Results 81 to 90 of about 11,517 (308)

Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions. [PDF]

Proceedings of the National Academy of Sciences, 1995
The Bacillus subtilis mrgA gene encodes an abundant DNA-binding protein that protects cells against the lethal effects of H2O2. Transcription of mrgA is induced by H2O2 or by entry into stationary phase when manganese and iron levels are low. We have selected for strains derepressed for transcription of mrgA in the presence of Mn(II). The resulting cis-
L, Chen, L, Keramati, J D, Helmann
openaire   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Saliva Levels of 15-F-Isoprostane as Biomarker of Lipid Peroxidation in Autistic Children

European Journal of Inflammation, 2007
Autism is a complex neurodevelopmental disorder that usually presents itself in early childhood and is thought to be influenced by genetic and environmental factors.
A. Karamouzi, D. Kovachev, I. Karamouzis, M. Antoniadou-Hitoglou, I. Tsikoulas, N. Aggelopoulou-Sakadami   +5 more
doaj   +1 more source

Functional traits of expanding, thicket-forming shrubs: contrasting strategies between exotic and native species [PDF]

, 2017
Woody expansion has been documented for decades in many different systems globally, often yielding vast changes in ecosystem functioning. While causes and consequences of woody expansion have been well documented, few studies have addressed plant ...
Shiflett, Sheri A., Young, Donald R., Zinnert, Julie C.   +2 more
core   +2 more sources

Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation [PDF]

Biochemical and Biophysical Research Communications, 2012
In cells exposed to environmental stress, inhibition of translation initiation conserves energy for the repair of cellular damage. Untranslated mRNAs that accumulate in these cells move to discrete cytoplasmic foci known as stress granules (SGs). The assembly of SGs helps cells to survive under adverse environmental conditions.
Mohamed M, Emara, Ken, Fujimura, Daniele, Sciaranghella, Victoria, Ivanova, Pavel, Ivanov, Paul, Anderson   +5 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay. [PDF]

PLoS ONE, 2015
BACKGROUND:Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether levosimendan could modulate the cross-talk
Elena Grossini, Kevin Bellofatto, Serena Farruggio, Lorenzo Sigaudo, Patrizia Marotta, Giulia Raina, Veronica De Giuli, David Mary, Piero Pollesello, Rosalba Minisini, Mario Pirisi, Giovanni Vacca   +11 more
doaj   +1 more source

Anoxic stress leads to hydrogen peroxide formation in plant cells [PDF]

Journal of Experimental Botany, 2001
Hydrogen peroxide (H2O2) was detected cytochemically in plant tissues during anoxia and re-oxygenation by transmission electron microscopy using its reaction with cerium chloride to produce electron dense precipitates of cerium perhydroxides. Anoxia-tolerant yellow flag iris (Iris pseudacorus) and rice (Oryza sativa), and anoxia-intolerant wheat ...
O B, Blokhina, T V, Chirkova, K V, Fagerstedt   +2 more
openaire   +2 more sources

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source