Results 61 to 70 of about 231,424 (276)

Overall Dynamic Constitutive Relations of Micro-structured Elastic Composites

, 2011
A method for homogenization of a heterogeneous (finite or periodic) elastic composite is presented. It allows direct, consistent, and accurate evaluation of the averaged overall frequency-dependent dynamic material constitutive relations.
Amirkhizi, Ankit Srivastava, Bakhvalov, Bensoussan, Beran, Diener, Eshelby, Hardiman, Hashin, Hashin, Hill, Iwakuma, Milton, Nemat-Nasser, Nemat-Nasser, Nemat-Nasser, Nemat-Nasser, Nemat-Nasser, Nemat-Nasser, Rytov, Sia Nemat-Nasser, Smith, Torquato, Willis, Willis, Willis, Willis, Willis, Willis   +28 more
core   +1 more source

Stress impairs the efficacy of immune stimulation by CpG-C: Potential neuroendocrine mediating mechanisms and significance to tumor metastasis and the perioperative period [PDF]

Brain, Behavior, and Immunity, 2016
We recently reported that immune stimulation can be compromised if animals are simultaneously subjected to stressful conditions. To test the generalizability of these findings, and to elucidate neuroendocrine mediating mechanisms, we herein employed CpG-C, a novel TLR-9 immune-stimulating agent.
Shamgar Ben-Eliyahu, Lee Shaashua, L. Sorski, Pini Matzner, Gayle G. Page, Rivka Melamed, Yael Goldfarb, Ella Rosenne, B. Levi   +8 more
openaire   +2 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Correlating Cell Shape and Cellular Stress in Motile Confluent Tissues

, 2017
Collective cell migration is a highly regulated process involved in wound healing, cancer metastasis and morphogenesis. Mechanical interactions among cells provide an important regulatory mechanism to coordinate such collective motion.
Bi, Dapeng, Czajkowski, Michael, Manning, M. Lisa, Marchetti, M. Cristina, Merkel, Matthias, Yang, Xingbo   +5 more
core   +1 more source

Local damage in a 5-harness satin weave composite under static tension, part II: meso-FE modelling [PDF]

, 2010
International audienceThis study forms the second part of a paper on the local damage analysis in a thermo-plastic 5-harness satin weave composite under uni-axial static tensile load.
Daggumati, Subbareddy, Degrieck, Joris, Lomov, SV, Van Paepegem, Wim, Verpoest, i, Xu, J   +5 more
core   +4 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Fatigue strength and durability analysis by normalised equivalent stress functionals [PDF]

, 2003
Generalised fatigue durability diagrams are considered for a material under multi-axial loading given by a (non-regularly) oscillating function of time.
Mikhailov, SE, Namestnikova, IV
core   +1 more source

Topological modes bound to dislocations in mechanical metamaterials

, 2015
Mechanical metamaterials are artificial structures with unusual properties, such as negative Poisson ratio, bistability or tunable vibrational properties, that originate in the geometry of their unit cell.
A Stern, BG Chen, Bryan Gin-ge Chen, C Calladine, CL Kane, E Prodan, Jayson Paulose, JC Maxwell, JCY Teo, K Sun, M Schenk, S Babaee, S Shan, T Tachi, V Juričić, V Vitelli, Vincenzo Vitelli, Y Ran, ZY Wei   +18 more
core   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Micromechanical response of fibre-reinforced materials using the boundary element technique [PDF]

, 2003
The Boundary Element Method (BEM) and the Embedded Cell Approach (ECA) have been used to analyse the effects of constituent material properties and fibre spatial distribution on the localised behaviour of a transversely loaded, unidirectional fibre ...
Henshall, JL, Knight, MG, Wrobel, LC
core   +1 more source