Results 21 to 30 of about 22,276 (328)

Allogeneic Periodontal Ligament Stem Cell Therapy for Periodontitis in Swine     [PDF]

Stem Cells, 2010
AbstractPeriodontitis is one of the most widespread infectious diseases in humans. It is the main cause of tooth loss and associated with a number of systemic diseases. Until now, there is no appropriate method for functional periodontal tissue regeneration. Here, we establish a novel approach of using allogeneic periodontal ligament stem cells (PDLSCs)
Ding, Gang, Liu, Yi, Wang, Wei, Wei, Fulan, Liu, Dayong, Fan, Zhipeng, An, Yunqing, Zhang, Chunmei, Wang, Songlin   +8 more
openaire   +2 more sources

Conditioned Medium from Periodontal Ligament Stem Cells Enhances Periodontal Regeneration [PDF]

Tissue Engineering Part A, 2017
Periodontal disease is one of the most common infectious diseases in adults and is characterized by the destruction of tooth-supporting tissues. Mesenchymal stem cells (MSCs) comprise the mesoderm-originating stem cell population, which has been studied and used for cell therapy.
Mizuki, Nagata, Kengo, Iwasaki, Keiko, Akazawa, Motohiro, Komaki, Naoki, Yokoyama, Yuichi, Izumi, Ikuo, Morita   +6 more
openaire   +2 more sources

Cultivation and expansion of mesenchymal stem cells from human gingival tissue and periodontal ligament in different culture media

Dental Journal, 2021
Background: Gingival tissue and periodontal ligament act as sources of mesenchymal stem cells (MSCs) that play a vital role in periodontal regeneration, but they both have limitations for cell availability.
Banun Kusumawardani, Dwi Merry Christmarini Robin, Endah Puspitasari, Irma Josefina Savitri, Dea Ajeng Pravita Suendi   +4 more
doaj   +1 more source

Periodontal Ligament Stem Cells [PDF]

, 2011
Millions of people experience consequential tooth loss related to irretrievable damage of the periodontium caused by deep caries, severe periodontal diseases or irreversible trauma, resulting in a decreased quality of life. Hence, dental scientists have focused much attention on tissue engineering techniques in an effort to address this condition.
Maeda, Hidefumi, Wada, Naohisa, Fujii, Shinsuke, Tomokiyo, Atsushi, Akamine, Akifumi   +4 more
openaire   +2 more sources

Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration [PDF]

Stem Cell Research & Therapy, 2019
AbstractBackgroundThe inflammation and regeneration process may be accompanied by the shift in the M1/M2 polarization of macrophages to adapt to extracellular signals. How the macrophages responded to the altered immunological environment in the periodontal niche after stem cell transplantation has never been explored.
Jiaying Liu, Bin Chen, Jun Bao, Yangheng Zhang, Lang Lei, Fuhua Yan   +5 more
openaire   +3 more sources

Improved methods for detection of β-galactosidase (lacZ) activity in hard tissue [PDF]

, 2012
The ß-galactosidase gene (lacZ) of Escherichia coli is widely used as a reporter gene. The expression of lacZ can be detected by enzyme-based histochemical staining using chromogenic substrates such as 5-bromo-4-chloro-3-indolyl-ß-D: -galactoside (X-gal).
A Aguzzi, A Cho, A Shimada, Akemi Shimada, Akira Nifuji, B Bolon, B Brachvogel, B Brachvogel, C Cui, C Pereira, D Hannouche, D Houzelstein, DJ Kurz, Ernst Pöschl, F Lézot, I Diamond, J Sanchez-Ramos, JR Murti, JR Sanes, Kazuhisa Nakashima, Koichiro Komatsu, L Gioglio, M Takahashi, P Avé, P Bell, PC Lekic, PR Odgren, W Ma   +27 more
core   +2 more sources

Dental regenerative therapy targeting sphingosine-1-phosphate (S1P) signaling pathway in endodontics

Japanese Dental Science Review, 2020
The establishment of regenerative therapy in endodontics targeting the dentin-pulp complex, cementum, periodontal ligament tissue, and alveolar bone will provide valuable information to preserve teeth.
Etsuko Matsuzaki, Masahiko Minakami, Noriyoshi Matsumoto, Hisashi Anan   +3 more
doaj   +1 more source

Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]

, 2017
Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna, Marrelli, Massimo, Pacifici, Andrea, Pacifici, Luciano, Paduano, Francesco, Palmieri, Francesca, Tatullo, Marco   +6 more
core   +2 more sources

EphrinB2 regulates osteogenic differentiation of periodontal ligament stem cells and alveolar bone defect regeneration in beagles

Journal of Tissue Engineering, 2019
EphrinB2, a membrane protein regulating bone homeostasis, has been demonstrated to induce osteogenic gene expression in periodontal ligament fibroblasts.
Penglai Wang, Wen Wang, Tengyu Geng, Yi Liu, Shaoyue Zhu, Zongxiang Liu, Changyong Yuan   +6 more
doaj   +1 more source

Maresin-1 and Resolvin E1 Promote Regenerative Properties of Periodontal Ligament Stem Cells Under Inflammatory Conditions

Frontiers in Immunology, 2020
Maresin-1 (MaR1) and Resolvin E1 (RvE1) are specialized pro-resolving lipid mediators (SPMs) that regulate inflammatory processes. We have previously demonstrated the hard and soft tissue regenerative capacity of RvE1 in an in vivo model of the ...
Emmanuel Albuquerque-Souza, Emmanuel Albuquerque-Souza, Fabian Schulte, Fabian Schulte, Tsute Chen, Markus Hardt, Markus Hardt, Hatice Hasturk, Thomas E. Van Dyke, Marinella Holzhausen, Alpdogan Kantarci   +10 more
doaj   +1 more source