Results 11 to 20 of about 42,473 (314)
Biochimie, 2014 Peroxisomes are essential organelles in higher eukaryotes as they play a major role in numerous metabolic pathways and redox homeostasis. Some peroxisomal abnormalities, which are often not compatible with life or normal development, were identified in severe demyelinating and neurodegenerative brain diseases.
Trompier, Doriane +7 more
openaire +4 more sources
Journal of Histochemistry & Cytochemistry, 1973 Estelle J. McGroarty, N. E. Tolbert
openalex +4 more sources
The return of the peroxisome [PDF]
Journal of Cell Science, 2006 Of the classical compartments of eukaryotic cells, peroxisomes were the last to be discovered. They are small, single-membrane-bound vesicles involved in cellular metabolism, most notably the β-oxidation of fatty acids. Characterization of their properties and behavior has progressed rather slowly.
van der Zand, A. +3 more
openaire +5 more sources
Frontiers in Physiology, 2013 It has long been regarded that the primary function of fungal peroxisomes is limited to the β-oxidation of fatty acids, as mutants lacking peroxisomal function fail to grow in minimal medium containing fatty acids as the sole carbon source.
Jun-ichi eMARUYAMA, Katsuhiko eKITAMOTO
doaj +1 more source
Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging
Antioxidants, 2022 Peroxisomes are key regulators of cellular and metabolic homeostasis. These organelles play important roles in redox metabolism, the oxidation of very-long-chain fatty acids (VLCFAs), and the biosynthesis of ether phospholipids.
Jinoh Kim, Hua Bai
doaj +1 more source
PLoS ONE, 2023 Peroxisomes are membrane-enclosed organelles with important roles in fatty acid breakdown, bile acid synthesis and biosynthesis of sterols and ether lipids. Defects in peroxisomes result in severe genetic diseases, such as Zellweger syndrome and neonatal
Tamara Somborac +7 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2016 Peroxisomes are unique subcellular organelles which play an indispensable role in several key metabolic pathways which include: (1.) etherphospholipid biosynthesis; (2.) fatty acid beta-oxidation; (3.) bile acid synthesis; (4.) docosahexaenoic acid (DHA)
Ronald J.A. Wanders +2 more
doaj +1 more source
Journal of Lipid Research, 1995 To understand the possible role of phytanoyl-CoA ligase, present in the membrane, in the oxidation of phytanic acid in the matrix of peroxisomes (Pahan, K. and I. Singh. 1993. FEBS Lett.
K Pahan, I Singh
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006 Peroxisomes are indispensable for proper functioning of human cells. They efficiently compartmentalize enzymes responsible for a number of metabolic processes, including the absolutely essential beta-oxidation of specific fatty acid chains. These and other oxidative reactions produce hydrogen peroxide, which is, in most instances, immediately processed
Paul A. Walton +2 more
openaire +2 more sources
The impact of peroxisomes on cellular ageing and death
Frontiers in Oncology, 2012 Peroxisomes are ubiquitous eukaryotic organelles, which perform a plethora of functions including hydrogen peroxide metabolism and β-oxidation of fatty acids.
Selvambigai eManivannan +3 more
doaj +1 more source