Results 21 to 30 of about 1,069 (160)

Changes in periprostatic adipose tissue induced by 5α‐reductase inhibitors [PDF]

Andrology, 2017
SummaryThere is increasing interest in periprostatic fat and its influence on prostate cancer aggressiveness. In vitro data suggest that adipose stromal/stem cells (ASCs) can increase production of cytokines and growth factors resulting in invasive growth and metastasis in prostate cancer.
D, Taussky, M, Barkati, S, Campeau, K, Zerouali, A, Nadiri, F, Saad, G, Delouya   +6 more
openaire   +4 more sources

Tumoral periprostatic adipose tissue exovesicles-derived miR-20a-5p regulates prostate cancer cell proliferation and inflammation through the RORA gene [PDF]

Journal of Translational Medicine
Background From the first steps of prostate cancer (PCa) initiation, tumours are in contact with the most-proximal adipose tissue called periprostatic adipose tissue (PPAT).
Silvia Sánchez-Martin, Antonio Altuna-Coy, Verónica Arreaza-Gil, Xana Bernal-Escoté, Joan Francesc Garcia Fontgivell, Helena Ascaso-Til, José Segarra-Tomás, Xavier Ruiz-Plazas, Matilde R. Chacón   +8 more
doaj   +2 more sources

Adipoparacrinology: periprostatic adipose tissue as an example [PDF]

Adipobiology, 2011
The global epidemic of obesity (globesity) and related cardiometabolic and cancer diseases has focused attention on adipose tissue biology and the role played by adipose-secreted bioactive molecules (adipokines, neurotrophic factors, fatty acids ...
Anakievski, Deyan, Chaldakov, George N., Evtimov, Nikolai, Ghenev, Peter I., Hinev, Alexandar I., Zhelezov, Marin   +5 more
core   +3 more sources

Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel [PDF]

Medical Sciences
Background: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors increase PCa aggressiveness and ...
Mariana Feijó, Lara R. S. Fonseca, Gonçalo Catarro, Cátia V. Vaz, Carlos Rabaça, Bruno J. Pereira, Eugenia Gallardo, Endre Kiss-Toth, Sara Correia, Sílvia Socorro   +9 more
doaj   +2 more sources

A novel composite index of PSA and periprostatic adipose tissue quantification for enhancing high-grade prostate cancer prediction [PDF]

BMC Urology
Background To explore the efficacy of combining MRI-derived quantitative data on Periprostatic adipose tissue (PPAT) with clinical biomarkers, including prostate-specific antigen (PSA), to enhance the high-grade (PCa) screening.
Jie Xiong, Yunfan Liu, Xiaofeng Qiao, Guangyong Ai, Jiangqin Ma, Xiaojing He   +5 more
doaj   +2 more sources

Periprostatic adipose tissue-derived extracellular vesicles modulate prostate cancer cell behaviour in vitro according to tumour grade [PDF]

Molecular Medicine
Background Periprostatic adipose tissue (PPAT) actively interacts with prostate cancer (PCa) cells, partly through the release of extracellular vesicles (EVs).
Verónica Arreaza-Gil, Gabriela A. Altamirano, Antonio Altuna-Coy, Alazne Moreno-Lanceta, Silvia Sánchez-Martin, Natalia Diaz-Valdivia, Jordi Alcaraz, Xana Bernal- Escoté, Joan Francesc Garcia-Fontgivell, Helena Ascaso-Til, José Segarra-Tomás, Xavier Ruiz-Plazas, Matilde R. Chacón   +12 more
doaj   +2 more sources

Radiologic Assessment of Periprostatic Fat as an Indicator of Prostate Cancer Risk on Multiparametric MRI [PDF]

Bioengineering
Prostate cancer remains one of the most prevalent malignancies among men, and emerging evidence proposed a potential role for periprostatic adipose tissue (PPAT) in tumor progression.
Roxana Iacob, Emil Radu Iacob, Emil Robert Stoicescu, Diana Manolescu, Laura Andreea Ghenciu, Radu Căprariu, Amalia Constantinescu, Iulia Ciobanu, Răzvan Bardan, Alin Cumpănaș   +9 more
doaj   +2 more sources

Assessment of Periprostatic and Subcutaneous Adipose Tissue Lipolysis and Adipocyte Size from Men with Localized Prostate Cancer [PDF]

Cancers, 2020
The prostate is surrounded by periprostatic adipose tissue (PPAT), the thickness of which has been associated with more aggressive prostate cancer (PCa). There are limited data regarding the functional characteristics of PPAT, how it compares to subcutaneous adipose tissue (SAT), and whether in a setting of localized PCa, these traits are altered by ...
Dushan Miladinovic, Thomas Cusick, Kate L. Mahon, Anne-Maree Haynes, Colin H. Cortie, Barbara J. Meyer, Phillip D. Stricker, Gary A. Wittert, Lisa M. Butler, Lisa G. Horvath, Andrew J. Hoy   +10 more
openaire   +5 more sources

Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection. [PDF]

Immun Inflamm Dis
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Duan X, Li R, Fu L, Yang J, Zhan Z.
europepmc   +2 more sources

MRI-measured periprostatic to subcutaneous adipose tissue thickness ratio as an independent risk factor in prostate cancer patients undergoing radical prostatectomy [PDF]

Scientific Reports
The purpose of this study is to evaluate whether the periprostatic adipose tissue thickness (PPATT) is an independent prognostic factor for prostate cancer patients after laparoscopic radical prostatectomy (LRP).
Shanshan Jiang, Yi Li, Yusheng Guo, Bingxin Gong, Chengcheng Wei, Weiwei Liu, Chao Chen, Feng Pan, Jiyu Song, Qingliu He, Lian Yang, Guofeng Zhou   +11 more
doaj   +2 more sources