Results 11 to 20 of about 43,085 (313)

Brain peroxisomes [PDF]

Biochimie, 2014
Peroxisomes are essential organelles in higher eukaryotes as they play a major role in numerous metabolic pathways and redox homeostasis. Some peroxisomal abnormalities, which are often not compatible with life or normal development, were identified in severe demyelinating and neurodegenerative brain diseases.
Trompier, Doriane, Vejux, A., Zarrouk, A., Gondcaille, Catherine, Geillon, Flore, Nury, T., Savary, Stéphane, Lizard, Gérard   +7 more
openaire   +4 more sources

Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging

Antioxidants, 2022
Peroxisomes are key regulators of cellular and metabolic homeostasis. These organelles play important roles in redox metabolism, the oxidation of very-long-chain fatty acids (VLCFAs), and the biosynthesis of ether phospholipids.
Jinoh Kim, Hua Bai
doaj   +1 more source

Expanding functional repertoires of fungal peroxisomes: contribution to growth and survival processes

Frontiers in Physiology, 2013
It has long been regarded that the primary function of fungal peroxisomes is limited to the β-oxidation of fatty acids, as mutants lacking peroxisomal function fail to grow in minimal medium containing fatty acids as the sole carbon source.
Jun-ichi eMARUYAMA, Katsuhiko eKITAMOTO
doaj   +1 more source

The subset of peroxisomal tail-anchored proteins do not reach peroxisomes via ER, instead mitochondria can be involved.

PLoS ONE, 2023
Peroxisomes are membrane-enclosed organelles with important roles in fatty acid breakdown, bile acid synthesis and biosynthesis of sterols and ether lipids. Defects in peroxisomes result in severe genetic diseases, such as Zellweger syndrome and neonatal
Tamara Somborac, Güleycan Lutfullahoglu Bal, Kaneez Fatima, Helena Vihinen, Anja Paatero, Eija Jokitalo, Ville O Paavilainen, Svetlana Konovalova   +7 more
doaj   +1 more source

Phytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes.

Journal of Lipid Research, 1995
To understand the possible role of phytanoyl-CoA ligase, present in the membrane, in the oxidation of phytanic acid in the matrix of peroxisomes (Pahan, K. and I. Singh. 1993. FEBS Lett.
K Pahan, I Singh
doaj   +1 more source

Metabolic interplay between peroxisomes and other subcellular organelles including mitochondria and the endoplasmic reticulum

Frontiers in Cell and Developmental Biology, 2016
Peroxisomes are unique subcellular organelles which play an indispensable role in several key metabolic pathways which include: (1.) etherphospholipid biosynthesis; (2.) fatty acid beta-oxidation; (3.) bile acid synthesis; (4.) docosahexaenoic acid (DHA)
Ronald J.A. Wanders, Hans R. Waterham, Sacha eFerdinandusse   +2 more
doaj   +1 more source

Msp1 and Pex19-Pex3 cooperate to achieve correct localization of Pex15 to peroxisomes. [PDF]

FEBS J
Matsumoto S, Kogure Y, Ono S, Numata T, Endo T.   +4 more
europepmc   +3 more sources

The impact of peroxisomes on cellular ageing and death

Frontiers in Oncology, 2012
Peroxisomes are ubiquitous eukaryotic organelles, which perform a plethora of functions including hydrogen peroxide metabolism and β-oxidation of fatty acids.
Selvambigai eManivannan, Christian Quintus Scheckhuber, Marten eVeenhuis, Ida Joanna van der Klei   +3 more
doaj   +1 more source

Reduced peroxisomal import triggers peroxisomal retrograde signaling [PDF]

Cell Reports, 2021
Maintaining organelle function in the face of stress is known to involve organelle-specific retrograde signaling. Using Caenorhabditis elegans, we present evidence of the existence of such retrograde signaling for peroxisomes, which we define as the peroxisomal retrograde signaling (PRS).
Rackles, Elisabeth, Witting, Michael, Forné, Ignasi, Zhang, Xing, Zacherl, Judith, Schrott, Simon, Fischer, Christian, Ewbank, Jonathan, Osman, Christof, Imhof, Axel, Rolland, Stéphane   +10 more
openaire   +5 more sources

Rosy Beginnings: Studying Peroxisomes in Drosophila

Frontiers in Cell and Developmental Biology, 2020
Research using the fruit fly Drosophila melanogaster has traditionally focused on understanding how mutations affecting gene regulation or function affect processes linked to animal development.
C. Pridie, Kazuki Ueda, Andrew J. Simmonds   +2 more
doaj   +1 more source