Results 11 to 20 of about 22,276 (328)

Periodontal tissue stem cells and mesenchymal stem cells in the periodontal ligament

Japanese Dental Science Review, 2022
Periodontal tissue stem cells, which play a crucial role in maintaining the homeostasis of periodontal tissues, are found in the periodontal ligament (PDL).
Tomoaki Iwayama, Hiromi Sakashita, Masahide Takedachi, Shinya Murakami   +3 more
doaj   +3 more sources

Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis [PDF]

Stem Cells, 2020
AbstractLoss of tissue attachment as a consequence of bacterial infection and inflammation represents the main therapeutic target for the treatment of periodontitis. Cementoblasts, the cells that produce the mineralized tissue, cementum, that is responsible for connecting the soft periodontal tissue to the tooth, are a key cell type for maintaining ...
Jing Zhao, Louis Faure, Igor Adameyko, Paul T. Sharpe   +3 more
openalex   +4 more sources

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis [PDF]

Frontiers in Cell and Developmental Biology, 2021
Periodontitis is an immune inflammatory disease that leads to progressive destruction of bone and connective tissue, accompanied by the dysfunction and even loss of periodontal ligament stem cells (PDLSCs). Pyroptosis mediated by gasdermin-D (GSDMD) participates in the pathogenesis of inflammatory diseases.
Qin Chen, Xingguang Liu, Dingyu Wang, Jisi Zheng, Lu Chen, Qianyang Xie, Xiaohan Liu, Sujuan Niu, Guanlin Qu, Jianfeng Lan, Jing Li, Chi Yang, Duohong Zou   +12 more
openaire   +3 more sources

Therapeutic potential of periodontal ligament stem cells

World Journal of Stem Cells, 2021
Inflammatory periodontal disease known as periodontitis is one of the most common conditions that affect human teeth and often leads to tooth loss. Due to the complexity of the periodontium, which is composed of several tissues, its regeneration and subsequent return to a homeostatic state is challenging with the therapies currently available. Cellular
Queiroz, Aline, Albuquerque-Souza, Emmanuel, Gasparoni, Leticia Miquelitto, de França, Bruno Nunes, Pelissari, Cibele, Trierveiler, Marília, Holzhausen, Marinella   +6 more
openaire   +2 more sources

Stem cells in the periodontal ligament [PDF]

Oral Diseases, 2006
The ability to identify and manipulate stem cells has been a significant advancement in regenerative medicine and has contributed to the development of tissue engineering‐based clinical therapies. Difficulties associated with achieving predictable periodontal regeneration, means that novel techniques such as tissue engineering need to be developed in ...
Ivanovski, S., Gronthos, S., Shi, S., Bartold, P.   +3 more
openaire   +3 more sources

Periodontal Ligament Stem Cells: Current Knowledge and Future Perspectives

Stem Cells and Development, 2019
Teeth represent a fascinating area of study in regenerative medicine, because of their unique and complex developmental origin. Several types of mesenchymal stem cells (MSCs) have been characterized in the oral cavity, and those derived from the periodontal ligament (PDL) first isolated by our group in 2005, can be expanded in a xeno-free medium ...
Oriana Trubiani, Jacopo Pizzicannella, Sergio Caputi, Marco Marchisio, Emanuela Mazzon, Roberto Paganelli, Alessia Paganelli, Francesca Diomede   +7 more
openalex   +5 more sources

Periodontal Ligament Stem Cells for Periodontal Regeneration [PDF]

Current Oral Health Reports, 2015
Periodontal tissue is susceptible to chronic periodontal disease, which results in irreversible tissue destruction. Adult stem cells can be obtained from the periodontal ligament of the periodontium. Stem cells from the periodontal ligament (PDLSCs) are promising for periodontal regeneration because they can undergo guided differentiation under ...
In Seok Song, Yoon Sic Han, Joo-Hee Lee, Soyoun Um, Hui Young Kim, Byoung Moo Seo   +5 more
openaire   +1 more source

Impact of Magnetic Stimulation on Periodontal Ligament Stem Cells [PDF]

International Journal of Molecular Sciences, 2021
The aim of this study was to evaluate the effect of a time-dependent magnetic field on the biological performance of periodontal ligament stem cells (PDLSCs). A Western blot analysis and Alamar Blue assay were performed to investigate the proliferative capacity of magnetically stimulated PDLSCs (PDLSCs MAG) through the study of the MAPK cascade (p-ERK1/
Peluso V, Rinaldi L, Russo T, Oliviero O, Di Vito A, Garbi C, Giudice A, De Santis R, Gloria A, D'anto V   +9 more
openaire   +4 more sources

Astragaloside IV Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells via Activating PI3K/AKT/eNOS/NO Signaling Pathway: In vitro and in vivo Study. [PDF]

Drug Des Devel Ther
Song Y, Hu J, Yang P, Zhang Y, Wu Z, Chen S, Zhang J.   +6 more
europepmc   +3 more sources

Periodontal Regeneration Using Periodontal Ligament Stem Cell-Transferred Amnion [PDF]

Tissue Engineering Part A, 2013
Periodontal disease is characterized by the destruction of tooth supporting tissues. Regeneration of periodontal tissues using ex vivo expanded cells has been introduced and studied, although appropriate methodology has not yet been established. We developed a novel cell transplant method for periodontal regeneration using periodontal ligament stem ...
Kengo, Iwasaki, Motohiro, Komaki, Naoki, Yokoyama, Yuichi, Tanaka, Atsuko, Taki, Izumi, Honda, Yasuyuki, Kimura, Masaki, Takeda, Keiko, Akazawa, Shigeru, Oda, Yuichi, Izumi, Ikuo, Morita   +11 more
openaire   +2 more sources