Results 21 to 30 of about 5,468,047 (208)
Signalling pathways in the osteogenic differentiation of periodontal ligament stem cells
Open Life Sciences, 2023 Periodontal ligament stem cells (PDLSCs) have multidirectional differentiation potential and self-renewal abilities and are important seed cells for the regenerative repair of periodontal tissues.
Liuyu Ru, Bowen Pan, Ji-Wei Zheng
semanticscholar +1 more source
Saudi Dental Journal, 2021 Mesenchymal stem cells (MSCs) are extensively used in tissue regenerative procedures. One source of MSCs is the periodontal ligament (PDL) of teeth. Isolation of MSCs from extracted teeth is reasonably simple, being less invasive and presenting fewer ...
Spoorthi Ravi Banavar +6 more
doaj +1 more source
Frontiers in Chemistry, 2022 This study aimed to explore the effects of exosomes derived from human gingival mesenchymal stem cells (GMSC-Exo) on the inflammatory response of periodontal ligament stem cells (PDLSCs) in an inflammatory microenvironment in order to restore the ...
Jia-Yao Sun +7 more
semanticscholar +1 more source
Dental regenerative therapy targeting sphingosine-1-phosphate (S1P) signaling pathway in endodontics
Japanese Dental Science Review, 2020 The establishment of regenerative therapy in endodontics targeting the dentin-pulp complex, cementum, periodontal ligament tissue, and alveolar bone will provide valuable information to preserve teeth.
Etsuko Matsuzaki +3 more
doaj +1 more source
Periodontal ligament stem cells as a promising therapeutic target for neural damage
Stem cell research & therapeutics, 2022 Background The damaged neuronal cells of adult mammalian lack the regenerative ability to replace the neuronal connections. Periodontal ligament stem cells (PDLSCs) are the promising source for neuroregenerative applications that can improve the injured ...
Fariba Mohebichamkhorami +6 more
semanticscholar +1 more source
Journal of Tissue Engineering, 2019 EphrinB2, a membrane protein regulating bone homeostasis, has been demonstrated to induce osteogenic gene expression in periodontal ligament fibroblasts.
Penglai Wang +6 more
doaj +1 more source
Frontiers in Immunology, 2020 Maresin-1 (MaR1) and Resolvin E1 (RvE1) are specialized pro-resolving lipid mediators (SPMs) that regulate inflammatory processes. We have previously demonstrated the hard and soft tissue regenerative capacity of RvE1 in an in vivo model of the ...
Emmanuel Albuquerque-Souza +10 more
doaj +1 more source
eJournal of Oral Maxillofacial Research, 2018 Objectives: The aim of this study was to assess the interaction of a bioactive glass scaffold with cells derived from dental pulp, dental follicle and periodontal ligament. Material and Methods: Impacted third molars were surgically removed from three
Gregorio Raspini +4 more
doaj +1 more source
Stem cell research & therapeutics, 2022 Periodontal ligament stem cells (PDLSCs) are the ideal seed cells for periodontal tissue regeneration. It is well established that persistent inflammation significantly impairs the osteogenic differentiation capability of PDLSCs.
Xin-Yuan Zhao +3 more
semanticscholar +1 more source
Comparison of periodontal ligament and gingiva-derived mesenchymal stem cells for regenerative therapies. [PDF]
, 2017 Objectives: Tissue-engineering therapies using undifferentiated mesenchymal cells (MSCs) from intra-oral origin have been tested in experimental animals. This experimental study compared the characteristics of undifferentiated mesenchymal stem cells from
Santamaría, Silvia +3 more
core +1 more source