Results 161 to 170 of about 821,529 (204)

Immune Reprogramming Precision Photodynamic Therapy of Peritoneal Metastasis by Scalable Stem-Cell-Derived Extracellular Vesicles.

ACS Nano, 2021
The dissemination of tumor metastasis in the peritoneal cavity, also called peritoneal metastasis (PM) or carcinomatosis, represents a late stage of gastrointestinal and gynecological cancer with very poor prognosis, even when cytoreductive surgery is ...
A. Pinto, Iris Marangon, J. Méreaux, A. Nicolás-Boluda, Grégory Lavieu, C. Wilhelm, Laure Sarda-Mantel, A. Silva, M. Pocard, F. Gazeau   +9 more
semanticscholar   +1 more source

PIPAC for Advanced Peritoneal Metastasis

2021
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel and advanced tool for the treatment of peritoneal metastasis. Due in part to the invasiveness of CRS/HIPEC and the often aggressive biology or advanced stage of peritoneal metastasis, it has become increasingly recognized that the risks of any intervention need to be carefully weighed ...
Kuno Lehmann, Wiebke Solass, Lilian Roth, Joshua R. Kapp, Clemens B. Tempfer, Marc A. Reymond   +5 more
openaire   +1 more source

Tumor-Selective Immune-Active Mild Hyperthermia Associated with Chemotherapy in Colon Peritoneal Metastasis by Photoactivation of Fluorouracil-Gold Nanoparticle Complexes.

ACS Nano, 2021
Peritoneal metastasis (PM) is considered as the terminal stage of metastatic colon cancer, with still poor median survival rate even with the best recent chemotherapy treatment.
Vladimir Mulens-Arias, A. Nicolás-Boluda, A. Pinto, Alice Balfourier, F. Carn, A. Silva, M. Pocard, F. Gazeau   +7 more
semanticscholar   +1 more source

Mechanisms of Peritoneal Metastasis Formation

2020
Mechanisms of peritoneal metastasis (PM) formation remain unclear. It has long been considered that the establishment of PM is a multi-step process. Here are the recent new concepts of the formation of PM, in terms of three patterns of PM: trans-mesothelial, trans-lymphatic, and superficial growing metastasis.
Yutaka Yonemura, Haruaki Ishibashi, Akiyoshi Mizumoto, Kazuo Nishihara, Yang Liu, Satoshi Wakama, Syouzou Sako, Nobuyuki Takao, Masumi Ichinose, Shun-ichi Motoi, Keizou Taniguchi, Sachio Fushida, Yoshio Endou, Masahiro Miura   +13 more
openaire   +1 more source

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Journal of Visualized Experiments, 2016
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic malignancy in the United States. Mortality is due to diagnosis of 75% of women with late stage disease, when metastasis is already present. EOC is characterized by diffuse and widely disseminated intra-peritoneal metastasis.
Kyle A, Lewellen, Matthew N, Metzinger, Yueying, Liu, M Sharon, Stack   +3 more
openaire   +2 more sources

Peritoneal Tumour DNA in Peritoneal Fluid: Emerging Tool for Peritoneal Metastasis Detection

Journal of Gastrointestinal Cancer
The prognostic significance of positive peritoneal cytology still varied between cancer types and geographical origin. However, because of the lack of sensitivity of this biomarker, conventional cytology is not routinely performed in every country. Here, we wanted to test a new biomarker, peritoneal tumour DNA, using NGS technique, in order to compare ...
Antoine, Mariani, Hélène, Blons, Henri, Azais, Pierre, Laurent-Puig, Aziz, Zaanan, Amira, Gharbi   +5 more
openaire   +2 more sources

Peritoneal Metastasis of Retroperitoneal Tumors

2017
Introduction Peritoneal metastases of retroperitoneal tumors are in general rare. They can arise as synchronous peritoneal seeding of the primary tumor or as a tumor recurrence after surgery affecting the peritoneum. This review illustrates the different retroperitoneal tumor etiologies which can present peritoneal surface malignancies and is ...
Andreas Brandl, Christina Barbara Schäfer, Beate Rau   +2 more
openaire   +1 more source

Peritoneal high-fat environment promotes peritoneal metastasis of gastric cancer cells through activation of NSUN2-mediated ORAI2 m5C modification

Oncogene, 2023
Kanghui Liu, P. Xu, Jialun Lv, H. Ge, Zhengyuan Yan, Shansong Huang, Bowen Li, Hao Xu, Li Yang, Zekuan Xu, Diancai Zhang   +10 more
semanticscholar   +1 more source

Rationale of Treatment for Peritoneal Metastasis.

Gan to kagaku ryoho. Cancer & chemotherapy, 2023
In 1998, the Peritoneal Surface Oncology Group International(PSOGI)proposed a novel treatment referred to as comprehensive treatment(COMPT). COMPT involves the complete removal of macroscopic tumors(cytoreductive surgery: CRS) and eradication of micrometastasis(MM)with neoadjuvant chemotherapy(NAC)plus intraoperative hyperthermic intraperitoneal ...
Yutaka, Yonemura, Haruaki, Ishibashi, Akiyoshi, Mizumoto, Takuji, Fujita, Yang, Liu, Satoshi, Wakama, Syouzou, Sako, Nobuyuki, Takao, Toshiyuki, Kitai, Kanji, Katayama, Yasuyuki, Kamada, Keizou, Taniguchi, Daisuke, Fujimoto   +12 more
openaire   +1 more source

Nanomotor-driven precision therapy for peritoneal metastasis

Biomaterials
Peritoneal metastasis (PM) is a terminal stage of gastrointestinal cancers, often resulting in poor survival outcomes. Traditional treatments like cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have shown some effectiveness but are associated with significant risks.
Yaoguang She, Jianxin Cui, Jiamin Ye, Fei Pan, Wenquan Liang, Xiaofeng He, Di Wu, Xiaoyuan Ji, Chunxi Wang   +8 more
openaire   +2 more sources