Activity of Cyclic AMP Phosphodiesterases and Adenylyl Cyclase in Peripheral Nerve after Crush and Permanent Transection Injuries [PDF]
, 1998 Recent studies demonstrate that cAMP levels are tightly controlled during demyelination and remyelination in Schwann cells as cAMP decreases to 8–10% of normal following both sciatic nerve crush or permanent transection injury and only begins to increase
Poduslo, Joseph F. +1 more
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An examination of walking track analysis footprints of right-side unoperated limbs in rats prior to and following peripheral nerve injury and PEG fusion repair [PDF]
, 2018 Peripheral nerve injury can result in long-lasting functional deficits in humans due to mammals’ limited axon regenerative capacity. PEG fusion is a defined technique that fuses injured axons, resulting in morphological and electrophysiological ...
Jagannath, Karthik
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The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration
Frontiers in Bioengineering and Biotechnology, 2022 Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang +7 more
doaj +1 more source
Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. [PDF]
, 2020 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Basbaum, Allan I +8 more
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ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]
, 2004 Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Anderson, PN +6 more
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Trauma, 2003 Peripheral nerve injuries are common. Most are caused by lacerating or penetrating injuries. Failure to diagnose early leads to permanent disability. In the accident department absent two point discrimination or loss of sweating on the affected nger are clues to nerve injury.
A. A. Gehani, Atlantic D'Souza
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Tissue engineering for the repair of peripheral nerve injury
Neural Regeneration Research, 2019 Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering.
Pei-Xun Zhang +7 more
doaj +1 more source
Terminal complement activation is increased and associated with disease severity in CIDP [PDF]
, 2016 Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common chronic autoimmune neuropathy. While both cell-mediated and humoral mechanisms contribute to its pathogenesis, the rapid clinical response to plasmapheresis implicates a ...
Hiepe, Falk +4 more
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Effect of melatonin supplemented at the light or dark period on recovery of sciatic nerve injury in rats [PDF]
, 2017 Peripheral nerve injuries can cause disabilities, social or economic problems. Melatonin, the secretory product of the pineal gland has antioxidant and anti-inflammatory actions.
Amin, Shaimaa Nasr +4 more
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Peripheral Nerve Injury Induces Dynamic Changes of Tight Junction Components
Frontiers in Physiology, 2018 Tight junctions seal off physical barriers, regulate fluid and solute flow, and protect the endoneurial microenvironment of the peripheral nervous system. Physical barriers in the peripheral nervous system were disrupted after nerve injury.
Xinghui Wang +8 more
doaj +1 more source