Results 191 to 200 of about 45,110 (263)

Integrated Stress Response (ISR) Modulators in Vascular Diseases. [PDF]

Cells
Kalinin A, Zubkova E, Beloglazova I, Parfyonova Y, Menshikov M.   +4 more
europepmc   +1 more source

Podocyte‐Derived Extracellular Vesicles Induce Endothelial Dysfunction by Triggering ER Stress in Glomerular Disease

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Podocyte injury and endothelial cell dysfunction are the hallmarks of glomerular disease. How these two events are connected remains largely unknown. This study aimed to delineate the role of extracellular vesicles (EVs) in mediating podocyte‐endothelial communication in glomerular disease.
Zhao Liu, Xi Liu, Xin Wen, Siyu Yan, Meizhi He, Jie Xu, Zhanji Zhan, Haili Zhu, Huishi Tan, Nan Jia, Youhua Liu   +10 more
wiley   +1 more source

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source

KLF10-IN-1 Attenuates RPE Cell Apoptosis and Experimental Diabetic Retinopathy Via the KLF10/PERK/eIF2α/ATF4/CHOP Pathway. [PDF]

Invest Ophthalmol Vis Sci
Hu W, Yang H, Zhu Q, Zheng G, Tan J, Lin Y, Wang Y, Tu Y, Zhou Q.   +8 more
europepmc   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia, Min Jiang, Yefei Huang, Kun Ding, Yansu Chen   +4 more
wiley   +1 more source

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review). [PDF]

Mol Med Rep
Zhang P, Cui Y, Liu C, Cui C, Zhang S, Zhang Y, Li F.   +6 more
europepmc   +1 more source

Dual Inhibitors of KRASG12D and HSP90 Are Effective against KRASG12D Inhibitor Resistance. [PDF]

Mol Cancer Ther
Pulido I, Gunder LC, Ying C, Wang Y, Dai Y, Yang Z, Rahnama A, Li J, Sun Y, Liu C, Zhou H, Wang G, Foley KP, Abdelhady K, Massad MG, Prince TL, Papautsky I, Ying W, Shimamura T.   +18 more
europepmc   +1 more source

The endoplasmic reticulum in mitochondrial protein targeting: A neuronal perspective on organelle crosstalk. [PDF]

Protein Sci
Hees JT, Harbauer AB.
europepmc   +1 more source

Hijacking the unfolded protein response (UPR) pathway: Balancing viral infection and host cell survival. [PDF]

J Biol Chem
Chen H, Liu D, Hua J, Wu M, Hua Y, Feng C, He Z, Moffett P, Zhang K.   +8 more
europepmc   +1 more source