Results 131 to 140 of about 106,411 (380)
Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source
Molecular mechanisms underlying therapeutic potential of pericytes
Background Pericytes are multipotent cells present in every vascularized tissue in the body. Despite the fact that they are well-known for more than a century, pericytes are still representing cells with intriguing properties.
C. Randall Harrell +5 more
doaj +1 more source
Plastic roles of pericytes in the blood–retinal barrier
The blood–retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully understood.
D. Park +13 more
semanticscholar +1 more source
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Microvascular pericytes in healthy and diseased kidneys
Szu-Yu Pan,1,2 Yu-Ting Chang,3 Shuei-Liong Lin1,31Renal Division, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; 2Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Yun-Lin, Taiwan;
Pan SY, Chang YT, Lin SL
doaj
Combined Effects of Pericytes in the Tumor Microenvironment
Pericytes are multipotent perivascular cells whose involvement in vasculature development is well established. Evidences in the literature also suggest that pericytes display immune properties and that these cells may serve as an in vivo reservoir of ...
Aline Lopes Ribeiro +1 more
doaj +1 more source
Pericytes in the tumor microenvironment.
Zhongyi Jiang +6 more
semanticscholar +1 more source
Targeting pericytes for therapeutic approaches to neurological disorders
Many central nervous system diseases currently lack effective treatment and are often associated with defects in microvascular function, including a failure to match the energy supplied by the blood to the energy used on neuronal computation, or a ...
Jinping Cheng +5 more
semanticscholar +1 more source
Pericytes in Vascular Development
Pericytes are essential components of capillaries in many tissues and organs, contributing to vessel stability and integrity, with additional contributions to microvascular function still being discovered. We review current and foundational studies identifying pericyte differentiation mechanics and their roles in the earliest stages of vessel formation.
Laura Beth Payne +4 more
openaire +3 more sources
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin +9 more
wiley +1 more source

