Postoperative cognitive dysfunction (POCD) is a common postoperative neurological complication, with memory consolidation deficits being one of its prominent features.
Zun-sai Feng +7 more
doaj +1 more source
Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity. [PDF]
Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain neurons in the CNS during development and control plasticity in the adult CNS.
Berretta, Sabina +6 more
core +5 more sources
Editorial: Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders [PDF]
Dysregulated synaptic plasticity and excitatory inhibitory (E/I) imbalance are molecular hallmarks of multiple neuropsychiatric disorders. Perineuronal nets (PNNs) are condensed portions of the extracellular matrix (ECM) that stabilize homeostatic ...
Browne, Caroline A. +3 more
core +2 more sources
Age Impacts Perineuronal Net Density in the Somatosensory Genital Cortex Independently of Gonadal Steroid Hormones [PDF]
A hallmark of pubertal development is the rise in gonadal hormone secretions and the subsequent onset of sexual behavior. The size of the somatosensory genital cortex increases in response to both this rise in gonadal steroid hormones and sexual ...
Warren, Ian D
core +1 more source
Manipulating the Perineuronal Net in the Deep Cerebellar Nucleus [PDF]
Perineuronal nets (PNN) are a type of specialized extracellular matrix in the central nervous system. The PNN forms during postnatal development but the ontogeny of the PNN has yet to be elucidated.
O\u27Dell, Deidre E.
core +1 more source
Diverse developmental trajectories of perineuronal nets during vertebrate nervous system construction [PDF]
2018 Spring.Includes bibliographical references.In the central nervous system, aggregated extracellular matrix compounds known as perineuronal nets (PNNs) shape patterns of neural connectivity over development. Removing PNNs restores juvenile-like states
Edwards, Jacob
core
Microglial depletion increases aggrecan and hyaluronan levels in the diffuse and aggregated extracellular matrix of the mouse brain [PDF]
The extracellular matrix (ECM) in the brain can be divided into aggregated ECM, such as perineuronal nets (PNNs) around neurons, and diffuse ECM, which is present throughout the brain parenchyma.
Arikawa-Hirasawa, Eri +5 more
core +2 more sources
NPY-Y1 receptor signaling controls spatial learning and perineuronal net expression [PDF]
Bertocchi, I. +5 more
core +1 more source
Parvalbumin and autism: different causes, same effect? [PDF]
Filice, Federica, Schwaller, Beat
core +1 more source
Altered lipid peroxidation, perineuronal net and oligodendrocyte markers in the frontal cortex of a dual-hit neurodevelopmental model support its relevance to schizophrenia. [PDF]
Esuaikoh V +8 more
europepmc +1 more source

