation in preclinical models of ischemic stroke. Pooled analyses showed that neuromodulation significantly reduced infarct volume and improved neurological outcomes.
Igor Caitano Salles, Mateus Paquesse Pellegrino, Jessica Borges Kroth, Clara Lucato dos Santos, Luca Schiliro Tristao, Jullyanna Sabrysna Morais Shinosaki, Wanderley Marques Bernardo, Adriana Bastos Conforto   +7 more
wiley   +1 more source

Loss of Pericytic Integrin-β1 Exacerbates Blood-Brain Barrier Damage and Hemorrhagic Brain Injury. [PDF]

Stroke
Culha-Taskin I, Nasrollahi A, Yao Y.
europepmc   +1 more source

A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia

The Journal of Pathology, EarlyView.
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang, Qizhi Zheng, Mindy K Graham, Ajay Vaghasia, Jianyong Liu, Jordan Gregg, Tracy Jones, Anuj Gupta, Nicole Castagna, Yan Zhang, Kornel Schuebel, Jennifer Meyers, Alyza Skaist, Dixie Hoyle, Jasmine Kung, Jessica Hicks, Alok Mishra, Yuhan Yang, William G Nelson, Angelo M De Marzo, Srinivasan Yegnasubramanian   +20 more
wiley   +1 more source

Pericyte dysfunction alone may be insufficient to drive tick-borne orthoflavivirus non-structural protein 1-mediated microvascular permeability. [PDF]

J Gen Virol
Brown E, Duruanyanwu J, Campagnolo P, Maringer K.   +3 more
europepmc   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen, Chenxi Jia, Zhuocheng Shi, Bianan Zhu, Yihang Yu, Xing Liu, Feng Liu, Jianwei Chen, Tao Xu, Yuanyuan Zhang, Deying Zhang, Guanghui Wei   +11 more
wiley   +1 more source

Algorithm-based quantification of tissue vascularization in immunohistochemical stainings of tissue sections. [PDF]

Sci Rep
Dastmaltschi A, Bozoglu T, Rajendran V, Shakouri SA, Bhardwaz S, Messerer D, Renner S, Bähr A, Wolf E, Weinberger T, Sager HB, Laugwitz KL, Kupatt C, Ziegler T.   +13 more
europepmc   +1 more source