Results 231 to 240 of about 248,501 (390)

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, EarlyView.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

Proceedings of the National Academy of Sciences of the United States of America, 1993
H. Keller, C. Dreyer, J. Medin, A. Mahfoudi, K. Ozato, W. Wahli   +5 more
semanticscholar   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Retinoid X receptor γ interacts with peroxisome proliferator-activated receptor-γ to promote browning during adipose tissue differentiation. [PDF]

Adipocyte
Chen D, Woraikat S, Guo X, Yang F, Tang C, He F, Qian K.   +6 more
europepmc   +1 more source

Reversing Vascular Dysfunction in Rheumatoid Arthritis: Improved Augmentation Index but Not Endothelial Function With Peroxisome Proliferator–Activated Receptor γ Agonist Therapy

, 2014
Michelle J. Ormseth, Annette Oeser, Andrew Cunningham, Aihua Bian, Ayumi Shintani, Joseph F. Solus, S. Bobo Tanner, C. Michael Stein   +7 more
openalex   +1 more source

AB0098 Peroxisome proliferator-activated receptor-gamma coactivator-1Β facilitates migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis via activation of canonical and non-canonical nf-Κb signalling pathway [PDF]

, 2018
J.-D. Ma, Tao Yan, Yonggao Mou, Jun Jing, Y.-Q. Mo, Lie Dai   +5 more
openalex   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate. [PDF]

Toxicol Sci
Khan Y, Schmidt AM, Oldro KJ, Zhu X, Kramer AR, Hamilton SR, Bleil KO, Krisko RM, Zitzow JD, Tian Y, Chang SC, Walter V, Cohen SM, Gonzalez FJ, Patterson AD, Peters JM.   +15 more
europepmc   +1 more source

Ninjin’yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression

, 2020
Atsushi Miyamoto, Kazuhisa Asai, Hideaki Kadotani, Naomi Maruyama, Hiroko Kubo, Atsuko Okamoto, Kōichi Sato, Kenneth M. Yamada, Naoki Ijiri, Tetsuya Watanabe, Takahisa Kawaguchi   +10 more
openalex   +1 more source

Analysis of the peroxisome proliferator activated receptor-α (PPARα/Ppara)-regulated transcriptome in mouse skeletal muscle

, 2015
BN Finck
openalex   +1 more source