Results 71 to 80 of about 1,069 (160)

Periprostatic Adipose Tissue Mapping as a Diagnostic Predictor of Prostate Carcinoma

Journal of Radiology and Clinical Imaging, 2019
Periprostatic adipose tissue is a new topic being investigated to determine its utility in detecting and scoring prostate cancer. In the past, most of the studies related to prostate cancer relied on body mass index (BMI) to measure adiposity but showed conflicting results.
Shrestha Sukriti, Zhao Xinxiang
openaire   +1 more source

Use of parallel fluorescent confocal microscopy for detection of prostatic adenocarcinoma

BJU International, EarlyView.
Objective To provide a histological catalogue and defined criteria for the diagnosis of prostatic adenocarcinoma and its variants using the fluorescent confocal microscope (FCM) platform. Methods A total of 22 radical prostatectomy specimens were serially sectioned and scanned with the FCM.
Kevin Clare, Kenneth Haines, Jeremy Littlefield, Asher Mandel, Hannah Sur, Neeraja Tillu, Henry Jodka, Daniel Ajabshir, Fatima Ahmad, Chahat Arora, Cristina Pasat‐Karasik, Monali Fatterpekar, Ash Tewari, Ming Zhou   +13 more
wiley   +1 more source

CRTC2 as a novel prognostic biomarker for worse pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with prostate cancer [PDF]

Investigative and Clinical Urology, 2019
Purpose: To identify the association between tumor metabolism and prostate cancer (PCa), we investigated the relationship between expression of metabolism-related genes and clinicopathologic outcomes in patients with localized PCa. Materials and Methods:
Hakmin Lee, Minseung Lee, Sung Kyu Hong
doaj   +1 more source

Differentiated Pre-Adipocytes Act as a Driving Force For Prostate Cancer Proliferation, Migration and Epithelial-Mesenchymal Transition [PDF]

, 2022
Obesity is a popular topic due to both its mortality and morbidity rates and related diseases such as cardiovascular diseases, diabetes and cancer. Cancer development and progression relate to many factors one of which is dysfunctional adipocytes found
Abdik, Hüseyin, Erkılınçoğlu, Arya Lal, Şahin, Fikrettin   +2 more
core   +1 more source

Cancer Manipulates Adjacent Adipose Tissue to Exploit Fatty Acids via HIF‐1α/CCL2/PPARα Axis: A Metabolic Circuit to Support Tumor Progression

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Cancer cells drive adjacent adipose tissue to release fatty acids by secreting CCL2, which activates PPARα‐dependent lipolysis. The resulting fatty acid influx amplifies HIF‐1α/CCL2 signaling, establishing a positive feedback loop that fuels tumor growth.
Jeong‐Eun Yun, Jieun Seo, Jiwon Koh, Seock‐Ah Im, Ki Yong Hong, Yeseon Son, Do‐Won Jeong, Junji Fukuda, Jong‐Wan Park, Yang‐Sook Chun   +9 more
wiley   +1 more source

Periprostatic adipose tissue interacts with prostate cancer to promote aggressive disease

AME Medical Journal, 2018
Prostate cancer is now the most commonly diagnosed cancer among men in the developed world and is responsible for a significant number of cancer deaths each year (1). It has become increasingly clear that the epithelial component of the tumour itself is not the only aspect of the disease that determines clinical outcomes.
Ryan Stuchbery, Niall M. Corcoran
openaire   +1 more source

IMMUNOHISTOCHEMICAL EXPRESSION OF NGF/TrkA AND BDNF/TrkB IN TUMOR PARIENCHYMA AND PERIPROSTATIC ADIPOSE TISSUE, DEPENDING ON THE PATHOANATOMIC STAGE OF PROSTATE CANCER [PDF]

Journal of IMAB
Introduction: For more than 30 years, the idea of inhibiting growth factors has taken over the minds of different generations of scientists since the progression of the neoplastic process is determined by uncontrolled proliferation differentiation and ...
Nikolay Evtimov
doaj   +1 more source

Pathology of a Canine Model of Localized Prostate Carcinoma

The Prostate, Volume 86, Issue 1, Page 65-83, January 2026.
ABSTRACT Background Dogs spontaneously develop prostate carcinoma (PC) and share prostate gland anatomy, physiology, and size to men. Over the last 15 years, we have developed and refined a canine model of focal PC to evaluate therapeutic‐diagnostic (theranostic) interventions.
Nathan K. Hoggard, Felipe M. Berg, Marlon R. Szczepaniak, Xinning Wang, Noriko Kantake, Gopalakrishnan Ramamurthy, Li Gong, Eric T. Hostnik, Krishan Kumar, Arijit Ghosh, Dong Luo, Michael V. Knopp, Jill M. Keller, Evan T. Keller, Agata A. Exner, James P. Basilion, Michael F. Tweedle, Thomas J. Rosol   +17 more
wiley   +1 more source

2152

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: The goal of this pilot study is to provide a reliable anatomical algorithm for the measurement of adipose tissue within the pelvic cavity as a predictor of prostate cancer aggressiveness and recurrence after radical ...
Ana I. Ortiz, Juan C. Jorge, Lourdes Guerrios   +2 more
doaj   +1 more source

Bigger challenges, similar outcomes: Robotic prostatectomy in the obese patient

BJUI Compass, Volume 6, Issue 11, November 2025.
Abstract Objectives The study aims to review the safety of performing robotic‐assisted radical prostatectomy (RARP) in patients with a body mass index (BMI) > 35 kg/m2 in a high‐volume robotic centre. Materials and methods A prospective database of all patients who underwent RARP between December 2015 and October 2024 was reviewed.
Andrew Evans, Ibrahim Ibrahim, Thomas Miller, Assia Djoudi, Katharine Hill, Imran Ahmad   +5 more
wiley   +1 more source