Results 51 to 60 of about 43,915 (298)
PLoS ONE, 2016 Mammalian Cryptochromes, CRY1 and CRY2, function as principal regulators of a transcription-translation-based negative feedback loop underlying the mammalian circadian clockwork.
Arisa Hirano +6 more
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Period Protein Is Necessary for Circadian Control of Egg Hatching Behavior in the Silkmoth Antheraea pernyi [PDF]
Neuron, 1996 We examined the molecular basis of the circadian control of egg hatching behavior in the silkmoth Antheraea pernyi. Egg hatching is rhythmically gated, persists under constant darkness, and can be entrained by light by midembryogenesis. The time of appearance of photic entrainment by the silkmoth embryo coincides with the appearance of Period (PER) and
Sauman, Ivo +3 more
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Generation of Human CRY1 and CRY2 Knockout Cells Using Duplex CRISPR/Cas9 Technology
Frontiers in Physiology, 2019 Circadian clocks are endogenous oscillators essential for orchestrating daily rhythms in physiology, metabolism and behavior. While mouse models have been instrumental to elucidate the molecular mechanism of circadian rhythm generation, our knowledge ...
Teresa Börding +10 more
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Rheostatic Balance of Circadian Rhythm and Autophagy in Metabolism and Disease
Frontiers in Cell and Developmental Biology, 2020 Circadian rhythms are physical, behavioral and environmental cycles that respond primarily to light and dark, with a period of time of approximately 24 h.
Xiang Wang +8 more
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Neuron, 1995 The Drosophila period protein (PER) is a predominantly nuclear protein and a likely component of a circadian clock. PER is required for daily oscillations in the transcription of its own gene and thus participates in a circadian feedback loop.
Curtin, Kathryn D +2 more
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Circadian Clock Neurons in the Silkmoth Antheraea pernyi: Novel Mechanisms of Period Protein Regulation [PDF]
Neuron, 1996 We examined Period (PER) protein regulation in the brain of the silkmoth Antheraea pernyi. PER expression is restricted to the cytoplasm and axons of eight neurons, with no evidence of temporal movement into the nucleus. These neurons appear to be circadian clock cells, because PER and per mRNA are colocalized and their levels oscillate in these cells,
Sauman, Ivo, Reppert, Steven M
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Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance.
PLoS Genetics, 2019 Circadian clocks control daily rhythms in behavior and physiology. In Drosophila, the small ventral lateral neurons (sLNvs) expressing PIGMENT DISPERSING FACTOR (PDF) are the master pacemaker neurons generating locomotor rhythms.
Zhenxing Liu +8 more
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Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock
eLife, 2019 Circadian oscillations emerge from transcriptional and post-translational feedback loops. An important step in generating rhythmicity is the translocation of clock components into the nucleus, which is regulated in many cases by kinases.
Andrea Brenna +9 more
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Transcriptional Feedback Loops in the Caprine Circadian Clock System
Frontiers in Veterinary Science, 2022 The circadian clock system is based on interlocked positive and negative transcriptional and translational feedback loops of core clock genes and their encoded proteins.
Dengke Gao +23 more
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Age-Related Changes in the Expression of the Circadian Clock Protein PERIOD in Drosophila Glial Cells [PDF]
Frontiers in Physiology, 2018 Circadian clocks consist of molecular negative feedback loops that coordinate physiological, neurological, and behavioral variables into "circa" 24-h rhythms. Rhythms in behavioral and other circadian outputs tend to weaken during aging, as evident in progressive disruptions of sleep-wake cycles in aging organisms.
Dani M. Long, Jadwiga M. Giebultowicz
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