Results 141 to 150 of about 61,984 (301)
Isolation and Culture of Primary Pericytes from Mouse
Bio-ProtocolPericytes are essential for tissue homeostasis, functioning to regulate capillary blood flow. Dysfunctional pericytes are implicated in various pathologies, including cancer progression.
Tamara McErlain +2 more
doaj +1 more source
Role of pericytes in vascular morphogenesis
, 2005 Pericytes are solitary, smooth muscle-like mural cells that invest the wall of microvessels. For a long time, the functional significance of the presence and distribution of pericytes in the microvasculature was unclear.
Betsholtz, C. +5 more
core +1 more source
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Epilepsia, EarlyView.Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
Grafting purified cortical pericytes into mouse motor cortex [PDF]
, 2020 Brain regeneration through stem cell transplantation studies holds the potential to enhance functional recovery of the damaged brain. Most of the positive effects fostered by transplanted stem cells are believed to be fuelled by their multipotency to ...
Ganesh, Manju Gayathry
core
Epilepsia Open, EarlyView.Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini +9 more
wiley +1 more source
Simultaneous membrane potential recording from isolated pericytes; pericytes in contact.
, 2016 Schematic drawings and photomicrographs of dual recording from isolated pericytes in contact (A, B, designated P-P) on a coverslip or isolated without contact (C, D, designated PxP). The black bars = 10 microns.
Thomas L. Pallone (183981) +2 more
core +1 more source
Photodynamic Biomimetic Nanoparticles Accelerate Tumor Vascular Normalization Initiation
Exploration, EarlyView.Platelet‐mimetic IA@PM integrates apatinib‐driven vascular normalization with ICG‐mediated photodynamic therapy, creating a self‐amplifying vascular normalization therapy (VNT)–photodynamic therapy (PDT) cycle that accelerates the onset of the vascular normalization window and potentiates antitumor treatment.
Yufei Liu +6 more
wiley +1 more source
Pericyte-targeting drug delivery and tissue engineering
International Journal of Nanomedicine, 2016 Eunah Kang,1 Jong Wook Shin2 1School of Chemical Engineering and Material Science, 2Division of Allergic and Pulmonary Medicine, Department of Internal Medicine, College of Medicine, Chung-Ang University, Dongjak-Gu, Seoul, South Korea Abstract ...
Kang E, Shin JW
doaj
Head &Neck, EarlyView.ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik +6 more
wiley +1 more source
Microvascular pericytes contain muscle and nonmuscle actins
, 2018 We have affinity-fractionated rabbit antiactin immunoglobulins (IgG) into classes that bind preferentially to either muscle or nonmuscle actins. The pools of muscle- and nonmuscle-specific actin antibodies were used in conjunction with fluorescence ...
Herman, Ira M., D'Amore, Patricia
core +1 more source