Results 31 to 40 of about 86,775 (289)

Pericyte mechanics and mechanobiology [PDF]

Journal of Cell Science, 2021
ABSTRACT Pericytes are mural cells of the microvasculature, recognized by their thin processes and protruding cell body. Pericytes wrap around endothelial cells and play a central role in regulating various endothelial functions, including angiogenesis and inflammation.
Claire A. Dessalles, Avin Babataheri, Abdul I. Barakat   +2 more
openaire   +3 more sources

Pericytes and Neurovascular Function in the Healthy and Diseased Brain

Frontiers in Cellular Neuroscience, 2019
Pericytes are multi-functional cells embedded within the walls of capillaries throughout the body, including the brain. Pericytes were first identified in the 1870s, but little attention was paid to them during the following century.
Lachlan S. Brown, Catherine G. Foster, Jo-Maree Courtney, Natalie E. King, David W. Howells, Brad A. Sutherland   +5 more
doaj   +1 more source

Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke

Frontiers in Cellular Neuroscience, 2023
Pericytes play an indispensable role in various organs and biological processes, such as promoting angiogenesis, regulating microvascular blood flow, and participating in immune responses.
Jiaqi Fu, Jiaqi Fu, Huazheng Liang, Ping Yuan, Zhenyu Wei, Ping Zhong, Ping Zhong   +6 more
doaj   +1 more source

Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]

, 2014
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia, Kelley, Stephen P., Peppiatt-Wildman, Claire M., Wildman, Scott S.P.   +3 more
core   +1 more source

Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]

, 2018
The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco, Biró, Zsolt, Fehér, János, Micera, Alessandra, Orlando, Maria Patrizia, Scuderi, Gianluca, Spoletini, Maria Luisa, Taurone, Samanta, Turchetta, Rosaria, Varsányi, Balázs   +9 more
core   +1 more source

Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]

, 2019
Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S., Han, Fei, Morris, John C., Perlmutter, Joel S., Perrin, Richard J., Wang, Qing, Wang, Yong, Xu, Jinbin   +7 more
core   +2 more sources

The complex TIE between macrophages and angiogenesis [PDF]

, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M., Avraham‐Davidi I., Baer C., Bailey A. S., Barnett F. H., Bonnardel J., Chakarov S., Chen L., Coffelt S. B., Corliss B. A., Cursiefen C., Daly C., Davies L. C., Davies L. C., De Palma M., De Palma M., De Palma M., De Palma M., De Palma M., De Spiegelaere W., DeFalco T., Deshmane S. L., Detry B., Dimova I., Dimova I., Eklund L., Elamaa H., Eubank T. D., Fantin A., Ferrari G., Fukuhara S., Ganta V. C., Ganta V. C., García S., Gerri C., Grunewald M., Guo L., Gurevich D. B., Hamm A., Hazan A. D., He H., Hoeffel G., Itoh M., Jetten N., Kim M., Kochhan E., Korhonen E. A., Korpelainen E. I., Krishnasamy K., Kumar A. H., Leibovich S. J., Lim H. Y., Liu C., Lucas T., Master Z., Metharom P., Michaeli S., Moldovan N. I., Moore E. M., Mueller S. B., Murdoch C., Murray P. J., Patel A. S., Polverini P. J., Potente M., Pucci F., Saharinen P., Saharinen P., Schif‐Zuck S., Schmeisser A., Seaman S. A., Seok S. H., Spiller K. L., Venneri M. A., Vestweber D., Webster N. L., West M. E. D., Willenborg S., Yamamoto S., Zajac E., Zenker D., Zhang W.   +81 more
core   +2 more sources

PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]

, 2019
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit, Bocchicchio, Sebastian, Irusta, Griselda, May, Maria, Parborell, Maria Fernanda Agustina, Pazos Maidana, María Camila, Sequeira, Gonzalo Ricardo, Tesone, Marta   +7 more
core   +1 more source

Calcium Signalling in Pericytes [PDF]

Journal of Vascular Research, 2014
Recent advances in pericyte research have contributed to our understanding of the physiology and pathophysiology of microvessels. The microvasculature consists of arteriolar and venular networks located upstream and downstream of the capillaries.
Theodor, Burdyga, Lyudmyla, Borysova
openaire   +2 more sources

Immune regulation by pericytes: modulating innate and adaptive immunity

Frontiers in Immunology, 2016
Pericytes are mural cells that surround endothelial cells in small blood vessels. Pericytes have traditionally been credited with structural functions, being essential for vessel maturation and stabilization.
Rocio Navarro, Marta Compte, Luis Alvarez-Vallina, Laura Sanz   +3 more
doaj   +1 more source