Sleep, pericyte subtypes and cognitive decline in adults with and without Alzheimer's disease. [PDF]
Hamid M +10 more
europepmc +1 more source
Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell‐Based Therapies
Graphical presentation of stem cell‐based therapies for arterial dysfunction, endothelial repair and regeneration strategies. SMC, smooth muscle cell. ABSTRACT Arterial regeneration represents a critical frontier in cardiovascular medicine, as progressive endothelial dysfunction, maladaptive vascular smooth muscle cell (SMC) plasticity, and chronic ...
Yun‐Yu Ma, Shu‐Yao Zhu, Yi Song
wiley +1 more source
Conserved stromal EMT program controls regenerative capacity of mesenchymal stromal cells across multiple tissues. [PDF]
Kim JA +16 more
europepmc +1 more source
Single‐cell transcriptomic profiling reveals that endometrial polyps arise from estrogen‐driven disruption of stromal‐epithelial signaling. Stromal cells exhibit enhanced WNT, IGF, and VEGF pathways, promoting epithelial proliferation and vascular remodeling.
Tingwei Chen +12 more
wiley +1 more source
Role of transforming growth factorβ in neurovascular unit during cerebral small vessel disease. [PDF]
Li Y +7 more
europepmc +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Understanding the Molecular Basis of Pathological Retinal Angiogenesis: Roles of Lipids, Non-Coding RNAs, and Cellular Crosstalk. [PDF]
Sharma A, Kizy S, Singh NK.
europepmc +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Mechanisms, Imaging Phenotypes, and Therapeutic Advances of Neovascularization in Brain Metastases. [PDF]
Liu S +8 more
europepmc +1 more source
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow +6 more
wiley +1 more source

