Results 131 to 140 of about 61,984 (301)
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Pericytes modulate endothelial inflammatory response during bacterial infection
mBioPericytes are located around blood vessels, in close contact with endothelial cells. We discovered that pericytes dampen pro-inflammatory endothelial cell responses. Endothelial cells co-cultured with pericytes had markedly reduced expression of adhesion
Thaynara P. Carvalho +12 more
doaj +1 more source
Research advances of pericytes in renal interstitial fibrosis
Linchuang shenzangbing zazhi, 2022 Pericytes are mesenchymal cells in contact with endothelial cells and partially embedded in the basement membrane of blood vessels.Pericytes possess the capability of differentiating and their surface markers change according to different tissues，various
Feng Yi-duo, Diao Zong-li, Liu Wen-hu
doaj
Neonatal pancreatic pericytes support β-cell proliferation
, 2017 Objective: The maintenance and expansion of β-cell mass rely on their proliferation, which reaches its peak in the neonatal stage. β-cell proliferation was found to rely on cells of the islet microenvironment.
Shani Mizrachi +5 more
core +1 more source
BMEMat, EarlyView.An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu +5 more
wiley +1 more source
Brain Pericytes — Crucial Regulators of Neuroinflammation in Ischemic Stroke
Neuropharmacology and TherapyInflammation is a key element in the pathophysiology of ischemic stroke. The current effective treatments for ischemic stroke are almost exclusively based on reperfusion of occluded vessels.
Ziyi Chen +5 more
doaj +1 more source
Microvascular bioengineering: a focus on pericytes
, 2019 Capillaries within the microcirculation are essential for oxygen delivery and nutrient/waste exchange, among other critical functions. Microvascular bioengineering approaches have sought to recapitulate many key features of these capillary networks, with
Huaning Zhao +3 more
core +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
BMEMat, EarlyView.This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu +9 more
wiley +1 more source
Translational NeurodegenerationBackground Effective therapies for Alzheimer’s disease (AD) remain to be developed. APOE4 is the strongest genetic risk factor for late-onset AD. Pericyte degeneration and blood–brain barrier (BBB) disruption are thought to be early biomarkers of AD and ...
Chuanfeng Xiong +19 more
doaj +1 more source