Results 161 to 170 of about 22,276 (328)

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

lncRNA CYTOR Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating SOX11 via Sponging miR-6512-3p [PDF]

, 2023
Shaoqin Tu, Yihua Chen, Yi Feng, Zhili Kuang, Yuxuan Wang, Lin Chen, Zhihui Mai, Jiaming Wei, Sai Zhang, Yiting Shao, Hong Ai, Zheng Chen   +11 more
openalex   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Evaluation of autologous periodontal stem cells niche in the treatment of periodontal intrabony defects: A split-mouth randomized controlled trial

Journal of Indian Society of Periodontology
Background: Regeneration of the lost periodontium requires an abundant supply of the desired cell. Stem cells can provide progenitor cells at the target location; however stem cell therapy is technique sensitive.
Hungyo Chanreiphy, Vineeta Gupta, Kharidhi Laxman Vandana, Varsha Goswami, Bhumika Jhawar, V. Vinitha   +5 more
doaj   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

tRNA Profiling of Mesenchymal Stem Cell Exosome [PDF]

, 2018
Background: Exosomes have great potential in regenerative medicine through the transfer of their bioactive cargos, such as RNA. tRF RNA and tiRNA are tRNAderived non-coding RNA.
San, Khin MiMi
core   +1 more source

MicroRNA-21 regulates Osteogenic Differentiation of Periodontal Ligament Stem Cells by targeting Smad5 [PDF]

, 2017
Fulan Wei, Shuangyan Yang, Qingyuan Guo, Xin Zhang, Dapeng Ren, Tao Lv, Xin Xu   +6 more
openalex   +1 more source

Sodium butyrate inhibits osteogenesis in human periodontal ligament stem cells by suppressing smad1 expression [PDF]

, 2022
Jingyi Hou, Junji Xu, Yi Liu, Haiping Zhang, Sihan Wang, Jiao Yao, Lijia Guo, Song Li   +7 more
openalex   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

Exosomes and exosome composite scaffolds in periodontal tissue engineering

Frontiers in Bioengineering and Biotechnology
Promoting complete periodontal regeneration of damaged periodontal tissues, including dental cementum, periodontal ligament, and alveolar bone, is one of the challenges in the treatment of periodontitis.
Tingyu Wang, Tingyu Wang, Yanxing Zhou, Wenwen Zhang, Yuanye Xue, Ziteng Xiao, Yanfang Zhou, Yanfang Zhou, Xinsheng Peng, Xinsheng Peng   +9 more
doaj   +1 more source