Results 81 to 90 of about 1,895,537 (160)

2152

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: The goal of this pilot study is to provide a reliable anatomical algorithm for the measurement of adipose tissue within the pelvic cavity as a predictor of prostate cancer aggressiveness and recurrence after radical ...
Ana I. Ortiz, Juan C. Jorge, Lourdes Guerrios   +2 more
doaj   +1 more source

CRTC2 as a novel prognostic biomarker for worse pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with prostate cancer [PDF]

Investigative and Clinical Urology, 2019
Purpose: To identify the association between tumor metabolism and prostate cancer (PCa), we investigated the relationship between expression of metabolism-related genes and clinicopathologic outcomes in patients with localized PCa. Materials and Methods:
Hakmin Lee, Minseung Lee, Sung Kyu Hong
doaj   +1 more source

Pathology of a Canine Model of Localized Prostate Carcinoma

The Prostate, Volume 86, Issue 1, Page 65-83, January 2026.
ABSTRACT Background Dogs spontaneously develop prostate carcinoma (PC) and share prostate gland anatomy, physiology, and size to men. Over the last 15 years, we have developed and refined a canine model of focal PC to evaluate therapeutic‐diagnostic (theranostic) interventions.
Nathan K. Hoggard, Felipe M. Berg, Marlon R. Szczepaniak, Xinning Wang, Noriko Kantake, Gopalakrishnan Ramamurthy, Li Gong, Eric T. Hostnik, Krishan Kumar, Arijit Ghosh, Dong Luo, Michael V. Knopp, Jill M. Keller, Evan T. Keller, Agata A. Exner, James P. Basilion, Michael F. Tweedle, Thomas J. Rosol   +17 more
wiley   +1 more source

Periprostatic adipose tissue interacts with prostate cancer to promote aggressive disease

AME Medical Journal, 2018
Prostate cancer is now the most commonly diagnosed cancer among men in the developed world and is responsible for a significant number of cancer deaths each year (1). It has become increasingly clear that the epithelial component of the tumour itself is not the only aspect of the disease that determines clinical outcomes.
Ryan Stuchbery, Niall M. Corcoran
openaire   +1 more source

Signals from adipose tissue in morbid obesity and effect on depot specific differences [PDF]

, 2009
Signals from adipose tissue, such as interleukin-6 (IL-6) and asymmetric dimethyl arginine (ADMA), an endogenous nitric oxide inhibitor, explain the link between obesity and metabolic diseases.
Madani, R.
core  

Bigger challenges, similar outcomes: Robotic prostatectomy in the obese patient

BJUI Compass, Volume 6, Issue 11, November 2025.
Abstract Objectives The study aims to review the safety of performing robotic‐assisted radical prostatectomy (RARP) in patients with a body mass index (BMI) > 35 kg/m2 in a high‐volume robotic centre. Materials and methods A prospective database of all patients who underwent RARP between December 2015 and October 2024 was reviewed.
Andrew Evans, Ibrahim Ibrahim, Thomas Miller, Assia Djoudi, Katharine Hill, Imran Ahmad   +5 more
wiley   +1 more source

Extracellular Vesicles Released From Prostate Cancer Cells Confer Pro‐Tumor Properties to Adipocytes by Stimulating Lipolysis

BioFactors, Volume 51, Issue 6, November/December 2025.
Extracellular vesicles (EVs) from prostate cancer (PCa) cells induce the release of fatty acids (FFAs) from adipocytes, which in turn sustain tumor cell proliferation and migration via Akt activation. ABSTRACT There is consistent evidence of an association between obesity and the risk of prostate cancer (PCa). A crosstalk between PCa and adipocytes has
Gaia Giannitti, Kinga Kamińska, Sara Marchesi, Riccardo Garavaglia, Ivan Preosto, Małgorzata Grzesiak, Fabrizio Fontana   +6 more
wiley   +1 more source

Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

Journal of Hematology & Oncology, 2017
Background The causative role of the pro-inflammatory cytokine IL-6 in prostate cancer progression has been well established at molecular level. However, whether and how IL-6 may play a role in prostate cancer risk and development is not well defined ...
Gang Liu, Jinyu Zhang, Lewis Frey, Xiao Gang, Kongming Wu, Qian Liu, Michael Lilly, Jennifer Wu   +7 more
doaj   +1 more source

Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction

Molecular Nutrition &Food Research, Volume 69, Issue 10, May 2025.
Role of adipokines in the hypothalamic‐pituitary‐gonadal axis (HPG) during obesity. Obesity induces structural and functional changes in WAT, with a consequent imbalance in the production and secretion of adipokines. While the adipokines adiponectin and omentin‐1 are downregulated, the adipokines leptin, resistin, vifastin, apelin, and chemerin are ...
Fabiane Ferreira Martins, Maria do Socorro Medeiros Amarante, Daiana Santana Oliveira, Isabela Macedo Lopes Vasques‐Monteiro, Vanessa Souza‐Mello, Julio Beltrame Daleprane, Christina da Silva Camillo   +6 more
wiley   +1 more source

The Correlation Between Body Mass Index and Prostate Volume: A Retrospective Analysis of Pre and Postoperative Measurements in Prostate Cancer Patients

The Prostate, Volume 85, Issue 5, Page 433-442, April 2025.
ABSTRACT Background This study aims to assess the relationship between body mass index (BMI) and prostate volume, utilizing pre and postoperative measurements. Methods A retrospective, observational study was conducted at a single site using data from an institutional database.
Biagio Barone, Ugo Amicuzi, Matteo Massanova, Luigi Napolitano, Pasquale Reccia, Benito Fabio Mirto, Raffaele Balsamo, Francesco Del Giudice, Matteo Ferro, Gian Maria Busetto, Octavian Sabin Tataru, Giuseppe Lucarelli, Celeste Manfredi, Dario Del Biondo, Vincenzo Francesco Caputo, Roberto Falabella, Ferdinando Fusco, Ciro Imbimbo, Felice Crocetto   +18 more
wiley   +1 more source