Results 81 to 90 of about 1,737,462 (204)
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Peripheral blood T Regulatory cell counts may not predict transplant rejection
Background Recent evidence shows that allograft survival rates show a positive correlation with the number of circulating T regulatory cells (Tregs). This study investigated both the number and the cytokine profiles exhibited by Foxp3+ Tregs in blood ...
Feng Li +6 more
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Peripheral neuropathies of childhood [PDF]
Includes synopsis.Incldues bibliographical references (p. 195-220).Peripheral nerve disease was described by Galen (AD 130-200) over a thousand years ago.(3) Detailed anatomical illustrations were documented by Andreas Vesalius in his major work 'De ...
Wilmshurst, Jo
core +1 more source
CHROMOSOMAL ABERRATIONS AND MICRONUCLEI IN LYMPHOCYTES OF MEDICAL RADIATION WORKERS EXPOSED TO LONIZING RADIATION BELOW DOSE LIMIT [PDF]
Introduction: Ionizing radiation induces various kinds of DNA damage in which may lead to chromosomal aberrations (CA). Inspite of growing importance in the risk assessment, the dose yield kinetics of CA and their implications for dose assessment are not
MOZDARANI H, GOURABI H
doaj
Background: In radiation therapy, the peripheral dose is important when anatomical structures with very low dose tolerances are involved. In this study, the two available calculation algorithms of the Varian Eclipse 8.6 treatment planning system(TPS ...
Yavas, G., Yavas, C., Acar, H.
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Introduction High-energy LINAC X-rays are used instead of the traditional modality (γ-rays) in cancer radiotherapy. Health professionals may be exposed to these high-energy X-rays owing to mishandling or mechanical failure, and using a low-energy X-rays ...
Vishakh Radhakrishna +2 more
doaj +1 more source
Background This phase I trial was conducted to determine the safety and pharmacokinetics of monoclonal antibody 216, a human monoclonal Immunoglobulin M antibody targeting a linear B-cell lactosamine antigen, administered alone and in combination with ...
Michaela Liedtke +8 more
doaj +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source

