Results 41 to 50 of about 43,915 (298)

The Mammalian Circadian Clock Protein Period Counteracts Cryptochrome in Phosphorylation Dynamics of Circadian Locomotor Output Cycles Kaput (CLOCK) [PDF]

Journal of Biological Chemistry, 2014
The circadian transcription factor CLOCK exhibits a circadian oscillation in its phosphorylation levels. Although it remains unclear whether this phosphorylation contributes to circadian rhythm generation, it has been suggested to be involved in transcriptional activity, intracellular localization, and degradative turnover of CLOCK.
Ritsuko, Matsumura, Yoshiki, Tsuchiya, Isao, Tokuda, Takahiro, Matsuo, Miho, Sato, Koichi, Node, Eisuke, Nishida, Makoto, Akashi   +7 more
openaire   +2 more sources

Regulation of αENaC expression by the circadian clock protein Period 1 in mpkCCDc14 cells [PDF]

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2010
The epithelial sodium channel (ENaC) mediates the fine-tuned regulation of external sodium (Na) balance. The circadian clock protein Period 1 (Per1) is an aldosterone-induced gene that regulates mRNA expression of the rate-limiting alpha subunit of ENaC (αENaC).
VA Medical Center, Gainesville, FL, USA ( host institution ), Gumz, Michelle L. ( author ), Cheng, Kit-Yan ( author ), Lynch, I. Jeanette ( author ), Stow, Lisa R. ( author ), Greenlee, Megan M. ( author ), Cain, Brian D. ( author ), Wingo, Charles S. ( author )   +7 more
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Antibodies Against the Clock Proteins Period and Cryptochrome Reveal the Neuronal Organization of the Circadian Clock in the Pea Aphid [PDF]

Frontiers in Physiology, 2021
Circadian clocks prepare the organism to cyclic environmental changes in light, temperature, or food availability. Here, we characterized the master clock in the brain of a strongly photoperiodic insect, the aphid Acyrthosiphon pisum, immunohistochemically with antibodies against A.
Colizzi, Francesca Sara, Beer, Katharina, Cuti, Paolo, Deppisch, Peter, Martínez Torres, David, Yoshii, Taishi, Helfrich-Förster, Charlotte   +6 more
openaire   +5 more sources

The discoveries of molecular mechanisms for the circadian rhythm: The 2017 Nobel Prize in Physiology or Medicine

Biomedical Journal, 2018
Circadian clocks evolved to allow plants and animals to adapt their behaviors to the 24-hr change in the external environment due to the Earth's rotation.
Rong-Chi Huang
doaj   +1 more source

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders

Frontiers in Molecular Neuroscience, 2023
IntroductionCircadian rhythm maintains the sleep–wake cycle in biological systems. Various biological activities are regulated and modulated by the circadian rhythm, disruption of which can result in onset of diseases.
Md. Zubbair Malik, Mohammed Dashti, Yasmin Fatima, Arshad Channanath, Sumi Elsa John, R. K. Brojen Singh, Fahd Al-Mulla, Thangavel Alphonse Thanaraj   +7 more
doaj   +1 more source

Conditional circadian regulation of PHYTOCHROME A gene expression [PDF]

, 2001
The phytochrome photoreceptors and the circadian clock control many of the same developmental processes, in all organs and throughout the growth of Arabidopsis plants. Phytochrome A (phyA) provides light input signals to entrain the circadian clock.
Nagy, F, Hall, Anthony, Kozma-Bognár, L, Tóth, R, Millar, A J; id_orcid   +4 more
core   +1 more source

A global search for novel transcription factors impacting the Neurospora crassa circadian clock

G3: Genes, Genomes, Genetics, 2021
In order to identify new players modulating the circadian clock in the model Neurospora crassa, we adopted a reverse genetics strategy. Thus, we focused on transcription factors knockouts and crossed them to strains containing circadian luciferase ...
Felipe Muñoz-Guzmán, Valeria Caballero, Luis F Larrondo   +2 more
doaj   +1 more source

Non-alcoholic Fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. [PDF]

, 2014
Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear.
Mouralidarane Angelina, Chiara Saracino, Lucilla Poston (200809), Francesca Rappa, Ruma Saraswati, Fusai, Giuseppe, Paul D. Taylor (200813), Pazienza Valerio, Junpei Soeda, Carter, Rebeca, Jude A Oben, Angelina Mouralidarane (540950), Saraswati Ruma, Paul D Taylor, Mouralidarane, Angelina, Oben, JA, Saraswati, R, Fusai Giuseppe, Marco Novelli, Carter, R, Poston Lucilla, Marco Novelli (540954), Giuseppe Fusai (540955), Shuvra Ray (540951), Soeda, Junpei, Soeda, J, Pombo, J, Mouralidarane, A, Rappa, F, Ruma Saraswati (540953), Pazienza, Valerio, Novelli, Marco, Taylor Paul D., Joaquim Pombo (540952), Carter Rebeca, Saracino, C, Manlio Vinciguerra (287299), Saraswati, Ruma, Novelli, M, Oben, Jude A, Angelina Mouralidarane, Pombo, Joaquim, Fusai, G, RAPPA, Francesca, Saracino, Chiara, Novelli Marco, Rappa Francesca, Lucilla Poston, Francesca Rappa (55683), Manlio Vinciguerra, Rebeca Carter, Saracino Chiara, Poston, Lucilla; id_orcid, Pazienza, V, Vinciguerra, M, Joaquim Pombo, Rebeca Carter (540949), Ray Shuvra, Vinciguerra, Manlio, Vinciguerra, M. Oben J.A., Junpei Soeda (453348), Valerio Pazienza, Poston, L, Vinciguerra Manlio, Ray, S, Jude A. Oben (453352), Taylor, PD, Soeda Junpei, Giuseppe Fusai, Oben Jude A., Pombo Joaquim, Valerio Pazienza (174196), Taylor, Paul D; id_orcid, Chiara Saracino (540956), Ray, Shuvra, Shuvra Ray   +75 more
core   +1 more source

Temperature synchronization of the Drosophila circadian clock protein PERIOD is controlled by the TRPA channel PYREXIA [PDF]

Communications Biology, 2019
AbstractCircadian clocks are endogenous molecular oscillators that temporally organize behavioral activity thereby contributing to the fitness of organisms. To synchronize the fly circadian clock with the daily fluctuations of light and temperature, these environmental cues are sensed both via brain clock neurons, and by light and temperature sensors ...
Sanne Roessingh, Mechthild Rosing, Martina Marunova, Maite Ogueta, Rebekah George, Angelique Lamaze, Ralf Stanewsky   +6 more
openaire   +3 more sources

The hormonal Zeitgeber melatonin: role as a circadian modulator in memory processing [PDF]

, 2012
The neuroendocrine substance melatonin is a hormone synthesized rhythmically by the pineal gland under the influence of the circadian system and alternating light/dark cycles. Melatonin has been shown to have broad applications, and consequently becoming
Rawashdeh, Oliver, Erik Maronde, Maronde, Erik, Oliver eRawashdeh, Erik eMaronde, Oliver Rawashdeh   +5 more
core   +1 more source