Results 81 to 90 of about 1,069 (160)

An update of pitfalls in prostate mpMRI: a practical approach through the lens of PI-RADS v. 2 guidelines [PDF]

, 2018
ObJECTIVES: The aim of the current report is to provide an update in the imaging interpretation of prostate cancer on multiparametric magnetic resonance imaging (mpMRI), with a special focus on how to discriminate pathological tissue from the most common
Campa, R, Catalano, C, Ciardi, A, Cornud, F, De Rubeis, G, Giganti, F, Kitzing, YX, Panebianco, V, Villeirs, G   +8 more
core  

Adipoparacrinology: an Emerging Field in Biomedical Research

Balkan Medical Journal, 2012
White adipose tissue (WAT) is a dynamic multicellular assembly composed of adipocytes and stromovascular cells, including fibroblasts, endothelial and immune cells, nerve fibers, and stem cells. In humans, WAT is a responsive and secretory (endocrine and
George N. Chaldakov, Neşe Tunçel, Jerzy Beltowski, Marco Fiore, Gorana Ranćić, Anton Tonchev, Plamen Panayotov, Nikolai Evtimov, Alexander Hinev, Deyan Anakievski, Peter Ghenev, Luigi Aloe   +11 more
doaj  

Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

Journal of Hematology & Oncology, 2017
Background The causative role of the pro-inflammatory cytokine IL-6 in prostate cancer progression has been well established at molecular level. However, whether and how IL-6 may play a role in prostate cancer risk and development is not well defined ...
Gang Liu, Jinyu Zhang, Lewis Frey, Xiao Gang, Kongming Wu, Qian Liu, Michael Lilly, Jennifer Wu   +7 more
doaj   +1 more source

ピオグリタゾンによる肥満マウス前立腺周囲白色脂肪織の炎症抑制 [PDF]

, 2018
博士(医学) 乙第3001号(主論文の要旨、要約、審査結果の要旨)博士(医学 ...
宮澤 美季
core   +1 more source

Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction

Molecular Nutrition &Food Research, Volume 69, Issue 10, May 2025.
Role of adipokines in the hypothalamic‐pituitary‐gonadal axis (HPG) during obesity. Obesity induces structural and functional changes in WAT, with a consequent imbalance in the production and secretion of adipokines. While the adipokines adiponectin and omentin‐1 are downregulated, the adipokines leptin, resistin, vifastin, apelin, and chemerin are ...
Fabiane Ferreira Martins, Maria do Socorro Medeiros Amarante, Daiana Santana Oliveira, Isabela Macedo Lopes Vasques‐Monteiro, Vanessa Souza‐Mello, Julio Beltrame Daleprane, Christina da Silva Camillo   +6 more
wiley   +1 more source

Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress [PDF]

Molecular Cancer Research, 2019
Abstract Prostate gland is surrounded by periprostatic adipose tissue (PPAT), which is increasingly believed to play a paracrine role in prostate cancer progression. Our previous work demonstrates that adipocytes promote homing of prostate cancer cells to PPAT and that this effect is ...
Laurent, Victor, Toulet, Aurélie, Attané, Camille, Milhas, Delphine, Dauvillier, Stéphanie, Zaidi, Falek, Clement, Emily, Cinato, Mathieu, Le Gonidec, Sophie, Guérard, Adrien, Lehuédé, Camille, Garandeau, David, Nieto, Laurence, Renaud-Gabardos, Edith, Prats, Anne-Catherine, Valet, Philippe, Malavaud, Bernard, Muller, Catherine   +17 more
openaire   +2 more sources

The Correlation Between Body Mass Index and Prostate Volume: A Retrospective Analysis of Pre and Postoperative Measurements in Prostate Cancer Patients

The Prostate, Volume 85, Issue 5, Page 433-442, April 2025.
ABSTRACT Background This study aims to assess the relationship between body mass index (BMI) and prostate volume, utilizing pre and postoperative measurements. Methods A retrospective, observational study was conducted at a single site using data from an institutional database.
Biagio Barone, Ugo Amicuzi, Matteo Massanova, Luigi Napolitano, Pasquale Reccia, Benito Fabio Mirto, Raffaele Balsamo, Francesco Del Giudice, Matteo Ferro, Gian Maria Busetto, Octavian Sabin Tataru, Giuseppe Lucarelli, Celeste Manfredi, Dario Del Biondo, Vincenzo Francesco Caputo, Roberto Falabella, Ferdinando Fusco, Ciro Imbimbo, Felice Crocetto   +18 more
wiley   +1 more source

Development and Validation of an MRI‐Based Radiomics Nomogram to Predict the Prognosis of De Novo Oligometastatic Prostate Cancer Patients

Cancer Medicine, Volume 13, Issue 24, December 2024.
Illustration of radiomics study framework. We first extracted 1446 quantitative radiomic features from masked PCa T2‐weighted imaging and diffusion‐weighted imaging data. Next, univariate Cox regression analysis and the least absolute shrinkage and selection operator (LASSO) combined with 10‐fold cross‐validation were used to select the optimal ...
Wen‐Qi Liu, Yu‐Ting Xue, Xu‐Yun Huang, Bin Lin, Xiao‐Dong Li, Zhi‐Bin Ke, Dong‐Ning Chen, Jia‐Yin Chen, Yong Wei, Qing‐Shui Zheng, Xue‐Yi Xue, Ning Xu   +11 more
wiley   +1 more source

Lipids and adipocytes involvement in tumor progression with a focus on obesity and diet

Obesity Reviews, Volume 25, Issue 12, December 2024.
Summary The adipose tissue is a complex organ that can play endocrine, metabolic, and immune regulatory roles in cancer. In particular, adipocytes provide metabolic substrates for cancer cell proliferation and produce signaling molecules that can stimulate cell adhesion, migration, invasion, angiogenesis, and inflammation.
Chiara Calabrese, Giacomo Miserocchi, Alessandro De Vita, Chiara Spadazzi, Claudia Cocchi, Silvia Vanni, Sofia Gabellone, Giovanni Martinelli, Nicoletta Ranallo, Alberto Bongiovanni, Chiara Liverani   +10 more
wiley   +1 more source

Does the extent of extraprostatic extension at radical prostatectomy predict outcome?—a systematic review and meta‐analysis

Histopathology, Volume 85, Issue 5, Page 727-742, November 2024.
Extraprostatic extension (EPE) of prostate cancer is usually reported as either focal (F‐EPE) or established (E‐EPE), but data on the prognostic implication of this subdivision are conflicting. EPE alone is prognostic, but the value of subdivision by extent could not be demonstrated.
Lucia Lazzereschi, Jacqueline Birks, Richard Colling   +2 more
wiley   +1 more source