Results 91 to 100 of about 17,102,650 (298)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Theoretical and methodological foundations of pedagogical interaction of the educational process participants [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010 Theoretical and methodological foundations of pedagogical interaction of the educational process participants at the system of higher school in the XX century are investigated.
Gonchar O.V.
doaj
Revista Brasileira de Zootecnia, 2007 O experimento foi realizado no período de dezembro de 2002 a abril de 2003, com o objetivo de avaliar, em capim-mombaça, o efeito de duas fontes de fósforo (superfosfato simples + superfosfato triplo e termofosfato magnesiano YoorinÒ), em função dos dias
Ulysses Cecato +6 more
doaj +1 more source
The period functions' higher order derivatives [PDF]
, 2012 We prove a formula for the $n$-th derivative of the period function $T$ in a period annulus of a planar differential system. For $n = 1$, we obtain Freire, Gasull and Guillamon formula for the period's first derivative \cite{FGG}.
Sabatini, Marco
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Period polynomials and Ihara brackets
, 2006 Schneps [J. Lie Theory 16 (2006), 19--37] has found surprising links between Ihara brackets and even period polynomials. These results can be recovered and generalized by considering some identities relating Ihara brackets and classical Lie brackets. The
Luque, Jean-Gabriel +2 more
core +1 more source
Connecting period-doubling cascades to chaos [PDF]
, 2010 The appearance of infinitely-many period-doubling cascades is one of the most prominent features observed in the study of maps depending on a parameter. They are associated with chaotic behavior, since bifurcation diagrams of a map with a parameter often
Sander, Evelyn, Yorke, James A.
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source