Results 31 to 40 of about 65,204 (262)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Peripheral Nerve Injury to the Lower Limb: Repair and Secondary Reconstruction

Indian Journal of Plastic Surgery, 2019
This article is based on literature review of relevant articles as well as the authors’ own experiences in treating peripheral nerve injuries of the lower limb.
Mukund R. Thatte, Amita Hiremath, Mayur S. Goklani, Neehar R. Patel, Anupam B. Takwale   +4 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Successful polyethylene glycol fusion repair using stored viable peripheral nerve allografts in Sprague–Dawley and Lewis rats

Neural Regeneration Research
We have previously shown the success of polyethylene glycol fusion repair of segmental-loss peripheral nerve injuries in rats using freshly harvested, viable peripheral nerve allografts that can conduct action potentials.
Liwen Zhou, Cathy Z. Yang, Alexander M. Schafer, Alexa N. Olivarez, Arjun Agarwal, Guhan Periyasamy, Karthik Venkudusamy, Yessenia Montoya, Varun Gokhale, Rhea Sood, Henry Garcia, Jared S. Bushman, George D. Bittner   +12 more
doaj   +1 more source

Traumatic injury to peripheral nerves

Muscle & Nerve, 2000
AbstractThis article reviews the epidemiology, classification, localization, prognosis, and mechanisms of recovery of traumatic peripheral nerve injuries (PNIs). Electrodiagnostic (EDx) assessments are critical components of treating patients with PNIs.
openaire   +6 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Micro-neurorrhaphy In peripheral Nerve injuries

Indian Journal of Plastic Surgery, 1991
Results of Repair under magnification, of 30 cases of peripheral nerve injuries of different nerves at different site, are presented. Success rate of the repair depends upon the meticulous care taken during surgery.
Prof. F.M. Tripathi, Dr. R.S. Kesari, Dr. A.K. Rai, Dr. U. Prakash, Prof. S. Mishra   +4 more
doaj   +1 more source

Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models

Bioactive Materials, 2023
Peripheral nerve injuries may result in severe long-gap interruptions that are challenging to repair. Autografting is the gold standard surgical approach for repairing long-gap nerve injuries but can result in prominent donor-site complications. Instead,
Xianhao Dong, Yueyue Yang, Zheheng Bao, Adam C. Midgley, Feiyi Li, Shuxin Dai, Zhuangzhuang Yang, Jin Wang, Lihua Liu, Wenlei Li, Yayuan Zheng, Siyang Liu, Yang Liu, Weijian Yu, Jun Liu, Meng Fan, Meifeng Zhu, Zhongyang Shen, Gu Xiaosong, Deling Kong   +19 more
doaj   +1 more source