Results 91 to 100 of about 2,424,442 (276)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Naloxone antagonizes the local antihyperalgesic effect of fentanyl in burnt skin of healthy humans [PDF]
, 2007 The aim of this study was to investigate local opioid effects in the inflamed skin of healthy human volunteers. To induce inflammation, the circular tip of a 10-mm-diameter probe was heated to 48°C and applied for 120 seconds to a site on each forearm of
Hammond, G.R. +2 more
core
EVALUATION OF EFFECTIVENESS OF HALOCYNTHIA AURANTIUM EXTRACT AT EXPERIMENTAL RAY IMPACT
В мире научных открытий, 2018 The effect of the extract from the marine hydrobiont Halocynthia aurantium (EA) under radiation exposure was studied. EA contains a complex of biologically active substances and has the ability to increase the nonspecific resistance of the organism to ...
Tatiana Ivanovna Ponomareva
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Accelerated peripheral dose calculation for radiotherapy
, 2021 La radiothérapie représente l'un des principaux traitements dont bénéficient les patients atteints par un cancer. Elle n'est toutefois pas sans risque~: les rayonnements ionisants utilisés pour détruire la tumeur peuvent favoriser l'apparition d'effets secondaires à long terme lorsqu'ils atteignent des régions éloignées de la zone traitée.
openaire +1 more source
Peripheral blood T Regulatory cell counts may not predict transplant rejection
BMC Immunology, 2010 Background Recent evidence shows that allograft survival rates show a positive correlation with the number of circulating T regulatory cells (Tregs). This study investigated both the number and the cytokine profiles exhibited by Foxp3+ Tregs in blood ...
Feng Li +6 more
doaj +1 more source
Evaluation of a new acrylic-lead shielding device for peripheral dose reduction during cone-beam computed tomography. [PDF]
BJR Open, 2022 Shimizu H +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source