Culturas primárias de tecido adiposo humano e impacto no cancro da próstata [PDF]
Mestrado em Biologia Aplicada - Molecular e CelularProstate cancer (Pca) is one of the most frequent diagnosed neoplasies and the second cause of cancer-related death in the world, in men. Between others risk factors, obesity has been associated to Pca
Cunha, Virgínia Filipa Pereira Monteiro da
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The defense of adipose tissue against excess substrate-induced hyperthrophia: Immune system cell infiltration and arrested metabolic activity [PDF]
Obesity, the excessive accumulation of body fat, is a main defining feature of the metabolic syndrome, and overweight is often an early indication of the future severity and development of associated pathologies.
Alemany, Marià, 1946-, Marià Alemany
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Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
ABSTRACT Obesity is increasingly recognised as an important factor contributing to cancer progression, particularly in breast cancer. However, the cellular and molecular mechanisms underlying obesity‐driven breast cancer remain unclear. Several theories have been proposed to explain the complex interactions between adipose tissue and cancer ...
Charlise Basson +3 more
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The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network. [PDF]
Elevated circulating cholesterol is a systemic risk factor for cardiovascular disease and metabolic syndrome, however the manner in which the normal prostate responds to variations in cholesterol levels is poorly understood.
Jayoung Kim +10 more
doaj +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
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The anti-angiogenic herbal composition Ob-X inhibits adipose tissue growth in obese mice [PDF]
Objective: The growth and development of adipose tissue are thought to be associated with angiogenesis and extracellular matrix remodeling. Since the composition of the herbal extract called Ob-X has been shown to have both anti-angiogenic and matrix ...
Min-Young Kim +9 more
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Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
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Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways
ABSTRACT Obesity is a global health crisis affecting millions, associated with metabolic disorders such as type 2 diabetes and cardiovascular disease. Calebin‐A, a bioactive compound derived from Curcuma species, has shown promise in managing obesity and its complications.
Ali Mahmoudi +4 more
wiley +1 more source
Cancer Science, Volume 117, Issue S1, Page 1-2148, January 2026.
wiley +3 more sources

