Results 51 to 60 of about 19,535 (281)
Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?
Asian Journal of Andrology, 2015 This chapter explores the possibility that capacitation and apoptosis are linked processes joined by their common dependence on the continued generation of reactive oxygen species (ROS).
Robert J Aitken +2 more
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Peroxiredoxins and their expression in ependymomas
Journal of Clinical Pathology, 2012 AimsPeroxiredoxins I–VI (Prxs) have recently been shown to have a role in the tumorigenesis of astrocytic brain tumours. In some tumour types they are associated with Nrf2 (transcription factor NF-E2-related factor), a sensor of oxidative stress, and DJ-1 (also known as PARK7), a protein known to stabilise Nrf2.MethodsWe investigated the ...
Mikkonen Eloise +8 more
openaire +3 more sources
International Journal of Cell Biology, 2014 Calorie restriction (CR) is an intervention extending the life spans of many organisms. The mechanisms underlying CR-dependent retardation of aging are still poorly understood.
Mikael Molin, Ayse Banu Demir
doaj +1 more source
Molecules and Cells, 2016 Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that reduce peroxides, with a conserved cysteine residue, designated the "peroxidatic" Cys (CP) serving as the site of oxidation by peroxides (Hall et al., 2011; Rhee et al., 2012).
openaire +3 more sources
Antioxidants, 2019 Peroxiredoxins (PRDXs) are antioxidant enzymes that protect cells from oxidative stress and play a role in reactive oxygen species (ROS)-mediated signaling.
Cristian O’Flaherty +3 more
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Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage
Asian Journal of Andrology, 2015 Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan +7 more
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Frontiers in Marine Science, 2021 Berberine hydrochloride is an isoquinoline alkaloid, which has antitumoral, antibacterial, and antiviral activities in vivo and in vitro. Charybdis japonica is one of the main economic species of crab in Southeast Asia. We studied the molecular mechanism
Mingming Han +8 more
doaj +1 more source
A primer on peroxiredoxin biochemistry [PDF]
Free Radical Biology and Medicine, 2015 Peroxiredoxins were not recognized as a family of enzymes until the 1990s but are now known to be the dominant peroxidases in most organisms. Here, the history and fundamental properties of peroxiredoxins are briefly reviewed, with a special focus on describing how an exquisitely tunable balance between fully folded and locally unfolded conformations ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Biologia Plantarum, 2014 The current work compared the physiological characteristics of plantain (Musa AAB) plantlets micropropagated in temporary immersion bioreactors (TIB) and on a gelled medium (GM).
C. E. Aragón +5 more
doaj +1 more source