Results 41 to 50 of about 85,043 (305)

Regulation of αENaC expression by the circadian clock protein Period 1 in mpkCCDc14 cells [PDF]

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2010
The epithelial sodium channel (ENaC) mediates the fine-tuned regulation of external sodium (Na) balance. The circadian clock protein Period 1 (Per1) is an aldosterone-induced gene that regulates mRNA expression of the rate-limiting alpha subunit of ENaC (αENaC).
VA Medical Center, Gainesville, FL, USA ( host institution ), Gumz, Michelle L. ( author ), Cheng, Kit-Yan ( author ), Lynch, I. Jeanette ( author ), Stow, Lisa R. ( author ), Greenlee, Megan M. ( author ), Cain, Brian D. ( author ), Wingo, Charles S. ( author )   +7 more
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The discoveries of molecular mechanisms for the circadian rhythm: The 2017 Nobel Prize in Physiology or Medicine

Biomedical Journal, 2018
Circadian clocks evolved to allow plants and animals to adapt their behaviors to the 24-hr change in the external environment due to the Earth's rotation.
Rong-Chi Huang
doaj   +1 more source

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders

Frontiers in Molecular Neuroscience, 2023
IntroductionCircadian rhythm maintains the sleep–wake cycle in biological systems. Various biological activities are regulated and modulated by the circadian rhythm, disruption of which can result in onset of diseases.
Md. Zubbair Malik, Mohammed Dashti, Yasmin Fatima, Arshad Channanath, Sumi Elsa John, R. K. Brojen Singh, Fahd Al-Mulla, Thangavel Alphonse Thanaraj   +7 more
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Diel pattern of circadian clock and storage protein gene expression in leaves and during seed filling in cowpea (Vigna unguiculata) [PDF]

, 2018
Background Cowpea (Vigna unguiculata) is an important source of protein supply for animal and human nutrition. The major storage globulins VICILIN and LEGUMIN (LEG) are synthesized from several genes including LEGA, LEGB, LEGJ and CVC (CONVICILIN).
Egea Gutiérrez-Cortines, Marcos, Fernández, Juan A., Letourneux, Lisa, Martos Fuentes, Marina Marta, Ruiz Hernández, María Víctoria, Terry López, Marta Isabel, Weiss, Julia Rosl   +6 more
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A global search for novel transcription factors impacting the Neurospora crassa circadian clock

G3: Genes, Genomes, Genetics, 2021
In order to identify new players modulating the circadian clock in the model Neurospora crassa, we adopted a reverse genetics strategy. Thus, we focused on transcription factors knockouts and crossed them to strains containing circadian luciferase ...
Felipe Muñoz-Guzmán, Valeria Caballero, Luis F Larrondo   +2 more
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Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7. [PDF]

, 2017
c-Jun N-terminal kinase (JNK) is a member of the mitogen-activated protein kinase family and controls various physiological processes including apoptosis. A specific upstream activator of JNKs is the mitogen-activated protein kinase kinase 7 (MKK7).
Deki-Arima, Norie, Fujimori-Tonou, Noriko, Hirayama, Jun, Iwatsuki, Mamiko, Kaneko, Asahito, Kawasaki, Hiroshi, Marth, Jamey D, Matsuoka, Masato, Miyamura, Norio, Nishina, Hiroshi, Okamoto-Uchida, Yoshimi, Penninger, Josef M, Shibata, Shigenobu, Yamanaka, Koji, Yamanashi, Yuji, Yamasaki, Tokiwa   +15 more
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Plant responses to photoperiod [PDF]

, 2009
Photoperiod controls many developmental responses in animals, plants and even fungi. The response to photoperiod has evolved because daylength is a reliable indicator of the time of year, enabling developmental events to be scheduled to coincide with ...
Abe, Achard, Adams, Adams, Alabadi, An, Asai, Aukerman, Balasubramanian, Banerjee, Batutis, Beales, Ben-Naim, Berardini, Bernier, Blazquez, Blázquez, Blázquez, Bollman, Bongard-Pierce, Borchert, Bouveret, Bäurle, Böhlenius, Cerdán, Chae, Chailkhyan, Chen, Chen, Chien, Chincinska, Clarke, Cockcroft, Corbesier, David, Devlin, Doi, Dudley, Duncan, Fahlgren, Farré, Foster, Fowler, Gandikota, Gardner, Giavalisco, Goldman, Gonthier, Grigg, Hackett, Halliday, Hayama, Hayama, Haywood, He, He, Henderson, Heyer, Holm, Hotta, Hsu, Hunter, Hunter, Imaizumi, Imaizumi, Izawa, Jackson, Jackson, Jackson, Jackson, Jaeger, Jang, Jung, Kanrar, Kelly, Kim, Kim, Kim, Kim, Kojima, Komiya, Kotake, Kusnetsov, Laubinger, Lauter, Lee, Lee, Lin, Martinez-Garcia, Martínez, Mathieu, McClung, Michael, Moon, Mouradov, Más, Nilsson, Onouchi, Orkwiszewski, Osterlund, Park, Peragine, Pineiro, Poethig, Poethig, Pouteau, Razem, Reeves, Roberts, Robinson, Robson, Roden, Rodriguez-Falcon, Saijo, Samach, Sawa, Schmid, Schwarz, Searle, Seo, Singer, Sivitz, Smith, Somers, Souer, Stadler, Steward, Suàrez-López, Swiezewski, Takada, Takeno, Tamaki, Telfer, Tessadori, Thomas, Turner, Valverde, Vega, Von Arnim, Wang, Wang, Weigel, Wenkel, Wigge, Willmann, Wu, Xie, Yamaguchi, Yan, Yanovsky, Yanovsky, Yoo, Yoo, Yu, Zeevaart   +154 more
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FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora

Nature Communications, 2019
Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the ...
Xiao Liu, Ahai Chen, Angélica Caicedo-Casso, Guofei Cui, Mingjian Du, Qun He, Sookkyung Lim, Hang J. Kim, Christian I. Hong, Yi Liu   +9 more
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The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis [PDF]

, 2017
Most living organisms developed systems to efficiently time environmental changes. The plant-clock acts in coordination with external signals to generate output responses determining seasonal growth and flowering time.
De Clercq, Rebecca, De Jaeger, Geert, De Milde, Liesbeth, Dhondt, Stijn, Eeckhout, Dominique, Fernandez Calvo, Patricia, Gevaert, Kris, Goossens, Alain, Heyndrickx, Ken, Inzé, Dirk, Iñigo, Sabrina, Pauwels, Laurens, Ritter Traub, Andrés, Ron, Mily, Shi, Hua, Somers, David E, Vanden Bossche, Robin, Vandepoele, Klaas   +17 more
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Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Mitochondria are major cellular energy suppliers and have to cope with changes in nutrient supply and energy demand that naturally occur throughout the day. We obtained the first, to our knowledge, comprehensive mitochondrial proteome around the clock and identified extensive oscillations in mitochondrial protein abundance that ...
Neufeld-Cohen, A., Robles, M., Aviram, R., Manella, G., Adamovich, Y., Ladeuix, B., Nir, D., Rousso-Noori, L., Kuperman, Y., Golik, M., Mann, M., Asher, G.   +11 more
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