Results 51 to 60 of about 5,468,047 (208)

Metformin combats high glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells via inhibition of the NPR3-mediated MAPK pathway

Stem cell research & therapeutics, 2022
Background High glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells (PDLSCs) has long been a challenge to periodontal regeneration for diabetic individuals.
Yi-lin Zhang, Fen Liu, Zhi-Bang Li, Xiao-Tao He, Xuan Li, Rui-Xin Wu, Hai-Hua Sun, Shao-Hua Ge, Fa-Ming Chen, Ying An   +9 more
semanticscholar   +1 more source

The Role of MicroRNA in the Behaviour of Periodontal Ligament Stem Cells and Stem Cells from the Apical Papilla: A Systematic Review. [PDF]

Stem Cell Rev Rep
This registration contains the protocol for the systematic review entitled "The role of microRNA in the behaviour of periodontal ligament stem cells and stem cells from the apical papilla: a systematic review"
Sanz JL, Forner L, López-García S, Rodríguez-Lozano FJ, Santos JM, Folguera S, López-Ginés C, Monleón D.   +7 more
europepmc   +3 more sources

Management of endo-perio lesion with autologous stem cell therapy

Saudi Journal of Oral Sciences
The objective of periodontal therapy is the regeneration of tooth-supporting tissues. Various treatment modalities, such as the use of bone grafting materials, guided tissue regeneration, and delivery of enamel matrix derivatives or growth factors, are ...
Vangara Aditya, Kharidhi Laxman Vandana
doaj   +1 more source

Effect of mechanical stimulation on the differentiation of stem cells in periodontal bone tissue engineering

口腔疾病防治, 2021
Currently, cell transplantation in combination with scaffold materials are one of the main strategies in periodontal bone tissue engineering. In periodontal bone tissues, the stiffness and spatial structure of tissues such as alveolar bone and cementum ...
LI Tianle, CHANG Xinnan, QIU Xutong, FU Di, ZHANG Tao   +4 more
doaj   +1 more source

The cytoskeleton dynamics-dependent LINC complex in periodontal ligament stem cells transmits mechanical stress to the nuclear envelope and promotes YAP nuclear translocation

Stem cell research & therapeutics
Periodontal ligament stem cells (PDLSCs) are important seed cells in tissue engineering and clinical applications. They are the priority receptor cells for sensing various mechanical stresses.
Xuehuan Meng, Ye Zhu, Hao Tan, Baraa Daraqel, Ming Ye, Xiang Li, Guo-Yin Yang, Xinyi He, Jin-Lin Song, Lei-Lei Zheng   +9 more
semanticscholar   +1 more source

LIPUS Promotes Endothelial Differentiation and Angiogenesis of Periodontal Ligament Stem Cells by Activating Piezo1

International Journal of Stem Cells, 2022
Background and Objectives Low-intensity pulsed ultrasound (LIPUS) promotes differentiation and regulates biological functions of various stem cells, but its effect on the endothelial differentiation of periodontal ligament stem cells (PDLSCs) is unclear.
R. Hu, Zheng-Yan Yang, Yue-Heng Li, Zhi Zhou   +3 more
semanticscholar   +1 more source

Scopolamine regulates the osteogenic differentiation of human periodontal ligament stem cells through lactylation modification of RUNX2 protein

Pharmacology Research & Perspectives
Periodontal ligament stem cells (PDLSCs) are important mesenchymal stem cells contributing to regenerating lost periodontal tissues and repairing bone defects.
Yingdong Wu, Pan Gong
semanticscholar   +1 more source

Photobiomodulation effects on periodontal ligament stem cells: A systematic review of in-vitro studies.

Current Stem Cell Research & Therapy, 2022
BACKGROUND Stem cell therapy has been considered to play a paramount role in the treatment modalities available for regenerative dentistry. The established beneficial effects of photobiomodulation (PBM) at the cellular level have led to the combined use ...
Valina Mylona, E. Anagnostaki, N. Chiniforush, H. Barikani, E. Lynch, M. Grootveld   +5 more
semanticscholar   +1 more source

Domain of dentine sialoprotein mediates proliferation and differentiation of human periodontal ligament stem cells. [PDF]

PLoS ONE, 2013
Classic embryological studies have documented the inductive role of root dentin on adjacent periodontal ligament differentiation.  The biochemical composition of root dentin includes collagens and cleavage products of dentin sialophosphoprotein (DSPP ...
Alkan Ozer, Guohua Yuan, Guobin Yang, Feng Wang, Wentong Li, Yuan Yang, Feng Guo, Qingping Gao, Lisa Shoff, Zhi Chen, Isabel C Gay, Kevin J Donly, Mary MacDougall, Shuo Chen   +13 more
doaj   +1 more source

The role of PRX1-expressing cells in periodontal regeneration and wound healing

Frontiers in Physiology, 2023
The ideal outcome of wound healing is the complete restoration of the structure and function of the original tissue. Stem cells are one of the key factors in this process.
Zhen Huang, Xu Su, Miliya Julaiti, Xiaotao Chen, Qingxian Luan   +4 more
doaj   +1 more source