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Biology of the renal pericyte

Nephrology Dialysis Transplantation, 2012
Pericytes are cells of mesenchymal origin that are intimately involved in the development and stabilization of vascular networks. Novel studies of their role in inflammation have identified that pericytes are not only major contributors to the activated matrix depositing myofibroblast populations seen in progressive renal fibrosis but perhaps even more
Stuart W, Smith   +2 more
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Pericytes in kidney fibrosis

Current Opinion in Nephrology & Hypertension, 2013
Pericytes and perivascular fibroblasts have emerged as poorly appreciated yet extensive populations of mesenchymal cells in the kidney that play important roles in homeostasis and responses to injury. This review will update readers on the evolving understanding of the biology of these cells.Fate mapping has identified pericytes and perivascular ...
Shuyu, Ren, Jeremy S, Duffield
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Cochlear Capillary Pericytes

2019
Capillary pericytes in the cochlea of mammals are-compared to pericytes in other tissues, like the CNS-relatively poorly researched. To begin with, there is still a considerable debate as to whether the very last precapillary arterioles should-due to their contractile properties-may be considered to be pericytes.However, cochlear capillary pericytes ...
Martin, Canis, Mattis, Bertlich
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Pericytes in the Umbilical Cord

2019
The structural components of the umbilical cord, including two arteries and one vein, the stromal region/Wharton's jelly, and amniotic epithelial membrane, are well described at various time points of gestation. Over the last two decades, evidence has emerged that multipotent cells sharing properties of mesenchymal stromal cell and pericytes/mural ...
Andrée, Gauthier-Fisher   +2 more
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Pericytes in Skeletal Muscle

2019
Skeletal muscle regeneration is a highly orchestrated process and involves the activation of many cellular and molecular pathways. Although satellite cells (SCs) are the major cell type responsible for muscle regeneration, pericytes show remarkable myogenic potential and various advantages as cell therapy in muscular disorders.
Jyoti, Gautam, Yao, Yao
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Pericyte Biology in Zebrafish

2018
The zebrafish is an outstanding model for studying vascular biology in vivo. Pericytes and vascular smooth muscle cells can be imaged as they associate with vessels and provide stability and integrity to the vasculature. In zebrafish, pericytes associate with the cerebral and trunk vasculature on the second day of development, as assayed by pdgfrβ and ...
Nabila, Bahrami, Sarah J, Childs
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Pericytes and vascular stability

Experimental Cell Research, 2006
Newly formed endothelial tubes are initially unstable and subsequently become stabilized through the formation of a perivascular matrix and the association with pericytes. The presence of pericyte per se is not sufficient for vascular stability. Instead, specific qualities of the cells are required that seem to correlate with marker expression and the ...
Desiree, von Tell   +2 more
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Pericytes in Bone Marrow

2019
Bone marrow environments are composed of multiple cell types, most of which are thought to be derived from mesenchymal stem cells. In mouse bone marrow, stromal cells with CD45- Tie2- CD90- CD51+ CD105+ phenotype, Nestin-GFP+, CXCL12-abundant reticular (CAR) cells, PDGFRα+ Sca-1+ or CD51+ PDGFRα+, and Prx-1-derived CD45- Ter119- PDGFRα+ Sca-1 ...
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Pericytes in Tissue Engineering

2018
Pericytes have crucial roles in blood-brain barrier function, blood vessel function/stability, angiogenesis, endothelial cell proliferation/differentiation, wound healing, and hematopoietic stem cells maintenance. They can be isolated from fetal and adult tissues and have multipotential differentiation capacity as mesenchymal stem cells (MSCs).
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The Active Role of Pericytes During Neuroinflammation in the Adult Brain

Cellular and Molecular Neurobiology, 2022
Maria Deli   +2 more
exaly  

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