Results 11 to 20 of about 5,468,047 (208)

Influence of Extracellular Matrix Components on the Differentiation of Periodontal Ligament Stem Cells in Collagen I Hydrogel

Cells, 2023
Regeneration of periodontal tissues requires an integrated approach to the restoration of the periodontal ligament, cementum, and alveolar bone surrounding the teeth.
A. Ivanov, A. Kuznetsova, O. Popova, T. I. Danilova, A. Latyshev, O. Yanushevich   +5 more
semanticscholar   +2 more sources

Human Umbilical Cord Mesenchymal Stem Cells: Current Literature and Role in Periodontal Regeneration

Cells, 2022
Periodontal disease can cause irreversible damage to tooth-supporting tissues such as the root cementum, periodontal ligament, and alveolar bone, eventually leading to tooth loss.
Muhammad Saad Shaikh, Zara Shahzad, Esraa Abdulgader Tash, Omer Sefvan Janjua, Muhammad Ikram Khan, Muhammad Sohail Zafar   +5 more
doaj   +2 more sources

Erythropoietin receptor signal is crucial for periodontal ligament stem cell-based tissue reconstruction in periodontal disease

Scientific Reports
Alveolar bone loss caused by periodontal disease eventually leads to tooth loss. Periodontal ligament stem cells (PDLSCs) are the tissue-specific cells for maintaining and repairing the periodontal ligament, cementum, and alveolar bone.
MHD. Fouad Zakaria, Soichiro Sonoda, Hiroki Kato, Lan Ma, Norihisa Uehara, Yukari Kyumoto-Nakamura, M. Majd Sharifa, Liting Yu, Lisha Dai, Erika Yamauchi-Tomoda, Reona Aijima, Haruyoshi Yamaza, Fusanori Nishimura, Takayoshi Yamaza   +13 more
doaj   +3 more sources

Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells

Cellular & Molecular Biology Letters, 2023
Background The preference for glucose oxidative mode has crucial impacts on various physiological activities, including determining stem cell fate. External mechanical factors can play a decisive role in regulating critical metabolic enzymes and pathways
Zi-Jie Zhang, Shu-Yue Cui, Ya-Jing Fu, Jixiao Wang, Jia-Ni Liu, Fu-Lan Wei   +5 more
semanticscholar   +1 more source

Effects of tension on mitochondrial autophagy and osteogenic differentiation of periodontal ligament stem cells

Cell Proliferation, 2023
This study aimed to explore the osteogenic ability and mitochondrial autophagy of periodontal ligament stem cells (PDLSCs) under cyclic tensile stress (CTS). Primary PDLSCs were isolated from the periodontal membrane and cultured by passage. Alizarin red
X. Shao, Zhong Hu, Hui-Qin Su, Yu-Zhong Wang, Yun-Feng Lin   +4 more
semanticscholar   +1 more source

Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6

Scientific Reports, 2023
Periodontal ligament stem cells (PDLSCs) play a significant role on periodontal tissue and alveolar bone homeostasis. During inflammation, interleukin (IL)-6 serves as one of key cytokine players controlling tissue reaction as well as alveolar bone ...
M. Purwaningrum, C. Giachelli, T. Osathanon, Sirirat Rattanapuchpong, Chenphop Sawangmake   +4 more
semanticscholar   +1 more source

NADPH-dependent ROS accumulation contributes to the impaired osteogenic differentiation of periodontal ligament stem cells under high glucose conditions

Frontiers in Endocrinology, 2023
Diabetes mellitus is an established risk factor for periodontal disease that can aggravate the severity of periodontal inflammation and accelerate periodontal destruction. The chronic high glucose condition is a hallmark of diabetes-related pathogenesis,
Yi-lin Zhang, Ying An, Li-Juan Sun, Hong-Lei Qu, Xuan Li, Xiaoyong He, Rui-Xin Wu, Fa-Ming Chen, B. Tian, Yuan Yin   +9 more
semanticscholar   +1 more source

Cultivation and expansion of mesenchymal stem cells from human gingival tissue and periodontal ligament in different culture media

Dental Journal, 2021
Background: Gingival tissue and periodontal ligament act as sources of mesenchymal stem cells (MSCs) that play a vital role in periodontal regeneration, but they both have limitations for cell availability.
Banun Kusumawardani, Dwi Merry Christmarini Robin, Endah Puspitasari, Irma Josefina Savitri, Dea Ajeng Pravita Suendi   +4 more
doaj   +1 more source

GRP78 PROMOTES THE OSTEOGENIC AND ANGIOGENIC RESPONSE IN PERIODONTAL LIGAMENT STEM CELLS

European Cells & Materials, 2023
Periodontitis is a progressive disease that ultimately leads to bone and tooth loss. A major consequence of periodontal disease is the inability to regain lost bone in the periodontium.
A. Merkel, Y. Chen, C. Villani, A. George   +3 more
semanticscholar   +1 more source

Tenomodulin expression in the periodontal ligament enhances cellular adhesion. [PDF]

, 2013
Tenomodulin (Tnmd) is a type II transmembrane protein characteristically expressed in dense connective tissues such as tendons and ligaments. Its expression in the periodontal ligament (PDL) has also been demonstrated, though the timing and function ...
Shukunami, Chisa, Nakajima, Keiji, Chisa Shukunami (401372), Hojo, Hironori, Chung, Ung-Il, Chisa Shukunami, Keiji Nakajima (28049), Denitsa Docheva (385570), Fumiko Yano, Yuji Hiraki, Nobuyuki Shimohata (401370), Denitsa Docheva, Yuske Komiyama, Hironori Hojo (401371), Ung-il Chung (34003), Komiyama, Yuske, Shinsuke Ohba, Fumiko Yano (266988), Yuji Hiraki (401373), Tsuyoshi Takato, Hiraki, Yuji, Ung-Il Chung, Yuske Komiyama (401369), Shimohata, Nobuyuki, Docheva, Denitsa, Keiji Nakajima, Shinsuke Ohba (33998), Takato, Tsuyoshi, Nobuyuki Shimohata, Yano, Fumiko, Tsuyoshi Takato (379959), Ohba, Shinsuke, Hironori Hojo, Hojo Hironori, Takato Tsuyoshi, Komiyama Yuske, Shukunami Chisa, Shimohata Nobuyuki, Nakajima Keiji, Chung Ung-il, Docheva Denitsa, Yano Fumiko, Ohba Shinsuke, Hiraki Yuji   +43 more
core   +1 more source