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Pericytes in the microvasculature [PDF]

open access: yesCardiovascular Research, 1996
Pericytes, also known as Rouget cells or mural cells, are associated abluminally with all vascular capillaries and post-capillary venules. Differences in pericyte morphology and distribution among vascular beds suggest tissue-specific functions. Based on their location and their complement of muscle cytoskeletal proteins, pericytes have been proposed ...
Karen Hirschi, Patricia D'Amore
exaly   +3 more sources

Pericyte physiology

The FASEB Journal, 1993
Endothelial cells are the primary physical barrier between blood and tissue in microvessels. The other capillary and post‐capillary venule wall cell is the pericyte. The literature on the biology of endothelium is appreciable but less is known about pericytes.
D, Shepro, N M, Morel
openaire   +2 more sources

Pericytes in Atherosclerosis

2019
Pericytes are pluripotent cells found in the vascular wall of both capillaries and large blood vessels. Pericytes are highly heterogeneous cells in terms of phenotype, tissue distribution, origin and functions, and they play an important role in the regulation of vascular morphogenesis and function.
Volha, Summerhill, Alexander, Orekhov
openaire   +2 more sources

Pericytes in the Gut

2019
This review chapter describes the current knowledge about the nature of pericytes in the gut, their interaction with endothelial cells in blood vessels, and their pathophysiological functions in the setting of chronic liver disease. In particular, it focuses on the role of these vascular cell types and related molecular signaling pathways in ...
Marta, Ramirez   +3 more
openaire   +2 more sources

Pericytes in the Retina

2019
Pericytes (PCs) are specialized cells located abluminal of endothelial cells (ECs) on capillaries, embedded within the same basement membrane. They are essential regulators of vascular development, remodeling, and blood-retina-barrier (BRB) tightness and are therefore important components to maintain tissue homeostasis.
Andrea, Trost   +3 more
openaire   +2 more sources

Pericyte Secretome

2018
The role of pericytes seems to extend beyond their known function in angiogenesis, fibrosis and wound healing, blood-brain barrier maintenance, and blood flow regulation. More and more data are currently accumulating indicating that pericytes, uniquely positioned at the interface between blood and parenchyma, secrete a large plethora of different ...
Abderahim, Gaceb, Gesine, Paul
openaire   +2 more sources

Pericytes in the Heart

2019
Mural cells known as pericytes envelop the endothelial layer of microvessels throughout the body and have been described to have tissue-specific functions. Cardiac pericytes are abundantly found in the heart, but they are relatively understudied.
Linda L, Lee, Vishnu, Chintalgattu
openaire   +2 more sources

Pericytes in the Lung

2019
The lung has numerous roles, including gas exchange, immune surveillance, and barrier function. Being a highly vascularized organ, the lung receives dual blood supply from both the pulmonary and bronchial circulation. Therefore, pericytes likely play a prominent role in lung physiology given their localization in the perivascular niche.
Chi F, Hung   +2 more
openaire   +2 more sources

Focus on cardiac pericytes

Pflügers Archiv - European Journal of Physiology, 2013
The wall of myocardial terminal vessels, consisting of a continuous endothelial tube with an adventitial coat of pericytes in their extracellular matrix, constitutes a remarkably tight barrier to solute transport between the blood and the parenchyma. This constructional principle of precapillary arterioles, capillaries and postcapillary venules extends
Stephan, Nees   +2 more
openaire   +2 more sources

Pericyte differentiation.

Clinical orthopaedics and related research, 1995
Pericytes are defined in vivo by their location: They are embedded within the basement membrane of microvessels. They form an integral part of the microvascular wall and are believed to participate in angiogenesis, although their precise role is not clear. Pericytes derived from the retinal microvasculature have been cultured and identified by a series
Schor, A M   +4 more
openaire   +2 more sources

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