Results 31 to 40 of about 53,252 (304)
Journal of Lipid Research, 1989 The effect of gemfibrozil on the fine structure of peroxisomes across the rat liver lobule was investigated by light and electron microscopy using the alkaline diaminobenzidine (DAB) medium for the visualization of catalase peroxidatic activity. The oral
K Gorgas, S K Krisans
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The autophagic degradation of cytosolic pools of peroxisomal proteins by a new selective pathway. [PDF]
, 2019 Damaged or redundant peroxisomes and their luminal cargoes are removed by pexophagy, a selective autophagy pathway. In yeasts, pexophagy depends mostly on the pexophagy receptors, such as Atg30 for Pichia pastoris and Atg36 for Saccharomyces cerevisiae ...
Farré, Jean-Claude +8 more
core +2 more sources
A critical reflection on the principles of peroxisome formation in yeast
Frontiers in Physiology, 2014 We have evaluated the current knowledge on peroxisome proliferation in yeast. In wild-type cells, peroxisomes multiply predominantly by fission at conditions that require peroxisome function(s) for growth.
Ida J Van Der Klei, Marten eVeenhuis
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C. elegans fatty acid two-hydroxylase regulates intestinal homeostasis by affecting heptadecenoic acid production [PDF]
, 2018 Background/Aims: The hydroxylation of fatty acids at the C-2 position is the first step of fatty acid α-oxidation and generates sphingolipids containing 2-hydroxy fatty acyl moieties.
Fu, Rong +10 more
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Annals of Medicine, 1992 The peroxisomal diseases, which are rare inborn metabolic errors, often have serious effects on the well being of the individual and many of them are fatal at an early age. The Zellweger cerebro-hepato-renal syndrome represents a group consisting of diseases with a generalized loss of peroxisomal functions and is considered as a prototype for ...
P M, Palosaari +2 more
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Peroxisome Metabolism in Cancer
Cells, 2020 Peroxisomes are metabolic organelles involved in lipid metabolism and cellular redoxbalance. Peroxisomal function is central to fatty acid oxidation, ether phospholipid synthesis, bile acidsynthesis, and reactive oxygen species homeostasis.
Jung-Ae Kim
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Peroxisomes are required for lipid metabolism and muscle function in Drosophila melanogaster. [PDF]
PLoS ONE, 2014 Peroxisomes are ubiquitous organelles that perform lipid and reactive oxygen species metabolism. Defects in peroxisome biogenesis cause peroxisome biogenesis disorders (PBDs).
Joseph E Faust +8 more
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Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]
, 2017 Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim +17 more
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Journal of Lipid Research, 1985 Rat liver peroxisomes have been found to oxidize 26-hydroxycholesterol, the product of cholesterol C-26 hydroxylation to 3 beta-hydroxy-5-cholenoic acid.
S K Krisans +4 more
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The Human Thioesterase II Protein Binds to a Site on HIV-1 Nef Critical for CD4 Down-regulation [PDF]
, 2000 A HIV-1 Nef affinity column was used to purify a 35-kDa Nef-interacting protein from T-cell lysates. The 35-kDa protein was identified by peptide microsequence analysis as the human thioesterase II (hTE) enzyme, an enzyme previously identified in a yeast
Baltimore, David +4 more
core +1 more source