Results 191 to 200 of about 46,487 (267)

Lipid overload triggers PERK-ALCAT1-mediated mitophagy failure in hepatocytes. [PDF]

iScience
Zhao W, Bao Y, Liu L, Gu Y, Liu X, Monroig Ó, Zhu T, Sun P, Tocher DR, Zhou Q, Jin M.   +10 more
europepmc   +1 more source

Bureaucratic Politics and Aid Allocation: Evidence From the US Agency for International Development

Regulation &Governance, EarlyView.
ABSTRACT We examine the impact of bureaucratic politics within the US Agency for International Development on the allocation of its development assistance. Existing studies of aid allocation have focused on donor interests, recipient needs, and recipient merit without accounting for the bureaucratic decision‐making process that helps determine these ...
Gus Greenstein, Mirko Heinzel
wiley   +1 more source

MAPK Phosphatase-3 Mediates Chronic Endoplasmic Reticulum Stress Promoting Hepatic Gluconeogenesis. [PDF]

Int J Mol Sci
Cao S, Du Y, Fang Z, Che L, Lin Y, Xu S, Jiang X, Liu G, Zhuo Y, Hua L, Sun M, Wu, Feng B.   +12 more
europepmc   +1 more source

Political Naturalisation: Conscripting Transit Citizens in the United Arab Emirates

Studies in Ethnicity and Nationalism, EarlyView.
ABSTRACT Since its formation, the United Arab Emirates has sought to construct a cohesive sense of national identity among its citizens, centred on a system of material and legal privileges granted exclusively to Emirati nationals. A pillar of its nation‐building project was the strict exclusion of foreigners from citizenship and the upholding of a ...
Mira Al Hussein
wiley   +1 more source

Pan-cancer analysis reveals differential PERK expression across tumour types and its potential as a therapeutic target. [PDF]

Discov Oncol
Kumar S, Han N, Tsagkogeorga G, Wan MLY.
europepmc   +1 more source

A Role‐Mediated, Motivational Account of Interpersonal Trust

Theoria, EarlyView.
ABSTRACT Social interactions rarely occur with persons in the abstract. Rather, we engage with parents, teachers, neighbours—that is, persons in various capacities, as occupants of social roles. If social interactions are role‐mediated, then interpersonal trust must also be directed at persons in their roles.
SuddhaSatwa GuhaRoy
wiley   +1 more source

The PERK inhibitor GSK2606414 evokes developmental defects in zebrafish consistent with Wolcott-Rallison syndrome phenotypes. [PDF]

Pharmacol Rep
Almeida LM, Lima LP, Oliveira NAS, Silva RFO, Sousa B, Bessa J, Pinho BR, Oliveira JMA.   +7 more
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

α-Hederin Alleviates Endoplasmic Reticulum Stress by Upregulating TRIM38 Expression, Thereby Inhibiting Hepatic Stellate Cell Activation and Liver Fibrosis. [PDF]

Biomedicines
Xu W, Yang Y, Li F, Li C, Tang G, Zhang B, Cheng M.   +6 more
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source