Results 61 to 70 of about 1,069 (160)

Dietary restriction: could it be considered as speed bump on tumor progression road? [PDF]

, 2016
Dietary restrictions, including fasting (or long-term starvation), calorie restriction (CR), and short-term starvation (STS), are considered a strong rationale that may protect against various diseases, including age-related diseases and cancer.
Barraco, Nadia, BAZAN, Viviana, BRONTE, Giuseppe, Cangemi, Antonina, CASTIGLIA, Marta, FANALE, Daniele, GALVANO, Antonio, Massihnia, Daniela, MIRISOLA, Mario Giuseppe, Perez, Alessandro, Rinaldi, G., RUSSO, Antonio, VIENI, Salvatore   +12 more
core   +1 more source

Tumor Cell-educated Periprostatic Adipose Tissue Acquires an Aggressive Cancer-promoting Secretory Profile [PDF]

Cellular Physiology and Biochemistry, 2012
The microenvironment produces important factors that are crucial to prostate cancer (PCa) progression. However, the extent to which the cancer cells stimulate periprostatic adipose tissue (PPAT) to produce these proteins is largely unknown. Our purpose was to determine whether PCa cell-derived factors influence PPAT metabolic activity.Primary cultures ...
Ricardo J T, Ribeiro, Cátia P D, Monteiro, Virginia F P M, Cunha, Andreia S M, Azevedo, Maria J, Oliveira, Rosário, Monteiro, Avelino M, Fraga, Paulo, Príncipe, Carlos, Lobato, Francisco, Lobo, António, Morais, Vitor, Silva, José, Sanches-Magalhães, Jorge, Oliveira, João T, Guimarães, Carlos M S, Lopes, Rui M, Medeiros   +16 more
openaire   +2 more sources

Role of Lipids and Lipid Metabolism in Prostate Cancer Progression and the Tumor’s Immune Environment [PDF]

, 2022
Modulation of lipid metabolism during cancer development and progression is one of the hallmarks of cancer in solid tumors; its importance in prostate cancer (PCa) has been demonstrated in numerous studies.
Gao, Yuan, Lou, Yan-Ru, Murtola, Teemu J., Siltari, Aino, Syvälä, Heimo   +4 more
core   +3 more sources

Effects of Dietary Restriction on Cancer Development and Progression [PDF]

, 2017
The effects of caloric restriction on tumor growth and progression are known for over a century. Indeed, fasting has been practiced for millennia, but just recently has emerged the protective role that it may exert toward cells.
A Cangemi, A Russo, AG Renehan, AJ Dirks-Naylor, B Dirat, BM Reid, C Lee, C Lee, C Lee, C Lu, CE Champ, D Fanale, D Fanale, D Hanahan, D Massihnia, E Cadoni, E Giovannucci, E Laconi, EE Calle, F Madia, F Passiglia, F Premoselli, FM Safdie, G Flemstrom, GL Lluch, H Remmen Van, H Yamaza, HH Hermsdorff, HY Cohen, J Jin, J Standard, JF Trepanowski, K Esposito, KL Tinkum, L Fontana, L Hlavata, L Paglia La, L Raffaghello, L Siggens, L Xie, LK Heilbronn, LM Berstein, LT Robertson, M Lefevre, M Lv, M Prisco, MM Ramsey, MP Cleary, NY Kalaany, P Toren, R Ribeiro, RJ Klement, S Anton, S Brandhorst, S Pirkmajer, T Chiba, T Duan, TN Seyfried, VD Longo, VD Longo, VD Longo, Y Katsuya, Y Shi, YY Wang, Z Al-Wahab   +64 more
core   +1 more source

The Adipose Mast Cell: Mastokines As Binary Modulators Of Disease Processes [PDF]

, 2021
A paradigm-shifting discovery of the hormone leptin (in the end of 1994) paved the way toward intensive studies on endocrine and paracrine function of the adipose tissue.
Evtimov, Nikolai T., Pancheva, Rouzha Z., Ranćić, Gorana, Tunçel, Neşe   +3 more
core   +2 more sources

Ex vivo fluorescence confocal microscopy: prostatic and periprostatic tissues atlas and evaluation of the learning curve [PDF]

, 2020
Ex vivo fluorescence confocal microscopy (FCM) is an optical technology that provides fast H&E-like images of freshly excised tissues, and it has been mainly used for “real-time” pathological examination of dermatological malignancies.
Azzoni P., Bertoni L., Bevilacqua L., Bianchi G., Eissa A., Kaleci S., Maiorana A., Micali S., Montironi R., Pellacani G., Puliatti S., Reggiani Bonetti L., Rocco B., Sighinolfi M. C., Spandri V., Zoeir A.   +15 more
core   +1 more source

The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network. [PDF]

PLoS ONE, 2012
Elevated circulating cholesterol is a systemic risk factor for cardiovascular disease and metabolic syndrome, however the manner in which the normal prostate responds to variations in cholesterol levels is poorly understood.
Jayoung Kim, Dolores Di Vizio, Taek-Kyun Kim, Jonghwan Kim, Minjung Kim, Kristine Pelton, Steven K Clinton, Tsonwin Hai, Daehee Hwang, Keith R Solomon, Michael R Freeman   +10 more
doaj   +1 more source

Development of a High-Performance Thin-Layer Chromatography Method for the Quantification of Alkyl Glycerolipids and Alkenyl Glycerolipids from Shark and Chimera Oils and Tissues

Marine Drugs, 2022
Ether lipids are composed of alkyl lipids with an ether bond at the sn-1 position of a glycerol backbone and alkenyl lipids, which possess a vinyl ether bond at the sn-1 position of the glycerol.
Marion Papin, Cyrille Guimaraes, Benoit Pierre-Aue, Delphine Fontaine, Jeoffrey Pardessus, Hélène Couthon, Gaëlle Fromont, Karine Mahéo, Aurélie Chantôme, Christophe Vandier, Michelle Pinault   +10 more
doaj   +1 more source

Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer [PDF]

, 2017
Background In this study we sought if, in their quest to handle hypoxia, prostate tumors express target hypoxia-associated molecules and their correlation with putative functional genetic polymorphisms.
Coelho, A., Coutinho, H., Fraga, A., Lobato, C., Lopes, C., Lopes, J., Medeiros, R., Príncipe, P., Ribeiro, R., Vizcaíno, J.   +9 more
core   +4 more sources

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source