Results 81 to 90 of about 106,411 (380)

The physiological functions of central nervous system pericytes and a potential role in pain [version 1; referees: 2 approved]

F1000Research, 2018
Central nervous system (CNS) pericytes regulate critical functions of the neurovascular unit in health and disease. CNS pericytes are an attractive pharmacological target for their position within the neurovasculature and for their role in ...
Nicholas Beazley-Long, Alexandra M Durrant, Matthew N Swift, Lucy F Donaldson   +3 more
doaj   +1 more source

Efficient Treatment of Pulpitis via Transplantation of Human Pluripotent Stem Cell-Derived Pericytes Partially through LTBP1-Mediated T Cell Suppression

Biomedicines, 2023
Dental pulp pericytes are reported to have the capacity to generate odontoblasts and express multiple cytokines and chemokines that regulate the local immune microenvironment, thus participating in the repair of dental pulp injury in vivo.
Anqi Li, Zhuoran Li, Weicheng Chiu, Chuanfeng Xiong, Qian Chen, Junhua Chen, Xingqiang Lai, Weiqiang Li, Qiong Ke, Jia Liu, Xinchun Zhang   +10 more
doaj   +1 more source

Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]

, 2016
open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio, Bernardini, Nunzia, Blandizzi, Corrado, Buccianti, Piero, Campani, Daniela, Castagna, Maura, Colucci, Rocchina, Di Candio, Giulio, Dolfi, Amelio, ERREDE, Mariella, GIROLAMO, FRANCESCO, Ippolito, Chiara, Segnani, Cristina, Tirotta, Erika, Villanacci, Vincenzo, VIRGINTINO, Daniela   +15 more
core   +2 more sources

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Pericyte-mediated regulation of angiogenesis during cutaneous wound healing in adult zebrafish

Communications Biology
Pericytes are mural cells that wrap small caliber vessels, playing a crucial role in stabilizing vascular structure. Upon induction of angiogenesis, pericytes were thought to detach from the vessel wall, thereby facilitating the sprouting of endothelial ...
Tomohiro Ishii, Shinya Yuge, Koji Ando, Weibin Zhou, Shigetomo Fukuhara   +4 more
doaj   +1 more source

Apelin Protects Primary Rat Retinal Pericytes from Chemical Hypoxia-Induced Apoptosis

Journal of Ophthalmology, 2015
Pericytes are a population of cells that participate in normal vessel architecture and regulate permeability. Apelin, as the endogenous ligand of G protein-coupled receptor APJ, participates in a number of physiological and pathological processes.
Li Chen, Yong Tao, Jing Feng, Yan Rong Jiang   +3 more
doaj   +1 more source

Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury [PDF]

, 2017
Ischemia-reperfusion injury (IRI) is a leading cause of AKI. This common clinical complication lacks effective therapies and can lead to the development of CKD.
Alimperti, Stella, Calvino, Jenna E., Campos-Bilderback, Silvia B., Chen, Christopher S., Crackower, Michael A., Dolinski, Brian M., Dovey, Jennifer, Duffield, Jeremy S., Gomez, Ivan G., Huang, Angela, Marsh, Graham, McCurley, Amy, Molitoris, Bruce A., Moore, Shaun, Mugford, Joshua W., Polacheck, William J., Qian, Fang, Quigley, Catherine, Reynolds, Taylor L., Sandoval, Ruben M., Violette, Shelia M., Weinreb, Paul H.   +21 more
core   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Inhibition of Lysyl Oxidases Impairs Migration and Angiogenic Properties of Tumor-Associated Pericytes

Stem Cells International, 2017
Pericytes are important cellular components of the tumor microenviroment with established roles in angiogenesis and metastasis. These two cancer hallmarks are modulated by enzymes of the LOX family, but thus far, information about LOX relevance in tumor ...
Aline Lopes Ribeiro, Carolini Kaid, Patrícia B. G. Silva, Beatriz A. Cortez, Oswaldo Keith Okamoto   +4 more
doaj   +1 more source

Gene therapy targeting inflammatory pericytes corrects angiopathy during diabetic wound healing

Frontiers in Immunology, 2022
Wound healing is impaired in the diabetic status, largely attributable to diabetes-associated angiopathy. Pericytes play critical roles in the stabilization of the formed vessels.
Wenxv Jin, Xiong Chen, Lingguo Kong, Chongqing Huang   +3 more
doaj   +1 more source