Results 51 to 60 of about 34,934 (252)
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006 Genomes provide us with a blue print for the potential of a cell. However, the activity of a cell is expressed in its proteome. Full understanding of the complexity of cells demands a comprehensive view of the proteome; its interactions, activity states and organization.
Saleem, R.A. +2 more
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Advanced Science, EarlyView.A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao +11 more
wiley +1 more source
, 2016 Significance: Peroxisomes are organelles present in most eukaryotic cells. The organs with the highest density of peroxisomes are the liver and kidneys. Peroxisomes possess more than fifty enzymes and fulfill a multitude of biological tasks.
Vasko, Radovan
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Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
, 1979 Cytochemical, biochemical and morphological changes in peroxisomes have been described in human metabolic disorders, in experimental models of disease and in response to drugs and toxins.
S Goldfischer
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Advanced Science, EarlyView.A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
[Peroxisomes and peroxisomal diseases].
Postepy higieny i medycyny doswiadczalnej, 1991 This paper is on peroxisomes ("microbodies") dealing with various aspects of their physiological significance including the central question of biogenesis of peroxisomes. Attention is also focused on how peroxisomes are involved in human pathology and the so-called peroxisomal diseases are described.
M, Petelenz +3 more
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Anaerobic peroxisomes in Archamoebae
, 2021 Peroxisomes and mitochondria play a key role in oxygen metabolism. It was widely accepted that the evolutionary adaptation of eukaryotes to anaerobiosis is reflected by the metabolic reduction of mitochondria, and concomitant loss of peroxisomes.
Le, Tien
core
Advanced Science, EarlyView.HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li +8 more
wiley +1 more source
Autophagic Machinery of Plant Peroxisomes
, 2019 Peroxisomes are cell organelles that play an important role in plants in many physiological and developmental processes. The plant peroxisomes harbor enzymes of the β-oxidation of fatty acids and the glyoxylate cycle; photorespiration ...
Sławomir Borek +4 more
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