Results 181 to 190 of about 46,487 (267)

Redox-modulated ERK dynamics support wound-dependent tissue formation during early planarian regeneration. [PDF]

iScience
Heleven M, Molina MD, Jaenen V, Bijnens K, Cebrià F, Smeets K.   +5 more
europepmc   +1 more source

Parenthood and CEO Responses to Media Criticism on Pay

Journal of Management Studies, EarlyView.
Abstract Research on media coverage of controversial corporate practices typically suggests firms respond instrumentally to mitigate stakeholder reactions. However, we argue that CEOs' moral concerns can sometimes override strategic considerations, because media criticism may expose them to scrutiny from personally valued audiences – for instance ...
Steffen Brenner, Georg Wernicke
wiley   +1 more source

GSK-J4 Suppresses Tumorigenesis by Targeting the PERK-c-Myc Pathway Through Endoplasmic Reticulum Stress Activation in Tuberous Sclerosis Complex. [PDF]

Int J Mol Sci
Lei X, Lang T, Li P, Wu C.
europepmc   +1 more source

Unpacking Agility in a Collaborative Product Innovation Process

Journal of Product Innovation Management, EarlyView.
ABSTRACT This research examines how agility manifests in collaborative innovation processes and how various agile activities influence the successful commercialization of innovation. The agile innovation process comprises joint strategic planning, joint problem solving, joint improvisation with collaborative partners, and community sensing to gain ...
Sabrina C. Thornton, Martin Johanson, David Sörhammar, Desirée Blankenburg Holm   +3 more
wiley   +1 more source

Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress. [PDF]

Biomedicines
Li F, Huang Y, Liu Z, Geng Y, Hu R, Song Y, Xu L, Zhang M.   +7 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

miR-489 induces immunogenic cell death in breast cancer by targeting LAPTM4B. [PDF]

Front Oncol
Gupta G, Titus R, Shaw S, Adusumilli N, Patel Y, Chen H.   +5 more
europepmc   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

ASCC3 promotes chemosensitivity in colorectal cancer cells. [PDF]

Sci Rep
Tu A, Martyn RDC, Cui S, Batenburg NL, Fayyazi R, Di Pastena F, Berthiaume L, Singh K, Saleem R, Scott GR, Berg T, Audet-Walsh É, Steinberg GR, Zhu XD.   +13 more
europepmc   +1 more source

Powers That Be: An Adventure in Metaphysics

Philosophical Investigations, EarlyView.
ABSTRACT This paper is an investigation into the increasingly popular trend amongst philosophers on the metaphysics of powers, exemplified by the statement: ‘To be real is to possess a power to affect (or to be affected by) other things’. First, I briefly trace the history of this idea (from the Eleatic dialectic of ancient times to present day quantum
David Rozema
wiley   +1 more source