Results 91 to 100 of about 288,150 (296)

Role of aggressive surgery for peritoneal metastases

European Journal of Cancer Supplements, 2013
1359-6349/$ see front matter Copyright 2013 ECCO the European CanCer Organisation. All rights reserved. http://dx.doi.org/10.1016/j.ejcsup.2013.07.036 * Corresponding author: Address: Gustave Roussy, 114 Rue Edouard Vaillant, 94807 Villejuif, France. Tel.: +33 1 42 11 40 85. E-mail address: dominique.elias@gustaveroussy.fr (D. Elias). Dominique Elias *,
Elias, Dominique, Dumont, Frédéric, Honoré, Charles, Goéré, Diane   +3 more
openaire   +2 more sources

Gastric cancer: prevention and treatment of peritoneal metastases

, 2018
Gastric cancer is an aggressive malignancy that may metastasize through the bloodstream to the liver, through lymphatics to regional lymph nodes, or by penetration of the peritoneal lining of the stomach to result in seeding of the abdominal and pelvis ...
Sugarbaker, Paul H.
core  

Survival Results by the Prospectively Determined Clinical Staging for Locally Advanced Gastric Cancer: A Follow‐Up Study of JCOG1302A

Annals of Gastroenterological Surgery, EarlyView.
Prospectively determined clinical T and N categories clearly stratified long‐term survival in locally advanced gastric cancer. Patients with cT3N+, cT4aN0, cT4aN+, and cT4b disease showed unfavorable prognosis despite standard treatment. These findings may help optimize patient selection for perioperative treatment strategies.
Tsutomu Hayashi, Ryosuke Kato, Noriko Mitome, Rei Ogawa, Takeo Fukagawa, Hitoshi Katai, Souya Nunobe, Masanori Tokunaga, Etsuro Bando, Yuichi Ito, Takanobu Yamada, Takashi Nomura, Shigeto Makino, Takahiro Kinoshita, Hisashi Hara, Masaki Aizawa, Narikazu Boku, Yukinori Kurokawa, Masanori Terashima, Takaki Yoshikawa   +19 more
wiley   +1 more source

Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment in patients with advanced gastric or gastroesophageal junction adenocarcinoma, with or without peritoneal metastases: a post-hoc analysis on RATIONALE-305 studyResearch in context

EClinicalMedicine
Summary: Background: While immunotherapy plus chemotherapy is the current first-line standard for gastric or gastroesophageal junction adenocarcinoma (GC/GEJC), subgroup analyses in patients with peritoneal metastasis are limited and show inconsistent ...
Miao-Zhen Qiu, Keun-Wook Lee, Markus Möhler, Hui-Yan Luo, Hidekazu Hirano, Tao Zhang, Feng-Hua Wang, Yi Ba, Sun Young Rha, Feng Wang, Ming-Ming He, Sheng Xu, Xiaoxi Pan, Rui-Hua Xu   +13 more
doaj   +1 more source

Metastasis Pattern‐Specific Biomarkers and Therapeutic Targets in Gastric Cancer: From Surgical Specimens to Clinical Translation

Annals of Gastroenterological Surgery, EarlyView.
Gastric cancer metastasis should be considered according to its anatomical route, because lymphatic, peritoneal, and hematogenous dissemination involve partly distinct molecular mechanisms. This review summarizes metastasis pattern‐associated and pattern‐specific molecules identified using surgical specimens, evaluates their evidence and translational ...
Mitsuro Kanda
wiley   +1 more source

Prolonged Survival in a Patient with Neuroendocrine Tumor of the Cecum and Diffuse Peritoneal Carcinomatosis

Case Reports in Gastroenterology, 2012
Peritoneal carcinomatosis is a well-known factor of poor prognosis in patients with digestive adenocarcinomas. Peritoneal dissemination may also occur in midgut well-differentiated neuroendocrine tumors, but its influence on survival is ill-defined.
Louis de Mestier, Cindy Neuzillet, Olivia Hentic, Reza Kianmanesh, Pascal Hammel, Philippe Ruszniewski   +5 more
doaj   +1 more source

Refining OVCAR‐3 xenograft models of peritoneal carcinomatosis in nu/nu mice: Comparative intraperitoneal implantation strategies and the role of basement membrane matrix

Animal Models and Experimental Medicine, EarlyView.
A refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
M. Teresa Perelló‐Trias, Antonio Jose Serrano‐Muñoz, Juan J. Segura‐Sampedro, Adriana M. Quintero‐Duarte, Joana M. Ramis, Marta Monjo   +5 more
wiley   +1 more source

Overall (OS) and disease-free survival (DFS) after complete cytoreductive surgery in patients with DSRCT without extra-peritoneal metastases.

, 2017
Overall (OS) and disease-free survival (DFS) after complete cytoreductive surgery in patients with DSRCT without extra-peritoneal metastases.
A. LeCesne (3778477), J. B. Delhorme (3778444), O. Glehen (3778474), D. Orbach (3778465), S. Bonvalot (3778453), P. Terrier (3778456), D. Elias (3778480), O. Mir (3778468), S. Msika (3778462), S. Sarnacki (3778438), H. Martelli (3778447), C. Honoré (3778450), V. Atallah (3778429), P. Philippe-Chomette (3778483), V. Minard-Colin (3778471), J. Y. Blay (3778435), P. Sargos (3778432), G. Ferron (3778459), F. Bertucci (3524012), C. LePéchoux (3778441)   +19 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Assessment of surgical resectability of pancreatic adenocarcinomas with multidetector computed tomography: What are the possibilities and problems?

The Turkish Journal of Gastroenterology, 2014
Background/Aims: To investigate the accuracy of multidetector computed tomography (MDCT) in preoperatively determining the surgical resectability of pancreatic adenocarcinomas.
Esra İşcanlı, Aysel Türkvatan, Erdal Birol Bostancı, Zişan Sakaoğulları   +3 more
doaj   +1 more source