Results 31 to 40 of about 106,411 (380)
Brain Microvascular Pericytes—More than Bystanders in Breast Cancer Brain Metastasis
Cells, 2022 Brain tissue contains the highest number of perivascular pericytes compared to other organs. Pericytes are known to regulate brain perfusion and to play an important role within the neurovascular unit (NVU).
Danyyl Ippolitov +3 more
doaj +1 more source
An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ [PDF]
, 2012 Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are ...
Agmon Y +51 more
core +2 more sources
Bone Research, 2022 Vascular regeneration is a challenging topic in tissue repair. As one of the important components of the neurovascular unit (NVU), pericytes play an essential role in the maintenance of the vascular network of the spinal cord.
Sipin Zhu +10 more
semanticscholar +1 more source
Pericytes: The lung-forgotten cell type
Frontiers in Physiology, 2023 Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal surface of microvessels, where they provide structural and biochemical support. Pericytes have been implicated in numerous lung diseases including pulmonary arterial hypertension (PAH) and allergic asthma due to their ability to differentiate into scar-forming ...
Annelise T. Garrison +5 more
openaire +3 more sources
Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease [PDF]
, 2010 Because regional blood flow increases in association with the increased metabolic demand generated by localised increases in neural activity, functional imaging researchers often assume that changes in blood flow are an accurate read-out of changes in ...
Attwell, D., Hall, C.N., Hamilton, N.B.
core +3 more sources
Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes
Science, 2019 Pericytes put the squeeze on cognition Like a computer, the brain needs a reliable source of power, which is provided as oxygen and glucose in the blood. However, in many neurological disorders this energy supply is disrupted.
R. Nortley +17 more
semanticscholar +1 more source
Role of pericytes in blood–brain barrier preservation during ischemia through tunneling nanotubes
Cell Death and Disease, 2022 Crosstalk mechanisms between pericytes, endothelial cells, and astrocytes preserve integrity and function of the blood-brain-barrier (BBB) under physiological conditions. Long intercellular channels allowing the transfer of small molecules and organelles
F. Pisani +5 more
semanticscholar +1 more source
Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]
, 2015 Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco +10 more
core +1 more source
Nature Communications, 2021 Defective pericyte-endothelial cell interaction in tumors leads to a chaotic, poorly organized and dysfunctional vasculature. However, the underlying mechanism behind this is poorly studied.
Ya-Ming Meng +12 more
semanticscholar +1 more source
Pericytes in Cerebrovascular Diseases: An Emerging Therapeutic Target
Frontiers in Cellular Neuroscience, 2019 Pericytes are functional components of the neurovascular unit (NVU) that are located around the blood vessels, and their roles in the regulation of cerebral health and diseases has been reported.
Xiaojuan Su +8 more
doaj +1 more source