Results 61 to 70 of about 12,081 (284)

Stem cell-based tissue engineering for the regeneration of periodontal structures: A systemic review of current progress and barriers

open access: yesMedicine Science
Periodontal disease (PD) is characterized by gum inflammation, ranging from reversible gingivitis to irreversible periodontitis. Periodontitis compromises the foundation of oral health by degrading periodontal tissues that support teeth, namely the ...
Anahita Ghafarian, Sathees B Chandra
doaj   +1 more source

Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts

open access: yesPharmaceutics, 2022
Mesenchymal stem cells (MSC) are involved in the regeneration of various missing or compromised periodontal tissues, including bone. MSC-derived conditioned medium (CM) has recently been explored as a favorable surrogate for stem cell therapy, as it is ...
Solen Novello   +4 more
doaj   +1 more source

AI‐Driven Predictive Design and Functionalization of Three Dimensional‐Printed PEEK Implants with Tryptophan‐Enriched Alginate Hydrogel for Enhanced Biomimetic Surface Performance

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces an AI‐guided strategy to design 3D‐printed PEEK implants functionalized with a tryptophan‐enriched alginate hydrogel (TRYALPEEK). The modification improves hydrophilicity, reduces surface roughness, enhances cytocompatibility, and optimizes stress distribution. The platform offers a promising route for personalized implant design,
Wafa Benaatou   +8 more
wiley   +1 more source

Mesenchymal stem cell-mediated functional tooth regeneration in swine. [PDF]

open access: yesPLoS ONE, 2006
Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells ...
Wataru Sonoyama   +10 more
doaj   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Periodontal Ligament Stem Cells-The Regeneration Front [PDF]

open access: yesDentistry, 2015
The principal cells of the healthy, functional periodontal ligament are the differentiated cells and their progenitors. The differentiated cells are concerned with the synthesis and resorption of alveolar bone and the fibrous connective tissue of the ligament and cementum.
openaire   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

Advanced glycosylated end products restrain the osteogenic differentiation of the periodontal ligament stem cell

open access: yesJournal of Dental Sciences, 2019
Background/purpose: Many studies have confirmed that periodontal disease interacts with diabetes. The aim of this study was to examine whether the advanced glycosylated end products (AGEs), which are generated by diabetics, have important effects on the ...
Zhu-Ling Guo   +9 more
doaj   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

open access: yesBMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan   +7 more
wiley   +1 more source

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