Results 51 to 60 of about 356,744 (339)

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1

Proceedings of the National Academy of Sciences of the United States of America, 2011
Hyeong-Min Lee, Rongmin Chen, Hyukmin Kim, Jean‐Pierre Etchegaray, David R. Weaver, Choogon Lee   +5 more
openalex   +2 more sources

BBX19 fine-tunes the circadian rhythm by interacting with PSEUDO-RESPONSE REGULATOR proteins to facilitate their repressive effect on morning-phased clock genes

The Plant Cell, 2021
The core plant circadian oscillator is composed of multiple interlocked transcriptional–translational feedback loops, which synchronize endogenous diel physiological rhythms to the cyclic changes of environmental cues.
Li Yuan, Yingjun Yu, Mingming Liu, Yang Song, Hong-ming Li, Junqiu Sun, Qiao Wang, Qiguang Xie, Lei Wang, Xiaodong Xu   +9 more
semanticscholar   +1 more source

USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock. [PDF]

PLoS ONE, 2016
Mammalian Cryptochromes, CRY1 and CRY2, function as principal regulators of a transcription-translation-based negative feedback loop underlying the mammalian circadian clockwork.
Arisa Hirano, Tomoki Nakagawa, Hikari Yoshitane, Masaaki Oyama, Hiroko Kozuka-Hata, Darin Lanjakornsiripan, Yoshitaka Fukada   +6 more
doaj   +1 more source

mTOR signaling regulates central and peripheral circadian clock function. [PDF]

PLoS Genetics, 2018
The circadian clock coordinates physiology and metabolism. mTOR (mammalian/mechanistic target of rapamycin) is a major intracellular sensor that integrates nutrient and energy status to regulate protein synthesis, metabolism, and cell growth.
Chidambaram Ramanathan, Nimish D Kathale, Dong Liu, Choogon Lee, David A Freeman, John B Hogenesch, Ruifeng Cao, Andrew C Liu   +7 more
doaj   +1 more source

Tuning the circadian period of cyanobacteria up to 6.6 days by the single amino acid substitutions in KaiC

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Circadian clocks, biological oscillators with temperature-compensated periods close to 24 h, enhance fitness in Earth’s daily cycle. Although many circadian period mutants have helped to elucidate the circadian clock mechanism, the tuning ...
Kumiko Ito-Miwa, Y. Furuike, S. Akiyama, T. Kondo   +3 more
semanticscholar   +1 more source

Intrinsic disorder is an essential characteristic of components in the conserved circadian circuit

Cell Communication and Signaling, 2020
Introduction The circadian circuit, a roughly 24 h molecular feedback loop, or clock, is conserved from bacteria to animals and allows for enhanced organismal survival by facilitating the anticipation of the day/night cycle.
Jacqueline F. Pelham, Jay C. Dunlap, Jennifer M. Hurley   +2 more
doaj   +1 more source

Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock. [PDF]

PLoS ONE, 2011
Circadian clocks coordinate the timing of important biological processes. Interconnected transcriptional and post-translational feedback loops based on a set of clock genes generate and maintain these rhythms with a period of about 24 hours.
Isabelle Schmutz, Sabrina Wendt, Anna Schnell, Achim Kramer, Isabelle M Mansuy, Urs Albrecht   +5 more
doaj   +1 more source

The Na+/H+ antiporter SALT OVERLY SENSITIVE 1 regulates salt compensation of circadian rhythms by stabilizing GIGANTEA in Arabidopsis

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance The circadian clock is an endogenous molecular timekeeper that coordinates biological rhythms of physiological and developmental processes in living organisms.
J. Cha, Jeongsik Kim, Song Yi Jeong, Gyeong-Im Shin, M. Ji, J. Hwang, L. Khaleda, Xueji Liao, Gyeongik Ahn, H. Park, Dong Young Kim, J. M. Pardo, Sang Yeol Lee, D. Yun, D. E. Somers, Woe-Yeon Kim   +15 more
semanticscholar   +1 more source

The proteomic landscape of the suprachiasmatic nucleus clock reveals large-scale coordination of key biological processes. [PDF]

PLoS Genetics, 2014
The suprachiasmatic nucleus (SCN) acts as the central clock to coordinate circadian oscillations in mammalian behavior, physiology and gene expression.
Cheng-Kang Chiang, Neel Mehta, Abhilasha Patel, Peng Zhang, Zhibin Ning, Janice Mayne, Warren Y L Sun, Hai-Ying M Cheng, Daniel Figeys   +8 more
doaj   +1 more source

Expression and Purification of Cyanobacterial Circadian Clock Protein KaiC and Determination of Its Auto-phosphatase Activity

Bio-Protocol, 2017
Circadian rhythms are biological processes displaying an endogenous oscillation with a period of ~24 h. They allow organisms to anticipate and get prepared for the environmental changes caused mainly by the rotation of Earth. Circadian rhythms are driven
Qiang Chen, Lingling Yu, Xiao Tan , Sen Liu   +3 more
doaj   +1 more source