Results 41 to 50 of about 1,069 (160)

Pioglitazone Inhibits Periprostatic White Adipose Tissue Inflammation in Obese Mice [PDF]

Cancer Prevention Research, 2018
AbstractObesity is associated with an increased incidence of high-grade prostate cancer and poor prognosis for prostate cancer patients. Recently, we showed that obesity-related periprostatic white adipose tissue (WAT) inflammation, characterized by crown-like structures (CLS) consisting of dead or dying adipocytes surrounded by macrophages, was ...
Miki, Miyazawa, Kotha, Subbaramaiah, Priya, Bhardwaj, Xi Kathy, Zhou, Hanhan, Wang, Domenick J, Falcone, Dilip D, Giri, Andrew J, Dannenberg   +7 more
openaire   +2 more sources

Periprostatic Adipose Tissue Displays a Chronic Hypoxic State that Limits Its Expandability

The American Journal of Pathology, 2022
White adipose tissue accumulates at various sites throughout the body, some adipose tissue depots exist near organs whose function they influence in a paracrine manner. Prostate gland is surrounded by a poorly characterized adipose depot called periprostatic adipose tissue (PPAT), which plays emerging roles in prostate-related disorders.
Roumiguié, Mathieu, Estève, David, Manceau, Cécile, Toulet, Aurélie, Gilleron, Jérôme, Belles, Chloé, Jia, Yiyue, Houël, Cynthia, Pericart, Sarah, Legonidec, Sophie, Valet, Philippe, Cormont, Mireille, Tanti, Jean‐françois, Malavaud, Bernard, Bouloumié, Anne, Milhas, Delphine, Muller, Catherine   +16 more
openaire   +2 more sources

Does prostate acinar adenocarcinoma with Gleason Score 3 + 3 = 6 have the potential to metastasize? [PDF]

, 2014
Background: There is a worldwide debate involving clinicians, uropathologists as well as patients and their families on whether Gleason score 6 adenocarcinoma should be labelled as cancer.
Briganti, Alberto, Cheng, Liang, Lopez-Beltran, Antonio, Mazzucchelli, Roberta, Montironi, Rodolfo, Montorsi, Francesco, Santoni, Matteo, Scarpelli, Marina   +7 more
core   +3 more sources

Prognostic Value of CT-Attenuation and ¹⁸F-Fluorodeoxyglucose Uptake of Periprostatic Adipose Tissue in Patients with Prostate Cancer. [PDF]

J Pers Med, 2020
This study aimed to assess the prognostic value of computed tomography (CT)-attenuation and 18F-fluorodeoxyglucose (FDG) uptake of periprostatic adipose tissue (PPAT) for predicting disease progression-free survival (DPFS) in patients with prostate cancer.
Lee JW, Jeon YS, Kim KH, Yang HJ, Lee CH, Lee SM.   +5 more
europepmc   +4 more sources

MRI-measured adipose features as predictive factors for detection of prostate cancer in males undergoing systematic prostate biopsy: a retrospective study based on a Chinese population

Adipocyte, 2022
In this study, we retrospectively evaluated the data of 901 men undergoing ultrasonography-guided systematic prostate biopsy between March 2013 and May 2022.
Tianyu Xiong, Fang Cao, Guangyi Zhu, Xiaobo Ye, Yun Cui, Huibo Zhang, Yinong Niu   +6 more
doaj   +1 more source

Periprostatic Fat Adipokines Expression Correlated with Prostate Cancer Aggressiveness in Men Undergoing Radical Prostatectomy for Clinically Localised Disease [PDF]

, 2019
Objectives: To investigate relationship between periprostatic adipose tissue (PPAT) adipokines expression and PCa aggressiveness using both pathological features of radical prostatectomy (RP) and multiparametric MRI parameters.Patients and Methods: Sixty-
Alberti, Bastard, Bastard, Bhindi, Cao, Cawthorn, Chadha, Claffey, Cousin, Dahran, Grivennikov, Gucalp, Heilbronn, Hube, Ibrahim, Ito, Kalkanis, Khandekar, Laurent, Lee, Liu, Muller, Nieman, Olefsky, Ouchi, Paz-Filho, Powell, Prins, Ribeiro, Ribeiro, Roermund, Roermund, Roskoski, Roskoski, Rutkowski, Rydén, Saito, Sasaki, Sethi, Szlosarek, Takano, Tan, Viglietto, Waki, Wang, Wei, Weisberg, Wellen, Woo, Xu, Zhang, Zhang, Zhang   +52 more
core   +2 more sources

Normalized periprostatic fat MRI measurements can predict prostate cancer aggressiveness in men undergoing radical prostatectomy for clinically localised disease [PDF]

, 2017
Periprostatic and pelvic fat have been shown to influence prostate cancer behaviour through the secretion of chemokines and growth factors, acting in a paracrine mode.
B Bhindi, C Muller, C Rodriguez, CE Paaskesen, CL Amling, CL Ogden, CS Hung, D Palma, D Shungin, DS Finley, IJ Powell, JG Roermund Van, JG Roermund Van, JG Roermund Van, JM Rutkowski, K Harada, K Ohwaki, K Powell, K Rennie, K Saglam, KM Nieman., L Keaver, M Shields, MS Cohen, N Ouchi, P Hafe Von, Q Zhang, R Ribeiro, RA Taylor, S Woo, SJ Freedland, V Laurent, Y Liu, YY Wang   +33 more
core   +2 more sources

Influence of body mass index and periprostatic fat on rectal dosimetry in permanent seed prostate brachytherapy [PDF]

, 2014
PURPOSE: We examined the influence of body mass index (BMI) and body fat distribution on rectal dose in patients treated with permanent seed brachytherapy for localized prostate cancer.
Aliza Meissner, Daniel Taussky, David Tiberi, Guila Delouya, Nelson Gruszczynski   +4 more
core   +2 more sources

The relationship of obesity and prostate cancer (review)

Ожирение и метаболизм, 2020
Obesity is a critical risk factor for prostate cancer (PCa). Adipose tissue plays an important role in tumor development, including growth, invasion, and metastasis.
Maxim N. Peshkov, Galina P. Peshkova, Igor V. Reshetov   +2 more
doaj   +1 more source

Peri-prostatic fat volume measurement as a predictive tool for castration resistance in advanced prostate cancer [PDF]

, 2018
Background: Obesity and aggressive prostate cancer (PC) may be linked, but how local peri-prostatic fat relates to tumour response following androgen deprivation therapy (ADT) is unknown.
Ahmad, Imran, Hendry, Jane, Leung, Hing Y., Nixon, Colin, Patel, Amit, Salji, Mark   +5 more
core   +1 more source