Results 81 to 90 of about 5,273,568 (326)

The ultrastructure of spinal cord perivascular spaces: Implications for the circulation of cerebrospinal fluid [PDF]

, 2017
Perivascular spaces play a pivotal role in the exchange between cerebrospinal and interstitial fluids, and in the clearance of waste in the CNS, yet their precise anatomical components are not well described. The aim of this study was to characterise the
Najafi, E, Lynne E. Bilston, Lam, MA, Hemley, SJ, Nicole G. F. Vella, Bilston, LE ; https://orcid.org/, Sarah J. Hemley, Marcus A. Stoodley, Vella, NGF, Elmira Najafi, Stoodley, MA, Magdalena A. Lam   +11 more
core   +2 more sources

Determinants of Perivascular Spaces in the General Population

Neurology, 2022
Background and Objectives Perivascular spaces (PVS) are emerging markers of cerebral small vessel disease (CSVD), but research on their determinants has been hampered by conflicting results from small single studies using heterogeneous rating methods. In
T. Evans, M. Knol, P. Schwingenschuh, K. Wittfeld, S. Hilal, M. Ikram, Florian Dubost, Kimberlin M H van Wijnen, P. Katschnig, Pinar Yilmaz, Marleen de Bruijne, M. Habes, Christopher Chen, Sönke Langer, H. Völzke, M. K. Ikram, H. Grabe, R. Schmidt, H. Adams, M. Vernooij   +19 more
semanticscholar   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Enlarged perivascular spaces in cerebral amyloid angiopathy [PDF]

, 2013
Enlarged perivascular spaces in cerebral amyloid ...
P Varlet (13445289), S Brandner (13445295), A Charidimou (13445172), DJ Werring (10872519), Z Jaunmuktane (13445283), Anna Peeters (13058832), HR Jaeger (14478903), JC Baron (14478939)   +7 more
core  

MRI-visible white matter perivascular spaces are related to cortical superficial siderosis in cerebral amyloid angiopathy [PDF]

, 2022
MRI-visible white matter perivascular spaces are related to cortical superficial siderosis in cerebral amyloid ...
Y Vandermneeren (13553827), A Charidimou (13445172), Anna Peeters (13058832), H R Jaeger (13553824), P Laloux (13444674), J-C Baron (13553830), Z Fox (13445256), D J Werringg (13553833)   +7 more
core  

Clinical associations and prognostic value of MRI-visible perivascular spaces in patients with ischemic stroke or TIA: a pooled analysis [PDF]

, 2023
Background and Objectives: Visible perivascular spaces are an MRI marker of cerebral small vessel disease and might predict future stroke. However, results from existing studies vary.
Bae, Hee-Joon, Teo, Kay Cheong, Jung, S, Karayiannis, Christopher, Chappell, Francesca M, Jäger, HR, Abrigo, J, Phan, Thanh, Leung, Thomas, Hara, Hideo, Nishihara, Masashi, Kim, YD, Srikanth, Velandai K, Fluri, F, Ambler, Gareth, Best, JG, Phan, TG, Al-Shahi Salman, R, Song , Tae-Jin, Srikanth, Velandai, Srikanth, Velandai K., Kuchcinski, G, Chu, Winnie, Köhler, Sebastian, Panos, Leonidas, Panos, L, Yakushiji, Yusuke, Werring, David J., Goeldlin, Martina B, Werring, DJ, Soo, Yannie O Y, Phan, Thanh G., Necioglu Orken, Dilek, Fluri, Felix, Makin, Stephen D J, Goeldlin, MB, Kuchcinski, Gregory, Leung, Thomas W, Lau, GKK, Lau, Gary Kui Kai, Mak, H, Chappell, F, Slater, Lee-Anne, Song, Tae Jin, Staals, Julie, Kubacka, Marta, Goeldlin, Martina B., Zietz, Annaelle, Zietz, A, Phan, Thanh G, Yakushiji, Y, Jung, Simon, Song, Tae-Jin, Abrigo, Jill, Bordet, R, Peters, Nils, Lau, Kui Kai, Kubacka, M, Best, Jonathan G., Lim, Jae Sung, Chappell, Francesca, Wardlaw, JM, Cheng, C, Kooi, ME, Dubost, F, Kvan Dam-Nolen, Dianne H, Lim, Jae-Sung, Heo, Ji-Hoe, Karayiannis, Christopher Charles, Slater, LA, Van Dam-Nolen, DHK, Lee, Keon-joo, Soo, Yannie O.Y., Slater, Lee Anne, Staals, J, Peters, N, Werring , David J, Makin, Stephen D.J., Chu, W, Cheng, Cyrus, Bellut, M, Mak, Henry, Necioglu Orken, D, Werring, David J, Leung, Thomas W., Köhler, S, Van Dam-Nolen, Dianne H.K., Jäger, Hans Rolf, Karayiannis, CC, Makin, Stephen, Demirelli, Derya Selçuk, Lim, JS, Yoshikawa, M, Wardlaw, Joanna M., Panos, Leonidas D, Selcuk Demirelli, Derya, Ambler, G, Srikanth, VK, Soo, YOY, Makin, SDJ, Yoshikawa, Masaaki, Nishihara, M, Al-Shahi Salman, Rustam; id_orcid, Best, Jonathan G, Kooi, M. Eline, Heo, Ji Hoe, Kim, Young Dae, Dae Kim, Young, Song, TJ, Bae, HJ, Lip, Gregory Y H, Teo, KC, van Dam-Nolen, Dianne H K, Du, Houwei, Kooi, M Eline, Bordet, Régis, Van Dam-Nolen, Dianne H.K.; id_orcid, Lee, KJ, Dubost, Florian, Wilson, Duncan, Lip, GYH, Heo, JH, Bellut, Maximilian, Wardlaw, Joanna M, Goeldlin, Martina Béatrice, Cheong Teo, Kay, Wilson, D, Lip, Gregory Y.H., Mak, Henry Ka Fung, Kooi, M Eline; id_orcid, Hara, H, Du, H, Leung, TW, Lee, Keon Joo, Selcuk Demirelli, D, Bae, Hee Joon, Al-Shahi Salman, Rustam   +136 more
core   +1 more source

The Association between Glymphatic System and Perivascular Macrophages in Brain Waste Clearance

Diagnostics
The glymphatic system suggests the convective bulk flow of cerebrospinal fluid (CSF) through perivascular spaces and the interstitial spaces of the brain parenchyma for the rapid removal of toxic waste solutes from the brain.
Jasleen Kaur, Edward D. Boyd, Guangliang Ding, Li Zhang, Hao Luo, Qingjiang Li, Lian Li, Min Wei, Julie Landschoot-Ward, Michael Chopp, Zhenggang Zhang, Quan Jiang   +11 more
doaj   +1 more source

Brain perivascular spaces and autism: clinical and pathogenic implications from an innovative volumetric MRI study

Frontiers in Neuroscience, 2023
IntroductionOur single-center case–control study aimed to evaluate the unclear glymphatic system alteration in autism spectrum disorder (ASD) through an innovative neuroimaging tool which allows to segment and quantify perivascular spaces in the white ...
Maria Alessandra Sotgiu, Alessandro Lo Jacono, Giuseppe Barisano, Laura Saderi, Vanna Cavassa, Andrea Montella, Paola Crivelli, Alessandra Carta, Stefano Sotgiu   +8 more
doaj   +1 more source

ON THE PERIVASCULAR SPACES IN THE NERVOUS CENTERS [PDF]

American Journal of Psychiatry, 1874
n ...
openaire   +1 more source