Results 221 to 230 of about 95,453 (303)

Scaffold implantation <i>vs.</i> intravenous delivery: a comparative preclinical animal study evaluating peroxisome proliferator-activated receptor gamma coactivator 1-alpha adipose-derived stem cells in liver fibrosis treatment. [PDF]

Ann Surg Treat Res
Ahn J, Park JH, Choi HJ, Lee D, Hong HE, Kim OH, Kim SJ.   +6 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Adipocyte‑rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator‑activated receptor gamma/ABCG2 in epithelial ovarian cancer. [PDF]

Int J Mol Med
Chen S, Liu Z, Wu H, Wang B, Ouyang Y, Liu J, Zheng X, Zhang H, Li X, Feng X, Li Y, Shen Y, Zhang H, Xiao B, Yu C, Deng W.   +15 more
europepmc   +1 more source

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

, 2017
et al,, Yee, Derek
core   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Effects of Systemic Peroxisome Proliferator-Activated Receptor Gamma Inhibition on Bone and Immune Cells in Aged Female Mice. [PDF]

J Gerontol A Biol Sci Med Sci
Shi X, Ding K, Rosario R, Ajith A, Su Y, Shaw S, McGee-Lawrence M, Lu XY, Horuzsko A, Isales CM.   +9 more
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Peroxisome proliferator-activated receptor gamma (PPAR-γ) activation through gut microbiota modulation as a novel therapeutic approach against anastomotic leak after colorectal cancer surgery. [PDF]

J Gastrointest Oncol
Núñez-Sánchez MÁ, Martínez-Sánchez MA, Ramos-Molina B.   +2 more
europepmc   +1 more source

Ihmisen apolipoproteiinien ekspressio ja niiden säätely PPAR:llä [PDF]

Uski, Oskari
core  

The efficacy and physiological bases of small muscle mass exercise in health and disease

Experimental Physiology, EarlyView.
Abstract The conventional approach to aerobic exercise prescription involves large muscle mass exercise and the manipulation of variables such as training intensity, duration and frequency to promote desired adaptations. However, during whole‐body exercise, central limitations (i.e., neural, pulmonary and/or cardiac) constrain exercise tolerance and ...
Callum G. Brownstein
wiley   +1 more source