Results 81 to 90 of about 1,259,046 (413)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Biocontrol mechanisms of Trichoderma harzianum against soybean charcoal rot caused by Macrophomina phaseolina

Journal of Plant Protection Research, 2016
Throughout the world, charcoal rot, caused by Macrophomina phaseolina, is one of the most destructive and widespread diseases of crop plants such as soybean. In this study, the biological control capability of 11 Trichoderma spp.
Khaledi Nima, Taheri Parissa
doaj   +1 more source

Ascorbate Peroxidase and Catalase Activities and Their Genetic Regulation in Plants Subjected to Drought and Salinity Stresses

International Journal of Molecular Sciences, 2015
Hydrogen peroxide (H2O2), an important relatively stable non-radical reactive oxygen species (ROS) is produced by normal aerobic metabolism in plants. At low concentrations, H2O2 acts as a signal molecule involved in the regulation of specific biological/
A. Sofo, A. Scopa, M. Nuzzaci, A. Vitti
semanticscholar   +1 more source

Phytochemical Screening and in vivo antioxidant activity of Ethanolic extract of caesalpinia bondus (L.) Roxb [PDF]

, 2012
Phytochemical screening, antioxidant activity in vivo and lipid peroxidation of 75 % ethanolic extract of young twigs and leaves of Caesalpinia bonduc were carried out by chemical test, and assessment of catalase and peroxidase activities and lipid ...
Akindahunsi , A. A, Ntube , C. A, Ogunlana , O. E, Ogunlana , O. O, Olagunju , J. A   +4 more
core   +1 more source

Graphene Quantum Dot-Based Electrochemical Immunosensors for Biomedical Applications [PDF]

, 2019
In the area of biomedicine, research for designing electrochemical sensors has evolved over the past decade, since it is crucial to selectively quantify biomarkers or pathogens in clinical samples for the efficacious diagnosis and/or treatment of various
Altintas, Zeynep, Mansuriya, Bhargav D.
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Characterization of peroxidase and catalase genes in defense mechanisms of Physcomitrella patens [PDF]

, 2019
Systemic acquired resistance (SAR) and the hypersensitive response (HR) are two important induced defense mechanisms in plants. SAR is the development of an enhanced resistance to a pathogen due to a prior encounter.
Ciulla, Lauren
core   +1 more source

Effects of mutations in the helix G region of horseradish peroxidase [PDF]

, 2008
Horseradish peroxidase (HRP) has long attracted intense research interest and is used in many biotechnological fields, including diagnostics, biosensors and biocatalysis.
Barry J. Ryan, Batra, Chakrabarti, Chang, Chattopadhyay, Ciarán Ó'Fágáin, Coates, Dai, Dunford, French, Gajhede, Garcia, Gonera, Gorman, Grigorenko, Guex, Hakamada, Haque, Hassani, Howes, Ignatenko, Jager, Kaposi, Khmelnitsky, Krowarsch, Kwon, Lei, Lin, Lipovsek, Liu, Liu, Machado, Miland, Miland, Mogharrab, Moosavi-Movahedi, Morawski, Nagano, Numata, O'Brien, O'Brien, Orlova, Ozaki, Pina, Priori, Ryan, Ryan, Ryan, Ryu, Sambrook, Santucci, Savenkova, Smeller, Smith, Tams, Tanaka, Tanaka, Ugarova, Urrutigoity, Wang   +59 more
core   +1 more source

Immunohistochemical pitfalls in the demonstration of insulin-degrading enzyme in normal and neoplastic human tissues [PDF]

arXiv, 2007
Previously, we have identified the cytoplasmic zinc metalloprotease insulin-degrading enzyme(IDE) in human tissues by an immunohistochemical method involving no antigen retrieval (AR) by pressure cooking to avoid artifacts by endogenous biotin exposure and a detection kit based on the labeled streptavidin biotin (LSAB) method. Thereby, we also employed
arxiv  

Dynamics of protein-protein encounter: a Langevin equation approach with reaction patches [PDF]

, 2008
We study the formation of protein-protein encounter complexes with a Langevin equation approach that considers direct, steric and thermal forces. As three model systems with distinctly different properties we consider the pairs barnase:barstar, cytochrome c:cytochrome c peroxidase and p53:MDM2.
arxiv   +1 more source