Results 51 to 60 of about 821,529 (204)

Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer

International Journal of Molecular Sciences, 2021
Most patients with ovarian cancer (OvCA) present peritoneal disseminated disease at the time of diagnosis. During peritoneal metastasis, cancer cells detach from the primary tumor and disseminate through the intraperitoneal fluid.
Lucía Pascual-Antón, Beatriz Cardeñes, R. Sáinz de la Cuesta, L. González-Cortijo, M. López-Cabrera, C. Cabañas, Pilar Sandoval   +6 more
semanticscholar   +1 more source

Extraperitoneal parastomal metastasis of malignant peritoneal mesothelioma

BMJ Case Reports, 2021
A 75-year-old man was referred to surgical outpatient department with what was thought to be a parastomal hernia. Through further investigations with CT and biopsy, it was identified that the parastomal mass was metastatic peritoneal mesothelioma in the abdominal wall and subcutaneous tissue.
Jai Hoff, George Castrisos, Yiu Ming Ho, Monika Ruhnke   +3 more
openaire   +3 more sources

Adipocytes contribute to tumor progression and invasion of peritoneal metastasis by interacting with gastric cancer cells as cancer associated fibroblasts

Cancer Reports, 2022
Peritoneal metastasis (PM) is one of the most common causes of noncurative surgery and the most frequent recurrence pattern in gastric cancer (GC). During the process of PM, GC cells detached from primary tumor interact with human peritoneal mesothelial ...
Toshihide Hamabe-Horiike, S. Harada, Kyoko Yoshida, J. Kinoshita, Takahisa Yamaguchi, S. Fushida   +5 more
semanticscholar   +1 more source

Investigating the mechanisms of peritoneal metastasis in gastric adenocarcinoma using a novel ex vivo peritoneal explant model

Scientific Reports, 2022
Gastric adenocarcinoma, commonly known as stomach cancer, has a predilection for metastasis to the peritoneum, which portends limited survival. The peritoneal metastatic cascade remains poorly understood, and existing models fail to recapitulate key ...
Deanna Ng, Aiman Ali, Kiera Lee, Denise Eymael, Kento Abe, Shelly Luu, Karineh Kazazian, Yi Qing Lu, Savtaj Brar, James Conner, Marco Magalhaes, Carol J. Swallow   +11 more
doaj   +1 more source

CD31 and D2-40 Contribute to Peritoneal Metastasis of Colorectal Cancer by Promoting Epithelial-Mesenchymal Transition

Gut and Liver, 2021
Background/Aims: Colorectal cancer (CRC) patients often exhibit peritoneal metastasis, which negatively impacts their prognosis. CD31 and D2-40 have recently been suggested to be predictors of breast cancer prognosis, but their role in colorectal ...
Xinqiang Zhu, Gang Zhou, Peng Ni, Xuetong Jiang, Hailong Huang, Jianqiang Wu, Xiaohong Shi, Xiaoling Jiang, Jianing Liu   +8 more
doaj   +1 more source

Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer

Cellular and Molecular Life Sciences
Peritoneal metastasis, the third most common metastasis in colorectal cancer (CRC), has a poor prognosis for the rapid progression and limited therapeutic strategy.
Chaojun Zhu, Lan Teng, Yihong Lai, Xingxing Yao, Yuxin Fang, Zihuan Wang, Simin Lin, Haonan Zhang, Qingyuan Li, Ye Li, Jianqun Cai, Yue Zhang, Changjie Wu, Bing Huang, Aimin Li, Side Liu, Qiuhua Lai   +16 more
semanticscholar   +1 more source

Comprehensive Analysis of Peritoneal Metastasis Sequencing Data to Identify LINC00924 as a Prognostic Biomarker in Gastric Cancer

Cancer Management and Research, 2021
Background Gastric cancer peritoneal metastasis has high mortality. At present, there is no effective way to cure the patients diagnosed with gastric cancer peritoneal metastasis due to its indistinct molecular mechanism.
Yan Fang, Sihao Huang, Lei Han, Shuyi Wang, B. Xiong   +4 more
semanticscholar   +1 more source

Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers

Journal of Advanced Research
Introduction: Peritoneal metastasis is a prevalent form of gastric cancer spread, often resulting in poor outcomes. Due to the lack of clinical recommendation for surgery, current omics studies are limited to analyzing suspending malignant cells in ...
Song Li, Weiwei Zhang, Qian Yang, Shuhan Li, Xuanyu Zhou, Huan Wang, Ying Sun, Xiangyong Liu, Chunwang Ji, Jianyuan Zhou, Shulun Nie, Xuehui Wu, Jianqiao Jiao, Liliang Dou, Qinqin Hu, Fan Jiang, Qian Xu, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Wen Zhao, Shuang Wang, Jiahui Chu, Lian Liu   +24 more
doaj   +1 more source

Indocyanine green fluorescence-navigated laparoscopic metastasectomy for peritoneal metastasis of hepatocellular carcinoma: a case report

Surgical Case Reports, 2018
Background Indocyanine green (ICG) can selectively accumulate in primary hepatocellular carcinoma (HCC) and its extrahepatic metastases. ICG fluorescence imaging is an extremely sensitive intraoperative tool for detecting HCC foci and can be used to ...
Yoshihiro Miyazaki, Masanao Kurata, Yukio Oshiro, Osamu Shimomura, Kazuhiro Takahashi, Tatsuya Oda, Nobuhiro Ohkohchi   +6 more
doaj   +1 more source

TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer

Cell Death and Disease
Gastric cancer (GC), notorious for its poor prognosis, often advances to peritoneal dissemination, a crucial determinant of detrimental outcomes. This study intricately explores the role of the TGFβ-Smad-LIF axis within the tumor microenvironment in ...
Fangbin Zhang, Yan Yan, Xin-Gung Cao, Changqing Guo, Ke Wang, S. Lv   +5 more
semanticscholar   +1 more source