Results 191 to 200 of about 12,081 (284)

Human periodontal ligament stem cells-derived small extracellular vesicles mitigate periodontitis by regulating macrophage pyroptosis. [PDF]

J Transl Med
Yang C, Wang W, Feng C, Xu S, Zhang L, Wang Y, Xing X, Ji Q.   +7 more
europepmc   +1 more source

Immunomodulatory Mechanism of Baiyaojian Decoction on Periodontitis: Network Pharmacology, Single‐Cell RNA Sequencing and Molecular Docking

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Periodontitis is one of the most common oral inflammatory diseases. Baiyaojian decoction, known for its prominent immunomodulatory and anti‐inflammatory properties, shows significant potential in treating periodontitis, though its molecular mechanisms remain unknown. The active ingredients and therapeutic targets were determined by integrating
Bing‐jun Chen, Ming‐ming Li, Zhao‐yu Zheng, Wen‐qin Jin, Zhao Jin, Yu‐ling Zuo   +5 more
wiley   +1 more source

Calpain-1 Potentiates Periodontal Regeneration via PHLPP1-ERK-Driven Osteogenesis in Periodontal Ligament Stem Cells. [PDF]

Int Dent J
Li Y, Yang B, Mei Z, Deng P, Fu T, Li J.
europepmc   +1 more source

Characterising the Periodontal Granulation Tissue Using scRNAseq

Journal of Clinical Periodontology, Volume 53, Issue 2, Page 308-320, February 2026.
ABSTRACT Aim To investigate the cellular composition and molecular mechanisms of periodontal granulation tissue formation using single‐cell RNA sequencing (scRNA‐seq), aiming to enhance the understanding of periodontal disease pathogenesis and identify potential targets for regenerative therapies.
Wentao Zhu, Kathy Fung, Pawan Dhami, Paul Sharpe, Jan Krivanek, Luigi Nibali, Cheng Zhang, Vitor C. M. Neves   +7 more
wiley   +1 more source

Exendin-4 Reduces Senescence of Inflammation-Induced Periodontal Ligament Stem Cells Through SIRT1/Notch1 Signaling. [PDF]

Stem Cells Int
Xu Y, Zheng J, Liu M, Fu Z, Wang P.
europepmc   +1 more source

Is Obesity a Risk Factor for Periodontitis? A Systematic Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 2, February 2026.
ABSTRACT Objectives This study aims at reviewing available evidence on the relationship between obesity and periodontitis, focusing on whether obesity is a risk factor for the development and progression of periodontal disease. Materials and Methods This systematic review and meta‐analysis were reported in accordance with the PRISMA guidelines ...
Fariba Esperouz, Domenico Ciavarella, Claudio Di Gioia, Gaetano Serviddio, Mauro Lorusso, Lucio Lo Russo   +5 more
wiley   +1 more source

Role of SIRT6 in Chronic Periodontitis and Osteogenic Differentiation of Periodontal Ligament Stem Cells. [PDF]

Int Dent J
Guo H, Liu R, Xu H, Pan J, Gu H.
europepmc   +1 more source

Similar Individual Serum Levels of MCP‐1, TNF‐α, and IL‐6 From Periodontitis Patients Before and 1 Year After Treatment

Scandinavian Journal of Immunology, Volume 103, Issue 2, February 2026.
Periodontitis patients before and 1 year present with similar levels of MCP‐1, TNF‐α, and IL‐6, cytokine equilibrium. MCP‐1, TNF‐α, and IL‐6 are not correlated per individual, meaning that some individuals may present with relatively high levels of one of the cytokines with lower levels of the other cytokines or cytokine signature.
Teun J. de Vries, Sergio Bizzarro, Irene Di Ceglie, Doran Y. Sol, Peter L. E. M. van Lent, Ton Schoenmaker   +5 more
wiley   +1 more source

Jaw-specific differential kinase activity profiles in human periodontal ligament stem cells under mechanical compression. [PDF]

Stem Cell Res Ther
Niederau C, Maas SL, van der Vorst EPC, Schurgers LJ, Shi Y, Hölzle F, Wolf M, Craveiro RB.   +7 more
europepmc   +1 more source

The role of amino bisphosphonates zoledronate and alendronate in shaping immunomodulatory profile and angiogenic potential of human periodontal ligament stem cells. [PDF]

PLoS One
Bria J, Chiarella E, Sovereto J, Baudi F, Greco M, Foti DP, Giudice A, Di Vito A.   +7 more
europepmc   +1 more source